Entrez Gene

Basic Information
Gene ID	2903
Name	GRIN2A
Synonymous	glutamate receptor, ionotropic, N-methyl D-aspartate 2A;GRIN2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Definition	N-methyl D-aspartate receptor subtype 2A\|N-methyl-D-aspartate receptor channel, subunit epsilon-1\|N-methyl-D-aspartate receptor subunit 2A\|glutamate receptor ionotropic, NMDA 2A
Position	16p13.2
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.08.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.3909C>T; p.D1303D; 16:9763635-9763635	skin	malignant_melanoma	Substitution - coding silent
c.1231C>A; p.L411M; 16:9849853-9849853	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3026G>A; p.R1009K; 16:9764518-9764518	skin	malignant_melanoma	Substitution - Missense
c.3952C>T; p.R1318W; 16:9763592-9763592	skin	malignant_melanoma	Substitution - Missense
c.3765G>A; p.Q1255Q; 16:9763779-9763779	skin	malignant_melanoma	Substitution - coding silent
c.2167G>T; p.G723W; 16:9822265-9822265	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3051C>T; p.S1017S; 16:9764493-9764493	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3786C>A; p.T1262T; 16:9763758-9763758	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2759G>A; p.R920K; 16:9764785-9764785	NS	malignant_melanoma	Substitution - Missense
c.3566A>T; p.K1189M; 16:9763978-9763978	oesophagus	carcinoma	Substitution - Missense
c.904G>A; p.A302T; 16:9938062-9938062	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.904G>A; p.A302T; 16:9938062-9938062	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.3744C>T; p.I1248I; 16:9763800-9763800	skin	malignant_melanoma	Substitution - coding silent
c.3827C>T; p.A1276V; 16:9763717-9763717	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.904G>A; p.A302T; 16:9938062-9938062	pancreas	carcinoma	Substitution - Missense
c.904G>A; p.A302T; 16:9938062-9938062	stomach	adenocarcinoma	Substitution - Missense
c.3135C>T; p.S1045S; 16:9764409-9764409	skin	malignant_melanoma	Substitution - coding silent
c.2535G>T; p.L845L; 16:9768911-9768911	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3744C>T; p.I1248I; 16:9763800-9763800	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2499C>T; p.I833I; 16:9768947-9768947	skin	malignant_melanoma	Substitution - coding silent
c.3890A>T; p.D1297V; 16:9763654-9763654	pancreas	carcinoma	Substitution - Missense
c.1251C>T; p.V417V; 16:9849833-9849833	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3920C>T; p.P1307L; 16:9763624-9763624	skin	malignant_melanoma	Substitution - Missense
c.2499C>T; p.I833I; 16:9768947-9768947	skin	malignant_melanoma	Substitution - coding silent
c.2195C>T; p.A732V; 16:9798438-9798438	skin; arm	malignant_melanoma	Substitution - Missense
c.3744C>A; p.I1248I; 16:9763800-9763800	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2857G>C; p.E953Q; 16:9764687-9764687	skin	malignant_melanoma	Substitution - Missense
c.2550G>A; p.T850T; 16:9768896-9768896	prostate	carcinoma	Substitution - coding silent
c.3281A>G; p.Y1094C; 16:9764263-9764263	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2302G>T; p.G768C; 16:9798331-9798331	bone	osteosarcoma	Substitution - Missense
c.2550G>A; p.T850T; 16:9768896-9768896	breast	carcinoma	Substitution - coding silent
c.2550G>A; p.T850T; 16:9768896-9768896	skin	malignant_melanoma	Substitution - coding silent
c.487_488CA>AG; p.Q163R; 16:9938478-9938479	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3993C>A; p.V1331V; 16:9763551-9763551	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.3616C>T; p.R1206*; 16:9763928-9763928	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3070G>A; p.D1024N; 16:9764474-9764474	skin	malignant_melanoma	Substitution - Missense
c.3616C>T; p.R1206*; 16:9763928-9763928	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.2416G>A; p.E806K; 16:9769030-9769030	skin	malignant_melanoma	Substitution - Missense
c.2326G>T; p.D776Y; 16:9798307-9798307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2416G>A; p.E806K; 16:9769030-9769030	skin	malignant_melanoma	Substitution - Missense
c.3616C>T; p.R1206*; 16:9763928-9763928	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2416G>A; p.E806K; 16:9769030-9769030	skin	malignant_melanoma	Substitution - Missense
c.4215G>A; p.L1405L; 16:9763329-9763329	skin	malignant_melanoma	Substitution - coding silent
c.3596C>A; p.P1199Q; 16:9763948-9763948	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2533C>G; p.L845V; 16:9768913-9768913	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3102G>A; p.R1034R; 16:9764442-9764442	skin	malignant_melanoma	Substitution - coding silent
c.1164C>T; p.A388A; 16:9849920-9849920	prostate	carcinoma	Substitution - coding silent
c.3102G>A; p.R1034R; 16:9764442-9764442	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.262G>A; p.D88N; 16:10180150-10180150	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1022T>C; p.V341A; 16:9891086-9891086	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2178C>T; p.D726D; 16:9798455-9798455	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2962C>A; p.L988I; 16:9764582-9764582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1577T>C; p.V526A; 16:9840721-9840721	breast	carcinoma	Substitution - Missense
c.588G>T; p.V196V; 16:9938378-9938378	skin	malignant_melanoma	Substitution - coding silent
c.987C>T; p.V329V; 16:9937979-9937979	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2786C>T; p.S929F; 16:9764758-9764758	skin; mucosal	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.20G>A; p.W7*; 16:10180392-10180392	skin; neck	malignant_melanoma	Substitution - Nonsense
