| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 219699 |
Name | UNC5B |
Synonym | UNC5H2|p53RDL1;unc-5 homolog B (C. elegans);UNC5B;unc-5 homolog B (C. elegans) |
Definition | netrin receptor UNC5B|p53-regulated receptor for death and life protein 1|protein unc-5 homolog 2|protein unc-5 homolog B|transmembrane receptor Unc5H2|unc-5 homolog 2 |
Position | 10q22.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 17505 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Axon guidance mediated by netrin;PANTHER;P00009 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Netrin-1 signaling;PID Reactome;500088 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Role of DCC in regulating apoptosis;PID Reactome;500280 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
Disease | PSYCH;GAD |
Disease | attention-deficit hyperactivity disorder;GAD |
Disease | Cancer;FunDO |
Disease | ADHD;GAD |
Disease | Attention deficit hyperactivity disorder;NHGRI |
|
External Links |
|
Links to Entrez Gene | 219699 |
Links to all GeneRIF Items | 219699 |
Links to iHOP | 219699 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>219699 : length: 2838 atgggggcccggagcggagctcggggcgcgctgctgctggcactgctgctctgctgggac ccgaggctgagccaagcaggcactgattctggcagcgaggtgctccctgactccttcccg tcagcgccagcagagccgctgccctacttcctgcaggagccacaggacgcctacattgtg aagaacaagcctgtggagctccgctgccgcgccttccccgccacacagatctacttcaag tgcaacggcgagtgggtcagccagaacgaccacgtcacacaggaaggcctggatgaggcc accggcctgcgggtgcgcgaggtgcagatcgaggtgtcgcggcagcaggtggaggagctc tttgggctggaggattactggtgccagtgcgtggcctggagctccgcgggcaccaccaag agtcgccgagcctacgtccgcatcgcctacctgcgcaagaacttcgatcaggagcctctg ggcaaggaggtgcccctggaccatgaggttctcctgcagtgccgcccgccggagggggtg cctgtggccgaggtggaatggctcaagaatgaggatgtcatcgaccccacccaggacacc aacttcctgctcaccatcgaccacaacctcatcatccgccaggcccgcctgtcggacact gccaactatacctgcgtggccaagaacatcgtggccaaacgccggagcaccactgccacc gtcatcgtctacgtgaatggcggctggtccagctgggcagagtggtcaccctgctccaac cgctgtggccgaggctggcagaagcgcacccggacctgcaccaaccccgctccactcaac ggaggggccttctgcgagggccaggcattccagaagaccgcctgcaccaccatctgccca gtcgatggggcgtggacggagtggagcaagtggtcagcctgcagcactgagtgtgcccac tggcgtagccgcgagtgcatggcgcccccaccccagaacggaggccgtgactgcagcggg acgctgctcgactctaagaactgcacagatgggctgtgcatgcaaaataagaaaactcta agcgaccccaacagccacctgctggaggcctcaggggatgcggcgctgtatgcggggctc gtggtggccatcttcgtggtcgtggcaatcctcatggcggtgggggtggtggtgtaccgc cgcaactgccgtgacttcgacacagacatcactgactcatctgctgccctgactggtggt ttccaccccgtcaactttaagacggcaaggcccagcaacccgcagctcctacacccctct gtgcctcctgacctgacagccagcgccggcatctaccgcggacccgtgtatgccctgcag gactccaccgacaaaatccccatgaccaactctcctctgctggaccccttacccagcctt aaggtcaaggtctacagctccagcaccacgggctctgggccaggcctggcagatggggct gacctgctgggggtcttgccgcctggcacataccctagcgatttcgcccgggacacccac ttcctgcacctgcgcagcgccagcctcggttcccagcagctcttgggcctgccccgagac ccagggagcagcgtcagcggcacctttggctgcctgggtgggaggctcagcatccccggc acaggggtcagcttgctggtgcccaatggagccattccccagggcaagttctacgagatg tatctactcatcaacaaggcagaaagtaccctcccgctttcagaagggacccagacagta ttgagcccctcggtgacctgtggacccacaggcctcctgctgtgccgccccgtcatcctc accatgccccactgtgccgaagtcagtgcccgtgactggatctttcagctcaagacccag gcccaccagggccactgggaggaggtggtgaccctggatgaggagaccctgaacacaccc tgctactgccagctggagcccagggcctgtcacatcctgctggaccagctgggcacctac gtgttcacgggcgagtcctattcccgctcagcagtcaagcggctccagctggccgtcttc gcccccgccctctgcacctccctggagtacagcctccgggtctactgcctggaggacacg cctgtagcactgaaggaggtgctggagctggagcggactctgggcggatacttggtggag gagccgaaaccgctaatgttcaaggacagttaccacaacctgcgcctctccctccatgac ctcccccatgcccattggaggagcaagctgctggccaaataccaggagatccccttctat cacatttggagtggcagccagaaggccctccactgcactttcaccctggagaggcacagc ttggcctccacagagctcacctgcaagatctgcgtgcggcaagtggaaggggagggccag atattccagctgcataccactctggcagagacacctgctggctccctggacactctctgc tctgcccctggcagcactgtcaccacccagctgggaccttatgccttcaagatcccactg tccatccgccagaagatatgcaacagcctagatgcccccaactcacggggcaatgactgg cggatgttagcacagaagctctctatggaccggtacctgaattactttgccaccaaagcg agccccacgggtgtgatcctggacctctgggaagctctgcagcaggacgatggggacctc aacagcctggcgagtgccttggaggagatgggcaagagtgagatgctggtggctgtggcc accgacggggactgctga |
Protein Sequence |
>219699 : length: 945 MGARSGARGALLLALLLCWDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIV KNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQIEVSRQQVEEL FGLEDYWCQCVAWSSAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGV PVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTAT VIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICP VDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTL SDPNSHLLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRRNCRDFDTDITDSSAALTGG FHPVNFKTARPSNPQLLHPSVPPDLTASAGIYRGPVYALQDSTDKIPMTNSPLLDPLPSL KVKVYSSSTTGSGPGLADGADLLGVLPPGTYPSDFARDTHFLHLRSASLGSQQLLGLPRD PGSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTV LSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIFQLKTQAHQGHWEEVVTLDEETLNTP CYCQLEPRACHILLDQLGTYVFTGESYSRSAVKRLQLAVFAPALCTSLEYSLRVYCLEDT PVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFY HIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEGQIFQLHTTLAETPAGSLDTLC SAPGSTVTTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKA SPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATDGDC |