| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 2903 |
Name | GRIN2A |
Synonym | EPND|FESD|GluN2A|LKS|NMDAR2A|NR2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A;GRIN2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
Definition | N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate receptor ionotropic, NMDA 2A |
Position | 16p13.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 8056 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Metabotropic glutamate receptor group III pathway;PANTHER;P00039 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042 |
Pathway | Reelin signaling pathway;PID Curated;200051 |
Pathway | Amyotrophic lateral sclerosis (ALS);KEGG PATHWAY;hsa05014 |
Pathway | Ionotropic glutamate receptor pathway;PANTHER;P00037 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Systemic lupus erythematosus;KEGG PATHWAY;hsa05322 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Metabotropic glutamate receptor group I pathway;PANTHER;P00041 |
Disease | schizophrenia;GAD |
Disease | PSYCH;GAD |
Disease | smoking cessation;GAD |
Disease | CHEMDEPENDENCY;GAD |
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External Links |
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Links to Entrez Gene | 2903 |
Links to all GeneRIF Items | 2903 |
Links to iHOP | 2903 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2903 : length: 4395 atgggcagagtgggctattggaccctgctggtgctgccggcccttctggtctggcgcggt ccggcgccgagcgcggcggcggagaagggtccccccgcgctaaatattgcggtgatgctg ggtcacagccacgacgtgacagagcgcgaacttcgaacactgtggggccccgagcaggcg gcggggctgcccctggacgtgaacgtggtagctctgctgatgaaccgcaccgaccccaag agcctcatcacgcacgtgtgcgacctcatgtccggggcacgcatccacggcctcgtgttt ggggacgacacggaccaggaggccgtagcccagatgctggattttatctcctcccacacc ttcgtccccatcttgggcattcatgggggcgcatctatgatcatggctgacaaggatccg acgtctaccttcttccagtttggagcgtccatccagcagcaagccacggtcatgctgaag atcatgcaggattatgactggcatgtcttctccctggtgaccactatcttccctggctac agggaattcatcagcttcgtcaagaccacagtggacaacagctttgtgggctgggacatg cagaatgtgatcacactggacacttcctttgaggatgcaaagacacaagtccagctgaag aagatccactcttctgtcatcttgctctactgttccaaagacgaggctgttctcattctg agtgaggcccgctcccttggcctcaccgggtatgatttcttctggattgtccccagcttg gtctctgggaacacggagctcatcccaaaagagtttccatcgggactcatttctgtctcc tacgatgactgggactacagcctggaggcgagagtgagggacggcattggcatcctaacc accgctgcatcttctatgctggagaagttctcctacatccccgaggccaaggccagctgc tacgggcagatggagaggccagaggtcccgatgcacaccttgcacccatttatggtcaat gttacatgggatggcaaagacttatccttcactgaggaaggctaccaggtgcaccccagg ctggtggtgattgtgctgaacaaagaccgggaatgggaaaaggtgggcaagtgggagaac catacgctgagcctgaggcacgccgtgtggcccaggtacaagtccttctccgactgtgag ccggatgacaaccatctcagcatcgtcaccctggaggaggccccattcgtcatcgtggaa gacatagaccccctgaccgagacgtgtgtgaggaacaccgtgccatgtcggaagttcgtc aaaatcaacaattcaaccaatgaggggatgaatgtgaagaaatgctgcaaggggttctgc attgatattctgaagaagctttccagaactgtgaagtttacttacgacctctatctggtg accaatgggaagcatggcaagaaagttaacaatgtgtggaatggaatgatcggtgaagtg gtctatcaacgggcagtcatggcagttggctcgctcaccatcaatgaggaacgttctgaa gtggtggacttctctgtgccctttgtggaaacgggaatcagtgtcatggtttcaagaagt aatggcaccgtctcaccttctgcttttctagaaccattcagcgcctctgtctgggtgatg atgtttgtgatgctgctcattgtttctgccatagctgtttttgtctttgaatacttcagc cctgttggatacaacagaaacttagccaaagggaaagcaccccatgggccttcttttaca attggaaaagctatatggcttctttggggcctggtgttcaataactccgtgcctgtccag aatcctaaagggaccaccagcaagatcatggtatctgtatgggccttcttcgctgtcata ttcctggctagctacacagccaatctggctgccttcatgatccaagaggaatttgtggac caagtgaccggcctcagtgacaaaaagtttcagagacctcatgactattccccacctttt cgatttgggacagtgcctaatggaagcacggagagaaacattcggaataactatccctac atgcatcagtacatgaccaaatttaatcagaaaggagtagaggacgccttggtcagcctg aaaacggggaagctggacgctttcatctacgatgccgcagtcttgaattacaaggctggg agggatgaaggctgcaagctggtgaccatcgggagtgggtacatctttgccaccaccggt