Entrez Gene

Basic Information
Gene ID	26524
Name	LATS2
Synonymous	KPM;large tumor suppressor kinase 2;LATS2;large tumor suppressor kinase 2
Definition	LATS (large tumor suppressor, Drosophila) homolog 2\|LATS, large tumor suppressor, homolog 2\|kinase phosphorylated during mitosis protein\|large tumor suppressor homolog 2\|serine/threonine kinase KPM\|serine/threonine-protein kinase LATS2\|serine/threonine-pr
Position	13q12.11
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
Lats2(h) + ATP --Aurora-A(h){p}--> Lats2(h){pS83} + ADP (phosphorylation)
Lats2(h) + ATP --Aurora-B(h)--> Lats2(h){pS83} + ADP (phosphorylation)
Lats2(h) + ATP --Aurora-C(h)--> Lats2(h){pS83} + ADP (phosphorylation)
Aurora-A(h) + Lats2(h) <==> Aurora-A(h):Lats2(h) (binding)
LATS2(h) --> Lats2(h) (expression).
LATS2(h) --> LATS2(h) (expression).
hsa-miR-372 --/ LATS2(h) (increase of mRNA decay).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
83	Phosphoserine (by STK6).		Swiss-Prot 53.0
83	Phosphoserine (Aurora A)	15147269	Phospho.ELM 6.0