General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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---|---|
Gene ID | 23586 |
Name | DDX58 |
Synonym | RIG-I|RIGI|RLR-1|SGMRT2;DEAD (Asp-Glu-Ala-Asp) box polypeptide 58;DDX58;DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
Definition | DEAD box protein 58|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide|RNA helicase RIG-I|probable ATP-dependent RNA helicase DDX58|retinoic acid-inducible gene 1 protein|retinoic acid-inducible gene I protein |
Position | 9p12 |
Gene Type | protein-coding |
TSG scores |
Description |
TUSON ranking | 5828 |
TUSON P-value | 1 |
Pathways and Diseases |
|
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | Cytosolic DNA-sensing pathway;KEGG PATHWAY;hsa04623 |
External Links |
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Links to Entrez Gene | 23586 |
Links to all GeneRIF Items | 23586 |
Links to iHOP | 23586 |
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>23586 : length: 2778 atgaccaccgagcagcgacgcagcctgcaagccttccaggattatatccggaagaccctg gaccctacctacatcctgagctacatggccccctggtttagggaggaagaggtgcagtat attcaggctgagaaaaacaacaagggcccaatggaggctgccacactttttctcaagttc ctgttggagctccaggaggaaggctggttccgtggctttttggatgccctagaccatgca ggttattctggactttatgaagccattgaaagttgggatttcaaaaaaattgaaaagttg gaggagtatagattacttttaaaacgtttacaaccagaatttaaaaccagaattatccca accgatatcatttctgatctgtctgaatgtttaattaatcaggaatgtgaagaaattcta cagatttgctctactaaggggatgatggcaggtgcagagaaattggtggaatgccttctc agatcagacaaggaaaactggcccaaaactttgaaacttgctttggagaaagaaaggaac aagttcagtgaactgtggattgtagagaaaggtataaaagatgttgaaacagaagatctt gaggataagatggaaacttctgacatacagattttctaccaagaagatccagaatgccag aatcttagtgagaattcatgtccaccttcagaagtgtctgatacaaacttgtacagccca tttaaaccaagaaattaccaattagagcttgctttgcctgctatgaaaggaaaaaacaca ataatatgtgctcctacaggttgtggaaaaacctttgtttcactgcttatatgtgaacat catcttaaaaaattcccacaaggacaaaaggggaaagttgtcttttttgcgaatcagatc ccagtgtatgaacagcagaaatctgtattctcaaaatactttgaaagacatgggtataga gttacaggcatttctggagcaacagctgagaatgtcccagtggaacagattgttgagaac aatgacatcatcattttaactccacagattcttgtgaacaaccttaaaaagggaacgatt ccatcactatccatctttactttgatgatatttgatgaatgccacaacactagtaaacaa cacccgtacaatatgatcatgtttaattatctagatcagaaacttggaggatcttcaggc ccactgccccaggtcattgggctgactgcctcggttggtgttggggatgccaaaaacaca gatgaagccttggattatatctgcaagctgtgtgcttctcttgatgcgtcagtgatagca acagtcaaacacaatctggaggaactggagcaagttgtttataagccccagaagtttttc aggaaagtggaatcacggattagcgacaaatttaaatacatcatagctcagctgatgagg gacacagagagtctggcaaagagaatctgcaaagacctcgaaaacttatctcaaattcaa aatagggaatttggaacacagaaatatgaacaatggattgttacagttcagaaagcatgc atggtgttccagatgccagacaaagatgaagagagcaggatttgtaaagccctgttttta tacacttcacatttgcggaaatataatgatgccctcattatcagtgagcatgcacgaatg aaagatgctctggattacttgaaagacttcttcagcaatgtccgagcagcaggattcgat gagattgagcaagatcttactcagagatttgaagaaaagctgcaggaactagaaagtgtt tccagggatcccagcaatgagaatcctaaacttgaagacctctgcttcatcttacaagaa gagtaccacttaaacccagagacaataacaattctctttgtgaaaaccagagcacttgtg gacgctttaaaaaattggattgaaggaaatcctaaactcagttttctaaaacctggcata ttgactggacgtggcaaaacaaatcagaacacaggaatgaccctcccggcacagaagtgt atattggatgcattcaaagccagtggagatcacaatattctgattgccacctcagttgct gatgaaggcattgacattgcacagtgcaatcttgtcatcctttatgagtatgtgggcaat gtcatcaaaatgatccaaaccagaggcagaggaagagcaagaggtagcaagtgcttcctt ctgactagtaatgctggtgtaattgaaaaagaacaaataaacatgtacaaagaaaaaatg atgaatgactctattttacgccttcagacatgggacgaagcagtatttagggaaaagatt ctgcatatacagactcatgaaaaattcatcagagatagtcaagaaaaaccaaaacctgta cctgataaggaaaataaaaaactgctctgcagaaagtgcaaagccttggcatgttacaca gctgacgtaagagtgatagaggaatgccattacactgtgcttggagatgcttttaaggaa tgctttgtgagtagaccacatcccaagccaaagcagttttcaagttttgaaaaaagagca aagatattctgtgcccgacagaactgcagccatgactggggaatccatgtgaagtacaag acatttgagattccagttataaaaattgaaagttttgtggtggaggatattgcaactgga gttcagacactgtactcgaagtggaaggactttcattttgagaagataccatttgatcca gcagaaatgtccaaatga |
Protein Sequence |
>23586 : length: 925 MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMEAATLFLKF LLELQEEGWFRGFLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIP TDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERN KFSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPECQNLSENSCPPSEVSDTNLYSP FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQI PVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTI PSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNT DEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMR DTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFL YTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELESV SRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGI LTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGN VIKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKI LHIQTHEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKE CFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG VQTLYSKWKDFHFEKIPFDPAEMSK |