tatggaattgcccttcagaaaggctctccttggaagaggcagatcgacctggccttgctt cagtttgtgggtgatggtgagatggaggagctggagaccctgtggctcactgggatctgc cacaacgagaagaacgaggtgatgagcagccagctggacattgacaacatggcgggcgta ttctacatgctggctgccgccatggcccttagcctcatcaccttcatctgggagcacctc ttctactggaagctgcgcttctgtttcacgggcgtgtgctccgaccggcctgggttgctc ttctccatcagcaggggcatctacagctgcattcatggagtgcacattgaagaaaagaag aagtctccagacttcaatctgacgggatcccagagcaacatgttaaaactcctccggtca gccaaaaacatttccagcatgtccaacatgaactcctcaagaatggactcacccaaaaga gctgctgacttcatccaaagaggttccctcatcatggacatggtttcagataaggggaat ttgatgtactcagacaacaggtcctttcaggggaaagagagcatttttggagacaacatg aacgaactccaaacatttgtggccaaccggcagaaggataacctcaataactatgtattc cagggacaacatcctcttactctcaatgagtccaaccctaacacggtggaggtggccgtg agcacagaatccaaagcgaactctagaccccggcagctgtggaagaaatccgtggattcc atacgccaggattcactatcccagaatccagtctcccagagggatgaggcaacagcagag aataggacccactccctaaagagccctaggtatcttccagaagagatggcccactctgac atttcagaaacgtcaaatcgggccacgtgccacagggaacctgacaacagtaagaaccac aaaaccaaggacaactttaaaaggtcagtggcctccaaataccccaaggactgtagtgag gtcgagcgcacctacctgaaaaccaaatcaagctcccctagagacaagatctacactata gatggtgagaaggagcctggtttccacttagatccaccccagtttgttgaaaatgtgacc ctgcccgagaacgtggacttcccggacccctaccaggatcccagtgaaaacttccgcaag ggggactccacgctgccaatgaaccggaaccccttgcataatgaagaggggctttccaac aacgaccagtataaactctactccaagcacttcaccttgaaagacaagggttccccgcac agtgagaccagcgagcgataccggcagaactccacgcactgcagaagctgcctttccaac atgcccacctattcaggccacttcaccatgaggtcccccttcaagtgcgatgcctgcctg cggatggggaacctctatgacatcgatgaagaccagatgcttcaggagacaggtaaccca gccaccggggagcaggtctaccagcaggactgggcacagaacaatgcccttcaattacaa aagaacaagctaaggattagccgtcagcattcctacgataacattgtcgacaaacctagg gagctagaccttagcaggccctcccggagcataagcctcaaggacagggaacggcttctg gagggaaatttttacggcagcctgtttagtgtcccctcaagcaaactctcggggaaaaaa agctcccttttcccccaaggtctggaggacagcaagaggagcaagtctctcttgccagac cacacctccgataaccctttcctccactcccacagggatgaccaacgcttggttattggg agatgcccctcggacccttacaaacactcgttgccatcccaggcggtgaatgacagctat cttcggtcgtccttgaggtcaacggcatcgtactgttccagggacagtcggggccacaat gatgtgtatatttcggagcatgttatgccttatgctgcaaataagaataatatgtactct acccccagggttttaaattcctgcagcaatagacgcgtgtacaagaaaatgcctagtatc gaatctgatgtttaa |
Protein Sequence |
>2903 : length: 1464 MGRVGYWTLLVLPALLVWRGPAPSAAAEKGPPALNIAVMLGHSHDVTERELRTLWGPEQA AGLPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSHT FVPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGY REFISFVKTTVDNSFVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLIL SEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGIGILT TAASSMLEKFSYIPEAKASCYGQMERPEVPMHTLHPFMVNVTWDGKDLSFTEEGYQVHPR LVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVE DIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLV TNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRS NGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFT IGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVD QVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSL KTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALL QFVGDGEMEELETLWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHL FYWKLRFCFTGVCSDRPGLLFSISRGIYSCIHGVHIEEKKKSPDFNLTGSQSNMLKLLRS AKNISSMSNMNSSRMDSPKRAADFIQRGSLIMDMVSDKGNLMYSDNRSFQGKESIFGDNM NELQTFVANRQKDNLNNYVFQGQHPLTLNESNPNTVEVAVSTESKANSRPRQLWKKSVDS IRQDSLSQNPVSQRDEATAENRTHSLKSPRYLPEEMAHSDISETSNRATCHREPDNSKNH KTKDNFKRSVASKYPKDCSEVERTYLKTKSSSPRDKIYTIDGEKEPGFHLDPPQFVENVT LPENVDFPDPYQDPSENFRKGDSTLPMNRNPLHNEEGLSNNDQYKLYSKHFTLKDKGSPH SETSERYRQNSTHCRSCLSNMPTYSGHFTMRSPFKCDACLRMGNLYDIDEDQMLQETGNP ATGEQVYQQDWAQNNALQLQKNKLRISRQHSYDNIVDKPRELDLSRPSRSISLKDRERLL EGNFYGSLFSVPSSKLSGKKSSLFPQGLEDSKRSKSLLPDHTSDNPFLHSHRDDQRLVIG RCPSDPYKHSLPSQAVNDSYLRSSLRSTASYCSRDSRGHNDVYISEHVMPYAANKNNMYS TPRVLNSCSNRRVYKKMPSIESDV |