Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

246

Name

ALOX15

Synonymous

12-LOX|15-LOX-1|15LOX-1;arachidonate 15-lipoxygenase;ALOX15;arachidonate 15-lipoxygenase

Definition

12/15-lipoxygenase|15-LOX|15-lipooxygenase-1|arachidonate 12-lipoxygenase, leukocyte-type|arachidonate omega-6 lipoxygenase

Position

17p13.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for ALOX15

Transcription Factors   [Top]

Regulation From TransFac database

15-LOX-1(h) --/ PPARbeta(m.s.) (decrease of abundance)
15-LOX-1(h) --> CD36(h) (transactivation)
15-LOX-1(h) --> KRT20(h) (transactivation)
ALOX15(h) --> 15-LOX-1(h) (expression).
ALOX15(h) --> 15-LOX-1(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for ALOX15

Methylation Profile   [Top]

Chromosome

Location

Source

chr17

Promoter: 4491209 - 4493209GSE27584

chr17

Promoter: 4491209 - 4493209Agilent_014791_44K


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