c.2786C>T; p.S929F; 16:9764758-9764758	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.81G>A; p.A27A; 16:10180331-10180331	skin	malignant_melanoma	Substitution - coding silent
c.1468A>T; p.N490Y; 16:9840965-9840965	central_nervous_system; brain	glioma	Substitution - Missense
c.150A>G; p.E50E; 16:10180262-10180262	skin	malignant_melanoma	Substitution - coding silent
c.1126G>A; p.G376S; 16:9849958-9849958	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3221C>T; p.P1074L; 16:9764323-9764323	skin; upper_back	malignant_melanoma	Substitution - Missense
c.3604G>A; p.E1202K; 16:9763940-9763940	skin	malignant_melanoma	Substitution - Missense
c.3987T>G; p.F1329L; 16:9763557-9763557	skin	malignant_melanoma	Substitution - Missense
c.4185G>A; p.A1395A; 16:9763359-9763359	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3333C>G; p.S1111R; 16:9764211-9764211	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2902G>C; p.A968P; 16:9764642-9764642	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1213C>A; p.H405N; 16:9849871-9849871	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3336C>A; p.S1112S; 16:9764208-9764208	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2748C>A; p.D916E; 16:9764796-9764796	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.3007G>T; p.E1003*; 16:9764537-9764537	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3361G>C; p.D1121H; 16:9764183-9764183	breast	carcinoma	Substitution - Missense
c.2326G>A; p.D776N; 16:9798307-9798307	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1690A>T; p.M564L; 16:9834192-9834192	central_nervous_system; brain	glioma	Substitution - Missense
c.3206C>T; p.T1069M; 16:9764338-9764338	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3506G>A; p.R1169Q; 16:9764038-9764038	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3206C>T; p.T1069M; 16:9764338-9764338	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3506G>A; p.R1169Q; 16:9764038-9764038	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3206C>T; p.T1069M; 16:9764338-9764338	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2135G>A; p.G712E; 16:9822297-9822297	skin; shoulder	malignant_melanoma	Substitution - Missense
c.3709G>A; p.D1237N; 16:9763835-9763835	skin	malignant_melanoma	Substitution - Missense
c.3506G>A; p.R1169Q; 16:9764038-9764038	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3169G>A; p.A1057T; 16:9764375-9764375	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3709G>A; p.D1237N; 16:9763835-9763835	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.2135G>A; p.G712E; 16:9822297-9822297	skin	malignant_melanoma	Substitution - Missense
c.3506G>A; p.R1169Q; 16:9764038-9764038	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2053G>C; p.V685L; 16:9822379-9822379	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3667A>T; p.T1223S; 16:9763877-9763877	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3011C>A; p.S1004Y; 16:9764533-9764533	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3889G>A; p.D1297N; 16:9763655-9763655	central_nervous_system; brain	glioma	Substitution - Missense
c.1514C>A; p.A505E; 16:9840784-9840784	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3033G>A; p.R1011R; 16:9764511-9764511	prostate	carcinoma	Substitution - coding silent
c.1314G>A; p.K438K; 16:9849770-9849770	ovary	other; neoplasm	Substitution - coding silent
c.2828A>G; p.Y943C; 16:9764716-9764716	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3074C>T; p.S1025L; 16:9764470-9764470	NS	malignant_melanoma	Substitution - Missense
c.3074C>T; p.S1025L; 16:9764470-9764470	skin	malignant_melanoma	Substitution - Missense
c.864G>A; p.L288L; 16:9938102-9938102	skin	malignant_melanoma	Substitution - coding silent
c.1928C>G; p.A643G; 16:9829502-9829502	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2695C>T; p.R899W; 16:9764849-9764849	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2412G>T; p.K804N; 16:9769034-9769034	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2901G>A; p.V967V; 16:9764643-9764643	skin	malignant_melanoma	Substitution - coding silent
c.1510C>T; p.R504W; 16:9840788-9840788	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1510C>T; p.R504W; 16:9840788-9840788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2041C>T; p.R681*; 16:9822391-9822391	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2041C>T; p.R681*; 16:9822391-9822391	skin	malignant_melanoma	Substitution - Nonsense
c.1702G>T; p.V568F; 16:9834180-9834180	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1959G>A; p.M653I; 16:9829471-9829471	NS	malignant_melanoma	Substitution - Missense
c.1959G>A; p.M653I; 16:9829471-9829471	skin	malignant_melanoma	Substitution - Missense
c.2232C>T; p.G744G; 16:9798401-9798401	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1213C>G; p.H405D; 16:9849871-9849871	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.3965G>A; p.G1322E; 16:9763579-9763579	skin	malignant_melanoma	Substitution - Missense
c.4298C>T; p.A1433V; 16:9763246-9763246	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2973C>T; p.S991S; 16:9764571-9764571	skin	malignant_melanoma	Substitution - coding silent
c.1959G>A; p.M653I; 16:9829471-9829471	skin; ear	malignant_melanoma	Substitution - Missense
c.3965G>A; p.G1322E; 16:9763579-9763579	skin	malignant_melanoma	Substitution - Missense
c.3965G>A; p.G1322E; 16:9763579-9763579	skin	malignant_melanoma	Substitution - Missense
c.3965G>A; p.G1322E; 16:9763579-9763579	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3394C>T; p.P1132S; 16:9764150-9764150	skin; mucosal	malignant_melanoma	Substitution - Missense
