| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 246 |
Name | ALOX15 |
Synonym | 12-LOX|15-LOX-1|15LOX-1;arachidonate 15-lipoxygenase;ALOX15;arachidonate 15-lipoxygenase |
Definition | 12/15-lipoxygenase|15-LOX|15-lipooxygenase-1|arachidonate 12-lipoxygenase, leukocyte-type|arachidonate omega-6 lipoxygenase |
Position | 17p13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 2684 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Linoleic acid metabolism;KEGG PATHWAY;hsa00591 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Arachidonic acid metabolism;KEGG PATHWAY;hsa00590 |
Disease | bone density;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | Osteoporosis;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | Alzheimer's disease;FunDO |
Disease | Atherosclerosis;FunDO |
|
External Links |
|
Links to Entrez Gene | 246 |
Links to all GeneRIF Items | 246 |
Links to iHOP | 246 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>246 : length: 1989 atgggtctctaccgcatccgcgtgtccactggggcctcgctctatgccggttccaacaac caggtgcagctgtggctggtcggccagcacggggaggcggcgctcgggaagcgactgtgg cccgcacggggcaaggagacagaactcaaggtggaagtaccggagtatctggggccgctg ctgtttgtgaaactgcgcaaacggcacctccttaaggacgacgcctggttctgcaactgg atctctgtgcagggccccggagccggggacgaggtcaggttcccttgttaccgctgggtg gagggcaacggcgtcctgagcctgcctgaaggcaccggccgcactgtgggcgaggaccct cagggcctgttccagaaacaccgggaagaagagctggaagagagaaggaagttgtaccgg tggggaaactggaaggacgggttaattctgaatatggctggggccaaactatatgacctc cctgtggatgagcgatttctggaagacaagagagttgactttgaggtttcgctggccaag gggctggccgacctcgctatcaaagactctctaaatgttctgacttgctggaaggatcta gatgacttcaaccggattttctggtgtggtcagagcaagctggctgagcgcgtgcgggac tcctggaaggaagatgccttatttgggtaccagtttcttaatggcgccaaccccgtggtg ctgaggcgctctgctcaccttcctgctcgcctagtgttccctccaggcatggaggaactg caggcccagctggagaaggagctggagggaggcacactgttcgaagctgacttctccctg ctggatgggatcaaggccaacgtcattctctgtagccagcagcacctggctgcccctcta gtcatgctgaaattgcagcctgatgggaaactcttgcccatggtcatccagctccagctg ccccgcacaggatccccaccacctccccttttcttgcctacggatcccccaatggcctgg cttctggccaaatgctgggtgcgcagctctgacttccagctccatgagctgcagtctcat cttctgaggggacacttgatggctgaggtcattgttgtggccaccatgaggtgcctgccg tcgatacatcctatcttcaagcttataattccccacctgcgatacaccctggaaattaac gtccgggccaggactgggctggtctctgacatgggaattttcgaccagataatgagcact ggtgggggaggccacgtgcagctgctcaagcaagctggagccttcctaacctacagctcc ttctgtccccctgatgacttggccgaccgggggctcctgggagtgaagtcttccttctat gcccaagatgcgctgcggctctgggaaatcatctatcggtatgtggaaggaatcgtgagt ctccactataagacagacgtggctgtgaaagacgacccagagctgcagacctggtgtcga gagatcactgaaatcgggctgcaaggggcccaggaccgagggtttcctgtctctttacag gctcgggaccaggtttgccactttgtcaccatgtgtatcttcacctgcaccggccaacac gcctctgtgcacctgggccagctggactggtactcttgggtgcctaatgcaccctgcacg atgcggctgcccccgccaaccaccaaggatgcaacgctggagacagtgatggcgacactg cccaacttccaccaggcttctctccagatgtccatcacttggcagctgggcagacgccag cccgttatggtggctgtgggccagcatgaggaggagtatttttcgggccctgagcctaag gctgtgctgaagaagttcagggaggagctggctgccctggataaggaaattgagatccgg aatgcaaagctggacatgccctacgagtacctgcggcccagcgtggtggaaaacagtgtg gccatctaa |
Protein Sequence |
>246 : length: 662 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPL LFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDP QGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAK GLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVV LRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPL VMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSH LLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMST GGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVS LHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQH ASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQ PVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSV AI |