| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 26524 |
Name | LATS2 |
Synonym | KPM;large tumor suppressor kinase 2;LATS2;large tumor suppressor kinase 2 |
Definition | LATS (large tumor suppressor, Drosophila) homolog 2|LATS, large tumor suppressor, homolog 2|kinase phosphorylated during mitosis protein|large tumor suppressor homolog 2|serine/threonine kinase KPM|serine/threonine-protein kinase LATS2|serine/threonine-pr |
Position | 13q12.11 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9735 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Coregulation of Androgen receptor activity;PID Curated;200038 |
Disease | Brain tumor;FunDO |
Disease | Breast cancer;FunDO |
Disease | Lung cancer;FunDO |
Disease | Prostate cancer;FunDO |
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External Links |
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Links to Entrez Gene | 26524 |
Links to all GeneRIF Items | 26524 |
Links to iHOP | 26524 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>26524 : length: 3267 atgaggccaaagacttttcctgccacgacttattctggaaatagccggcagcgactgcaa gagattcgtgaggggttaaaacagccatccaagtcttcggttcaggggctacccgcagga ccaaacagtgacacttccctggatgccaaagtcctggggagcaaagatgccaccaggcag cagcagcagatgagagccaccccaaagttcggaccttatcagaaagccttgagggaaatc agatattccttgttgccttttgctaatgaatcgggcacctctgcagctgcagaagtgaac cggcaaatgctgcaggaactggtgaacgcaggatgcgaccaggagatggctggccgagct ctcaagcagactggcagcaggagcatcgaggccgccctggagtacatcagcaagatgggc tacctggacccgaggaatgagcagattgtgcgggtcattaagcagacctccccaggaaag gggctcatgccaaccccagtgacgcggaggcccagcttcgaaggaaccggcgattcgttt gcgtcctaccaccagctgagcggtaccccctacgagggcccaagcttcggcgctgacggc cccacggcgctggaggagatgccgcggccgtacgtggactaccttttccccggagtcggc ccccacgggcccggccaccagcaccagcacccacccaagggctacggtgccagcgtagag gcagcaggggcacacttcccgctgcagggcgcgcactacgggcggccgcacctgctggtg cctggggaacccctgggctacggagtgcagcgcagcccctccttccagagcaagacgccg ccggagaccgggggttacgccagcctgcccacgaagggccagggaggaccgccaggcgcc ggcctcgctttcccaccccctgccgccgggctctacgtgccgcacccacaccacaagcag gccggtcccgcggcccaccagctgcatgtgctgggctcccgcagccaggtgttcgccagc gacagccccccgcagagcctgctcactccctcgcggaacagcctcaacgtggacctgtat gaattgggcagcacctccgtccagcagtggccggctgccaccctggcccgccgggactcc ctgcagaagccgggcctggaggcgccgccgcgcgcgcacgtggccttccggcctgactgc ccagtgcccagcaggaccaactccttcaacagccaccagccgcggcccggtccgcctggc aaggccgagccctccctgcccgcccccaacaccgtgacggctgtcacggccgcgcacatc ttgcacccggtgaagagcgtgcgtgtgctgaggccggagccgcagacggctgtggggccc tcgcaccccgcctgggtgcccgcgcctgccccggcccccgcccccgcccccgccccggct gcggagggcttggacgccaaggaggagcatgccctggcgctgggcggcgcaggcgccttc ccgctggacgtggagtacggaggcccagaccggaggtgcccgcctccgccctacccgaag cacctgctgctgcgcagcaagtcggagcagtacgacctggacagcctgtgcgcaggcatg gagcagagcctccgtgcgggccccaacgagcccgagggcggcgacaagagccgcaaaagc gccaagggggacaaaggcggaaaggataaaaagcagattcagacctctcccgttcccgtc cgcaaaaacagcagagacgaagagaagagagagtcacgcatcaagagctactcgccatac gcctttaagttcttcatggagcagcacgtggagaatgtcatcaaaacctaccagcagaag gttaaccggaggctgcagctggagcaagaaatggccaaagctggactctgtgaagctgag caggagcagatgcggaagatcctctaccagaaagagtctaattacaacaggttaaagagg gccaagatggacaagtctatgtttgtcaagatcaaaaccctggggatcggtgcctttgga gaagtgtgccttgcttgtaaggtggacactcacgccctgtacgccatgaagaccctaagg aaaaaggatgtcctgaaccggaatcaggtggcccacgtcaaggccgagagggacatcctg gccgaggcagacaatgagtgggtggtcaaactctactactccttccaagacaaagacagc ctgtactttgtgatggactacatccctggtggggacatgatgagcctgctgatccggatg gaggtcttccctgagcacctggcccggttctacatcgcagagctgactttggccattgag agtgtccacaagatgggcttcatccaccgagacatcaagcctgataacattttgatagat ctggatggtcacattaaactcacagatttcggcctctgcactgggttcaggtggactcac aattccaaatattaccagaaagggagccatgtcagacaggacagcatggagcccagcgac ctctgggatgatgtgtctaactgtcggtgtggggacaggctgaagaccctagagcagagg gcgcggaagcagcaccagaggtgcctggcacattcactggtggggactccaaactacatc gcacccgaggtgctcctccgcaaagggtacactcaactctgtgactggtggagtgttgga gtgattctcttcgagatgctggtggggcagccgccctttttggcacctactcccacagaa acccagctgaaggtgatcaactgggagaacacgctccacattccagcccaggtgaagctg agccctgaggccagggacctcatcaccaagctgtgctgctccgcagaccaccgcctgggg cggaatggggccgatgacctgaaggcccaccccttcttcagcgccattgacttctccagt gacatccggaagcagccagccccctacgttcccaccatcagccaccccatggacacctcg aatttcgaccccgtagatgaagaaagcccttggaacgatgccagcgaaggtagcaccaag gcctgggacacactcacctcgcccaataacaagcatcctgagcacgcattttacgaattc accttccgaaggttctttgatgacaatggctacccctttcgatgcccaaagccttcagga gcagaagcttcacaggctgagagctcagatttagaaagctctgatctggtggatcagact gaaggctgccagcctgtgtacgtgtag |
Protein Sequence |
>26524 : length: 1088 MRPKTFPATTYSGNSRQRLQEIREGLKQPSKSSVQGLPAGPNSDTSLDAKVLGSKDATRQ QQQMRATPKFGPYQKALREIRYSLLPFANESGTSAAAEVNRQMLQELVNAGCDQEMAGRA LKQTGSRSIEAALEYISKMGYLDPRNEQIVRVIKQTSPGKGLMPTPVTRRPSFEGTGDSF ASYHQLSGTPYEGPSFGADGPTALEEMPRPYVDYLFPGVGPHGPGHQHQHPPKGYGASVE AAGAHFPLQGAHYGRPHLLVPGEPLGYGVQRSPSFQSKTPPETGGYASLPTKGQGGPPGA GLAFPPPAAGLYVPHPHHKQAGPAAHQLHVLGSRSQVFASDSPPQSLLTPSRNSLNVDLY ELGSTSVQQWPAATLARRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFNSHQPRPGPPG KAEPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPA AEGLDAKEEHALALGGAGAFPLDVEYGGPDRRCPPPPYPKHLLLRSKSEQYDLDSLCAGM EQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKSYSPY AFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR AKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDIL AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSD LWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG VILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLG RNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTK AWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAESSDLESSDLVDQT EGCQPVYV |