c.3394C>T; p.P1132S; 16:9764150-9764150	skin	malignant_melanoma	Substitution - Missense
c.4058G>A; p.R1353K; 16:9763486-9763486	skin	malignant_melanoma	Substitution - Missense
c.4027C>A; p.L1343I; 16:9763517-9763517	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.202A>C; p.N68H; 16:10180210-10180210	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3849G>C; p.K1283N; 16:9763695-9763695	thyroid	other; neoplasm	Substitution - Missense
c.57C>T; p.R19R; 16:10180355-10180355	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1366T>A; p.C456S; 16:9841067-9841067	oesophagus	carcinoma	Substitution - Missense
c.1757G>T; p.R586I; 16:9834125-9834125	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.96delC; p.A33fs*2; 16:10180316-10180316	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.718C>T; p.L240L; 16:9938248-9938248	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - coding silent
c.3857T>G; p.I1286S; 16:9763687-9763687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.39G>A; p.P13P; 16:10180373-10180373	liver	carcinoma	Substitution - coding silent
c.1113A>T; p.E371D; 16:9890995-9890995	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1593G>A; p.T531T; 16:9840705-9840705	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3879T>C; p.D1293D; 16:9763665-9763665	skin	malignant_melanoma	Substitution - coding silent
c.4161C>A; p.Y1387*; 16:9763383-9763383	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.3687C>A; p.T1229T; 16:9763857-9763857	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3157C>G; p.P1053A; 16:9764387-9764387	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1317C>T; p.F439F; 16:9849767-9849767	skin	malignant_melanoma	Substitution - coding silent
c.97G>A; p.A33T; 16:10180315-10180315	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1202C>A; p.P401Q; 16:9849882-9849882	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1980C>G; p.D660E; 16:9829450-9829450	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.945G>T; p.E315D; 16:9938021-9938021	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3975C>T; p.Y1325Y; 16:9763569-9763569	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.97G>A; p.A33T; 16:10180315-10180315	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3975C>T; p.Y1325Y; 16:9763569-9763569	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1438G>T; p.V480L; 16:9840995-9840995	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.1317C>T; p.F439F; 16:9849767-9849767	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1317C>T; p.F439F; 16:9849767-9849767	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1317C>T; p.F439F; 16:9849767-9849767	skin	malignant_melanoma	Substitution - coding silent
c.3347A>G; p.K1116R; 16:9764197-9764197	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.3379G>T; p.G1127C; 16:9764165-9764165	urinary_tract; bladder	carcinoma	Substitution - Missense
c.609G>A; p.V203V; 16:9938357-9938357	skin	malignant_melanoma	Substitution - coding silent
c.4032C>T; p.F1344F; 16:9763512-9763512	skin	malignant_melanoma	Substitution - coding silent
c.1151G>T; p.S384I; 16:9849933-9849933	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.609G>A; p.V203V; 16:9938357-9938357	skin	malignant_melanoma	Substitution - coding silent
c.4261G>A; p.D1421N; 16:9763283-9763283	skin; neck	malignant_melanoma	Substitution - Missense
c.2180C>T; p.A727V; 16:9798453-9798453	skin	malignant_melanoma	Substitution - Missense
c.3011C>G; p.S1004C; 16:9764533-9764533	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.4202T>G; p.L1401R; 16:9763342-9763342	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1529G>A; p.G510D; 16:9840769-9840769	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1403C>T; p.S468F; 16:9841030-9841030	skin	malignant_melanoma	Substitution - Missense
c.3433G>A; p.V1145M; 16:9764111-9764111	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1491C>A; p.I497I; 16:9840942-9840942	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1407_1408insT; p.T470fs*21; 16:9841025-9841026	breast	carcinoma	Insertion - Frameshift
c.3372G>T; p.K1124N; 16:9764172-9764172	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.273C>T; p.S91S; 16:10180139-10180139	skin	malignant_melanoma	Substitution - coding silent
c.4385C>G; p.S1462C; 16:9763159-9763159	large_intestine; rectum	malignant_melanoma	Substitution - Missense
c.2512G>A; p.E838K; 16:9768934-9768934	skin	malignant_melanoma	Substitution - Missense
c.995A>G; p.H332R; 16:9937971-9937971	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3867G>T; p.Q1289H; 16:9763677-9763677	skin	malignant_melanoma	Substitution - Missense
c.3028C>A; p.P1010T; 16:9764516-9764516	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1204G>A; p.D402N; 16:9849880-9849880	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3939C>T; p.L1313L; 16:9763605-9763605	skin	malignant_melanoma	Substitution - coding silent
c.666C>A; p.I222I; 16:9938300-9938300	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2277C>A; p.T759T; 16:9798356-9798356	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.3303C>T; p.V1101V; 16:9764241-9764241	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3303C>T; p.V1101V; 16:9764241-9764241	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2809G>A; p.D937N; 16:9764735-9764735	skin	malignant_melanoma	Substitution - Missense
c.2775C>T; p.I925I; 16:9764769-9764769	skin	malignant_melanoma	Substitution - coding silent
c.549C>T; p.F183F; 16:9938417-9938417	skin	malignant_melanoma	Substitution - coding silent
