Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2903

Name

GRIN2A

Synonymous

EPND|FESD|GluN2A|LKS|NMDAR2A|NR2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A;GRIN2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Definition

N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate receptor ionotropic, NMDA 2A

Position

16p13.2

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

huntingtin(h) + NR2A(h) <==> huntingtin(h):NR2A(h) (binding)
GRIN2A(h) --> NR2A(h) (expression).
NR2A(h) + NR1-isoform3(h) <==> NR2A(h):NR1-isoform3(h) (binding)
NR2A(h) + PSD-95beta(h) <==> NR2A(h):PSD-95beta(h) (binding)
NR2A(h) + SAP102(h) <==> NR2A(h):SAP102(h) (binding)
NR2A(h) + SAP97-isoform2(h) <==> NR2A(h):SAP97-isoform2(h) (binding)
NR2A(h) + PSD93(h) <==> NR2A(h):PSD93(h) (binding)
NR2A(h) + Cipp-isoform4(h) <==> NR2A(h):Cipp-isoform4(h) (binding)
NR2A(h) + PDLIM2-isoform1(h) <==> NR2A(h):PDLIM2-isoform1(h) (binding)
NR2A(h) + Alpha1-syntrophin(h) <==> NR2A(h):Alpha1-syntrophin(h) (binding)
NR2A(h) + Beta1-syntrophin(h) <==> NR2A(h):Beta1-syntrophin(h) (binding)
NR2A(h) + TIP1(h) <==> NR2A(h):TIP1(h) (binding)
NR2A(h) + GIPC1(h) <==> NR2A(h):GIPC1(h) (binding)
NR2A(h) + MAGI-2(h) <==> NR2A(h):MAGI-2(h) (binding)
NR1(h) + NR2A(h) <==> NR1(h):NR2A(h) (binding)
GRIN2A(h) --> NR2A(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

75N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
340N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
380N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
443N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
444N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
541N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
888Phosphothreonine (By similarity).Swiss-Prot 53.0
917Phosphoserine (By similarity).Swiss-Prot 53.0
929Phosphoserine (By similarity).Swiss-Prot 53.0
1025Phosphoserine (By similarity).Swiss-Prot 53.0
1337Phosphoserine.Swiss-Prot 53.0
1459Phosphoserine (By similarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr16

Promoter: 10183612 - 10185612Agilent_014791

chr16

Promoter: 10183612 - 10185612GSE27584


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