c.2972C>T; p.S991F; 16:9764572-9764572	skin	malignant_melanoma	Substitution - Missense
c.3681C>T; p.H1227H; 16:9763863-9763863	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1595G>A; p.G532E; 16:9840703-9840703	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1927G>A; p.A643T; 16:9829503-9829503	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.652C>A; p.Q218K; 16:9938314-9938314	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2302G>A; p.G768S; 16:9798331-9798331	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1774A>G; p.K592E; 16:9834108-9834108	skin; foot	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.75G>A; p.A25A; 16:10180337-10180337	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3511C>T; p.P1171S; 16:9764033-9764033	skin	malignant_melanoma	Substitution - Missense
c.1030G>A; p.D344N; 16:9891078-9891078	skin	malignant_melanoma	Substitution - Missense
c.1752C>A; p.Y584*; 16:9834130-9834130	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1030G>A; p.D344N; 16:9891078-9891078	skin	malignant_melanoma	Substitution - Missense
c.1141C>T; p.H381Y; 16:9849943-9849943	skin	malignant_melanoma	Substitution - Missense
c.3735C>A; p.L1245L; 16:9763809-9763809	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3854G>A; p.R1285K; 16:9763690-9763690	skin; arm	malignant_melanoma	Substitution - Missense
c.940C>T; p.P314S; 16:9938026-9938026	skin	malignant_melanoma	Substitution - Missense
c.3240C>T; p.H1080H; 16:9764304-9764304	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4181A>T; p.Q1394L; 16:9763363-9763363	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2057C>T; p.P686L; 16:9822375-9822375	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3045G>A; p.K1015K; 16:9764499-9764499	skin	malignant_melanoma	Substitution - coding silent
c.3045G>A; p.K1015K; 16:9764499-9764499	skin	malignant_melanoma	Substitution - coding silent
c.3424C>A; p.P1142T; 16:9764120-9764120	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4170G>A; p.S1390S; 16:9763374-9763374	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4170G>A; p.S1390S; 16:9763374-9763374	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.87G>A; p.K29K; 16:10180325-10180325	skin	malignant_melanoma	Substitution - coding silent
c.4101C>T; p.F1367F; 16:9763443-9763443	skin	malignant_melanoma	Substitution - coding silent
c.2563G>C; p.D855H; 16:9768883-9768883	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4204C>T; p.R1402W; 16:9763340-9763340	skin	malignant_melanoma	Substitution - Missense
c.1207G>A; p.D403N; 16:9849877-9849877	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.423G>T; p.T141T; 16:9938543-9938543	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - coding silent
c.3572T>C; p.F1191S; 16:9763972-9763972	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1667C>T; p.S556F; 16:9834215-9834215	skin	malignant_melanoma	Substitution - Missense
c.3572T>C; p.F1191S; 16:9763972-9763972	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4204C>T; p.R1402W; 16:9763340-9763340	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.658A>G; p.K220E; 16:9938308-9938308	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.91C>T; p.P31S; 16:10180321-10180321	skin	malignant_melanoma	Substitution - Missense
c.3457G>A; p.D1153N; 16:9764087-9764087	skin; scalp	malignant_melanoma	Substitution - Missense
c.658A>G; p.K220E; 16:9938308-9938308	liver	carcinoma	Substitution - Missense
c.3457G>A; p.D1153N; 16:9764087-9764087	skin	malignant_melanoma	Substitution - Missense
c.658A>G; p.K220E; 16:9938308-9938308	liver	carcinoma	Substitution - Missense
c.814T>C; p.F272L; 16:9938152-9938152	pancreas	carcinoma	Substitution - Missense
c.1794T>C; p.S598S; 16:9829636-9829636	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1111G>A; p.E371K; 16:9890997-9890997	skin; upper_back	malignant_melanoma	Substitution - Missense
c.2179G>A; p.A727T; 16:9798454-9798454	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3215G>A; p.R1072K; 16:9764329-9764329	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1111G>A; p.E371K; 16:9890997-9890997	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.3442C>T; p.P1148S; 16:9764102-9764102	skin	malignant_melanoma	Substitution - Missense
c.1111G>A; p.E371K; 16:9890997-9890997	skin; arm	malignant_melanoma	Substitution - Missense
c.235C>T; p.P79S; 16:10180177-10180177	skin	malignant_melanoma	Substitution - Missense
c.1135G>A; p.E379K; 16:9849949-9849949	skin	malignant_melanoma	Substitution - Missense
c.1037A>C; p.K346T; 16:9891071-9891071	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.890G>T; p.G297V; 16:9938076-9938076	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1980C>A; p.D660E; 16:9829450-9829450	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3677G>A; p.G1226D; 16:9763867-9763867	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3065G>A; p.R1022H; 16:9764479-9764479	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3169G>T; p.A1057S; 16:9764375-9764375	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3065G>A; p.R1022H; 16:9764479-9764479	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4274C>T; p.S1425L; 16:9763270-9763270	skin	malignant_melanoma	Substitution - Missense
c.1831C>T; p.L611L; 16:9829599-9829599	skin	malignant_melanoma	Substitution - coding silent
c.4274C>T; p.S1425L; 16:9763270-9763270	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4274C>T; p.S1425L; 16:9763270-9763270	skin; face	malignant_melanoma	Substitution - Missense
c.1747G>A; p.G583R; 16:9834135-9834135	skin	malignant_melanoma	Substitution - Missense
c.350C>T; p.S117F; 16:10180062-10180062	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2746G>A; p.D916N; 16:9764798-9764798	skin	malignant_melanoma	Substitution - Missense
c.1110G>A; p.R370R; 16:9890998-9890998	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2161A>C; p.K721Q; 16:9822271-9822271	skin	malignant_melanoma	Substitution - Missense
c.871A>G; p.R291G; 16:9938095-9938095	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4230G>A; p.S1410S; 16:9763314-9763314	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1425C>T; p.Y475Y; 16:9841008-9841008	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2917G>T; p.D973Y; 16:9764627-9764627	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1425C>T; p.Y475Y; 16:9841008-9841008	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1214A>G; p.H405R; 16:9849870-9849870	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1425C>T; p.Y475Y; 16:9841008-9841008	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2559C>T; p.C853C; 16:9768887-9768887	skin	malignant_melanoma	Substitution - coding silent
c.3341G>C; p.R1114T; 16:9764203-9764203	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3341G>C; p.R1114T; 16:9764203-9764203	urinary_tract; bladder	carcinoma	Substitution - Missense
c.136G>T; p.V46L; 16:10180276-10180276	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1451A>T; p.K484M; 16:9840982-9840982	skin	malignant_melanoma	Substitution - Missense
c.3356C>A; p.T1119N; 16:9764188-9764188	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1029G>A; p.W343*; 16:9891079-9891079	skin; back	malignant_melanoma	Substitution - Nonsense
c.1417T>A; p.F473I; 16:9841016-9841016	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1534C>T; p.L512F; 16:9840764-9840764	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3298G>A; p.E1100K; 16:9764246-9764246	oesophagus	carcinoma	Substitution - Missense
c.1114T>C; p.W372R; 16:9890994-9890994	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2357-9T>A; p.?; 16:9769098-9769098	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Unknown
c.1570T>G; p.F524V; 16:9840728-9840728	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2111A>G; p.Y704C; 16:9822321-9822321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2547C>A; p.F849L; 16:9768899-9768899	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3616C>A; p.R1206R; 16:9763928-9763928	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3616C>A; p.R1206R; 16:9763928-9763928	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3309C>A; p.R1103R; 16:9764235-9764235	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4096C>T; p.P1366S; 16:9763448-9763448	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3543C>T; p.N1181N; 16:9764001-9764001	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3491C>T; p.T1164M; 16:9764053-9764053	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3543C>T; p.N1181N; 16:9764001-9764001	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3491C>T; p.T1164M; 16:9764053-9764053	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3255_3261delCTTTAAA; p.N1085fs*20; 16:9764283-9764289	breast	carcinoma	Deletion - Frameshift
c.3152A>G; p.Y1051C; 16:9764392-9764392	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.390C>T; p.G130G; 16:10180022-10180022	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.4126C>A; p.R1376S; 16:9763418-9763418	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1203G>T; p.P401P; 16:9849881-9849881	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.170C>A; p.P57H; 16:10180242-10180242	skin	malignant_melanoma	Substitution - Missense
c.1248C>T; p.F416F; 16:9849836-9849836	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.199G>A; p.V67M; 16:10180213-10180213	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; polycythaemia_vera	Substitution - Missense
c.547T>A; p.F183I; 16:9938419-9938419	NS	malignant_melanoma	Substitution - Missense
c.3582A>G; p.K1194K; 16:9763962-9763962	bone; humerus	other; chondroblastoma	Substitution - coding silent
c.3617G>A; p.R1206Q; 16:9763927-9763927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.382C>G; p.H128D; 16:10180030-10180030	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2253G>A; p.G751G; 16:9798380-9798380	skin	malignant_melanoma	Substitution - coding silent
c.3444G>A; p.P1148P; 16:9764100-9764100	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2227G>A; p.E743K; 16:9798406-9798406	skin	malignant_melanoma	Substitution - Missense
c.144G>A; p.E48E; 16:10180268-10180268	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1996A>G; p.S666G; 16:9829434-9829434	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1249G>A; p.V417I; 16:9849835-9849835	breast	carcinoma	Substitution - Missense
c.3924C>T; p.S1308S; 16:9763620-9763620	lung	carcinoma; non_small_cell_carcinoma	Substitution - coding silent
c.3722G>A; p.R1241Q; 16:9763822-9763822	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1249G>A; p.V417I; 16:9849835-9849835	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3722G>A; p.R1241Q; 16:9763822-9763822	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1900T>A; p.W634R; 16:9829530-9829530	skin	malignant_melanoma	Substitution - Missense
c.3901G>A; p.E1301K; 16:9763643-9763643	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.329C>A; p.A110D; 16:10180083-10180083	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2458G>A; p.V820I; 16:9768988-9768988	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	skin; chest	malignant_melanoma	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	meninges	meningioma; secretory	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	skin	malignant_melanoma	Substitution - Missense
c.1585G>T; p.V529L; 16:9840713-9840713	breast	carcinoma	Substitution - Missense
c.1680G>A; p.M560I; 16:9834202-9834202	skin	malignant_melanoma	Substitution - Missense
c.2018C>A; p.P673H; 16:9822414-9822414	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1693C>A; p.L565M; 16:9834189-9834189	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2553C>T; p.G851G; 16:9768893-9768893	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2912A>G; p.Q971R; 16:9764632-9764632	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1028G>A; p.W343*; 16:9891080-9891080	skin; extremity	malignant_melanoma	Substitution - Nonsense
c.3373G>T; p.E1125*; 16:9764171-9764171	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2884G>A; p.E962K; 16:9764660-9764660	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2458G>A; p.V820I; 16:9768988-9768988	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3537C>T; p.S1179S; 16:9764007-9764007	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2140G>C; p.E714Q; 16:9822292-9822292	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2884G>A; p.E962K; 16:9764660-9764660	skin; mucosal	malignant_melanoma	Substitution - Missense
c.2996C>T; p.A999V; 16:9764548-9764548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3348G>T; p.K1116N; 16:9764196-9764196	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3109G>A; p.A1037T; 16:9764435-9764435	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2975A>C; p.N992T; 16:9764569-9764569	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4089C>T; p.S1363S; 16:9763455-9763455	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2755A>G; p.K919E; 16:9764789-9764789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.172G>A; p.E58K; 16:10180240-10180240	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4380C>T; p.I1460I; 16:9763164-9763164	skin	malignant_melanoma	Substitution - coding silent
c.4380C>T; p.I1460I; 16:9763164-9763164	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1828G>A; p.G610S; 16:9829602-9829602	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3505C>A; p.R1169R; 16:9764039-9764039	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2095C>T; p.P699S; 16:9822337-9822337	skin	malignant_melanoma	Substitution - Missense
c.2095C>T; p.P699S; 16:9822337-9822337	skin	malignant_melanoma	Substitution - Missense
c.2095C>T; p.P699S; 16:9822337-9822337	skin	malignant_melanoma	Substitution - Missense
c.2095C>T; p.P699S; 16:9822337-9822337	skin	malignant_melanoma	Substitution - Missense
c.4231T>G; p.Y1411D; 16:9763313-9763313	skin	malignant_melanoma	Substitution - Missense
c.1202C>T; p.P401L; 16:9849882-9849882	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3385C>T; p.H1129Y; 16:9764159-9764159	skin	malignant_melanoma	Substitution - Missense
c.1202C>T; p.P401L; 16:9849882-9849882	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.3385C>T; p.H1129Y; 16:9764159-9764159	skin	malignant_melanoma	Substitution - Missense
c.818C>T; p.P273L; 16:9938148-9938148	skin	malignant_melanoma	Substitution - Missense
c.1202C>T; p.P401L; 16:9849882-9849882	skin	malignant_melanoma	Substitution - Missense
c.55C>A; p.R19S; 16:10180357-10180357	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.768T>C; p.I256I; 16:9938198-9938198	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2666G>A; p.G889E; 16:9764878-9764878	skin; chest	malignant_melanoma	Substitution - Missense
c.180G>A; p.A60A; 16:10180232-10180232	skin	malignant_melanoma	Substitution - coding silent
c.3523G>A; p.E1175K; 16:9764021-9764021	skin	malignant_melanoma	Substitution - Missense
c.1420A>G; p.T474A; 16:9841013-9841013	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.716T>C; p.I239T; 16:9938250-9938250	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3474C>T; p.F1158F; 16:9764070-9764070	skin	malignant_melanoma	Substitution - coding silent
c.510C>G; p.F170L; 16:9938456-9938456	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3523G>A; p.E1175K; 16:9764021-9764021	breast	carcinoma	Substitution - Missense
c.2223G>T; p.R741S; 16:9798410-9798410	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3523G>A; p.E1175K; 16:9764021-9764021	skin	malignant_melanoma	Substitution - Missense
c.3523G>A; p.E1175K; 16:9764021-9764021	skin; upper_back	malignant_melanoma	Substitution - Missense
c.147C>T; p.R49R; 16:10180265-10180265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1462A>T; p.K488*; 16:9840971-9840971	skin	malignant_melanoma	Substitution - Nonsense
c.3868C>A; p.H1290N; 16:9763676-9763676	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1039G>T; p.D347Y; 16:9891069-9891069	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1183T>A; p.S395T; 16:9849901-9849901	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1084G>T; p.V362L; 16:9891024-9891024	liver	carcinoma	Substitution - Missense
c.510C>T; p.F170F; 16:9938456-9938456	skin	malignant_melanoma	Substitution - coding silent
c.1084G>T; p.V362L; 16:9891024-9891024	liver	carcinoma	Substitution - Missense
c.1134G>A; p.W378*; 16:9849950-9849950	skin; knee	malignant_melanoma	Substitution - Nonsense
c.963C>T; p.Y321Y; 16:9938003-9938003	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3052G>A; p.V1018M; 16:9764492-9764492	prostate	carcinoma	Substitution - Missense
c.963C>T; p.Y321Y; 16:9938003-9938003	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1912G>A; p.A638T; 16:9829518-9829518	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.316C>T; p.Q106*; 16:10180096-10180096	skin	malignant_melanoma	Substitution - Nonsense
c.3903G>A; p.E1301E; 16:9763641-9763641	skin	malignant_melanoma	Substitution - coding silent
c.1912G>A; p.A638T; 16:9829518-9829518	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2387T>A; p.L796H; 16:9769059-9769059	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3192G>A; p.T1064T; 16:9764352-9764352	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3192G>A; p.T1064T; 16:9764352-9764352	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3476G>A; p.R1159H; 16:9764068-9764068	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3476G>A; p.R1159H; 16:9764068-9764068	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4152G>A; p.S1384S; 16:9763392-9763392	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.3646A>G; p.S1216G; 16:9763898-9763898	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2276C>A; p.T759N; 16:9798357-9798357	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3827C>G; p.A1276G; 16:9763717-9763717	skin; chest	malignant_melanoma	Substitution - Missense
c.3571T>A; p.F1191I; 16:9763973-9763973	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.903C>T; p.T301T; 16:9938063-9938063	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.4249C>T; p.R1417W; 16:9763295-9763295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2816G>T; p.G939V; 16:9764728-9764728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3219A>G; p.E1073E; 16:9764325-9764325	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3484G>A; p.D1162N; 16:9764060-9764060	skin	malignant_melanoma	Substitution - Missense
c.415G>A; p.D139N; 16:9938551-9938551	skin	malignant_melanoma	Substitution - Missense
c.3080C>T; p.S1027F; 16:9764464-9764464	skin	malignant_melanoma	Substitution - Missense
c.3529G>A; p.G1177R; 16:9764015-9764015	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1275G>A; p.L425L; 16:9849809-9849809	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.415G>A; p.D139N; 16:9938551-9938551	skin	malignant_melanoma	Substitution - Missense
c.2218G>A; p.G740R; 16:9798415-9798415	NS	malignant_melanoma	Substitution - Missense
c.3943G>A; p.D1315N; 16:9763601-9763601	skin	malignant_melanoma	Substitution - Missense
c.3050C>T; p.S1017F; 16:9764494-9764494	skin	malignant_melanoma	Substitution - Missense
c.3943G>A; p.D1315N; 16:9763601-9763601	skin	malignant_melanoma	Substitution - Missense
c.1449G>A; p.G483G; 16:9840984-9840984	skin	malignant_melanoma	Substitution - coding silent
c.4385C>T; p.S1462F; 16:9763159-9763159	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.372delC; p.L125fs*9; 16:10180040-10180040	lung	carcinoma; small_cell_carcinoma	Deletion - Frameshift
c.2772C>T; p.F924F; 16:9764772-9764772	skin	malignant_melanoma	Substitution - coding silent
c.3030_3031CC>TT; p.R1011W; 16:9764513-9764514	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2668T>C; p.S890P; 16:9764876-9764876	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1240G>A; p.A414T; 16:9849844-9849844	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3789G>A; p.G1263G; 16:9763755-9763755	skin	malignant_melanoma	Substitution - coding silent
c.2083C>T; p.R695W; 16:9822349-9822349	skin	malignant_melanoma	Substitution - Missense
c.1240G>A; p.A414T; 16:9849844-9849844	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1818G>A; p.W606*; 16:9829612-9829612	breast	carcinoma	Substitution - Nonsense
c.3154C>A; p.L1052I; 16:9764390-9764390	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1161C>T; p.H387H; 16:9849923-9849923	prostate	carcinoma	Substitution - coding silent
c.3863G>A; p.R1288H; 16:9763681-9763681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4381G>A; p.E1461K; 16:9763163-9763163	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3863G>A; p.R1288H; 16:9763681-9763681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3787G>A; p.G1263R; 16:9763757-9763757	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3863G>A; p.R1288H; 16:9763681-9763681	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2964C>T; p.L988L; 16:9764580-9764580	liver	carcinoma	Substitution - coding silent
c.2563G>A; p.D855N; 16:9768883-9768883	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1667C>A; p.S556Y; 16:9834215-9834215	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2964C>T; p.L988L; 16:9764580-9764580	liver	carcinoma	Substitution - coding silent
c.3591T>G; p.G1197G; 16:9763953-9763953	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1570T>C; p.F524L; 16:9840728-9840728	pancreas	carcinoma	Substitution - Missense
c.1570T>C; p.F524L; 16:9840728-9840728	pancreas	carcinoma	Substitution - Missense
c.3000G>A; p.V1000V; 16:9764544-9764544	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1138A>G; p.N380D; 16:9849946-9849946	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1570T>C; p.F524L; 16:9840728-9840728	pancreas	carcinoma	Substitution - Missense
c.1346G>A; p.G449E; 16:9841087-9841087	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.1289T>C; p.V430A; 16:9849795-9849795	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3850C>A; p.L1284I; 16:9763694-9763694	thyroid	other; neoplasm	Substitution - Missense
c.468G>A; p.T156T; 16:9938498-9938498	skin	malignant_melanoma	Substitution - coding silent
c.468G>A; p.T156T; 16:9938498-9938498	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3595C>G; p.P1199A; 16:9763949-9763949	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2954C>T; p.P985L; 16:9764590-9764590	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.3217G>A; p.E1073K; 16:9764327-9764327	skin	malignant_melanoma	Substitution - Missense
c.135C>T; p.D45D; 16:10180277-10180277	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.832T>C; p.S278P; 16:9938134-9938134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3217G>A; p.E1073K; 16:9764327-9764327	NS	malignant_melanoma	Substitution - Missense
c.3217G>A; p.E1073K; 16:9764327-9764327	skin; ear	malignant_melanoma	Substitution - Missense
c.1981C>A; p.Q661K; 16:9829449-9829449	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1145C>T; p.T382M; 16:9849939-9849939	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2537G>A; p.R846H; 16:9768909-9768909	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3475C>T; p.R1159C; 16:9764069-9764069	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3475C>T; p.R1159C; 16:9764069-9764069	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1491C>T; p.I497I; 16:9840942-9840942	skin; arm	malignant_melanoma	Substitution - coding silent
c.2011C>T; p.Q671*; 16:9822421-9822421	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Nonsense
c.179C>T; p.A60V; 16:10180233-10180233	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2426G>A; p.S809N; 16:9769020-9769020	skin	malignant_melanoma	Substitution - Missense
c.363C>T; p.F121F; 16:10180049-10180049	skin	malignant_melanoma	Substitution - coding silent
c.4229C>T; p.S1410L; 16:9763315-9763315	skin	malignant_melanoma	Substitution - Missense
c.1532C>T; p.S511L; 16:9840766-9840766	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2671C>T; p.Q891*; 16:9764873-9764873	NS	malignant_melanoma	Substitution - Nonsense
c.179C>T; p.A60V; 16:10180233-10180233	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1532C>T; p.S511L; 16:9840766-9840766	skin; neck	malignant_melanoma	Substitution - Missense
c.363C>T; p.F121F; 16:10180049-10180049	skin	malignant_melanoma	Substitution - coding silent
c.2451G>T; p.M817I; 16:9768995-9768995	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1532C>T; p.S511L; 16:9840766-9840766	skin	malignant_melanoma	Substitution - Missense
c.3426C>T; p.P1142P; 16:9764118-9764118	skin	malignant_melanoma	Substitution - coding silent
c.3426C>T; p.P1142P; 16:9764118-9764118	skin	malignant_melanoma	Substitution - coding silent
c.2691C>T; p.L897L; 16:9764853-9764853	skin	malignant_melanoma	Substitution - coding silent
c.181G>A; p.A61T; 16:10180231-10180231	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3855G>A; p.R1285R; 16:9763689-9763689	skin	malignant_melanoma	Substitution - coding silent
c.3855G>A; p.R1285R; 16:9763689-9763689	skin	malignant_melanoma	Substitution - coding silent
c.3395C>T; p.P1132L; 16:9764149-9764149	skin; ear	malignant_melanoma	Substitution - Missense
c.2601C>A; p.I867I; 16:9764943-9764943	skin	malignant_melanoma	Substitution - coding silent
c.3395C>T; p.P1132L; 16:9764149-9764149	skin	malignant_melanoma	Substitution - Missense
c.2977C>A; p.P993T; 16:9764567-9764567	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.406G>C; p.A136P; 16:10180006-10180006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2908C>T; p.R970W; 16:9764636-9764636	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2500A>C; p.T834P; 16:9768946-9768946	breast	carcinoma	Substitution - Missense
c.754G>A; p.D252N; 16:9938212-9938212	skin	malignant_melanoma	Substitution - Missense
c.155G>A; p.R52Q; 16:10180257-10180257	skin	malignant_melanoma	Substitution - Missense
c.754G>A; p.D252N; 16:9938212-9938212	skin; arm	malignant_melanoma	Substitution - Missense
c.3876C>T; p.Y1292Y; 16:9763668-9763668	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2856A>G; p.K952K; 16:9764688-9764688	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.794C>T; p.T265M; 16:9938172-9938172	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.450C>A; p.S150S; 16:9938516-9938516	skin; arm	malignant_melanoma	Substitution - coding silent
c.4126C>T; p.R1376C; 16:9763418-9763418	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3617G>T; p.R1206L; 16:9763927-9763927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1121delA; p.K374fs*10; 16:9890987-9890987	pancreas	carcinoma; acinar_carcinoma	Deletion - Frameshift
c.4126C>T; p.R1376C; 16:9763418-9763418	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3832C>A; p.Q1278K; 16:9763712-9763712	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.99G>A; p.A33A; 16:10180313-10180313	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.99G>A; p.A33A; 16:10180313-10180313	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.99G>A; p.A33A; 16:10180313-10180313	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2946A>G; p.G982G; 16:9764598-9764598	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.880G>A; p.D294N; 16:9938086-9938086	skin	malignant_melanoma	Substitution - Missense
c.2721G>A; p.M907I; 16:9764823-9764823	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1391T>C; p.L464P; 16:9841042-9841042	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1757G>A; p.R586K; 16:9834125-9834125	skin	malignant_melanoma	Substitution - Missense
c.325G>A; p.V109I; 16:10180087-10180087	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3882C>A; p.N1294K; 16:9763662-9763662	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.817C>T; p.P273S; 16:9938149-9938149	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1572C>G; p.F524L; 16:9840726-9840726	breast	carcinoma	Substitution - Missense
c.700G>A; p.D234N; 16:9938266-9938266	skin	malignant_melanoma	Substitution - Missense
c.132C>T; p.H44H; 16:10180280-10180280	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1516G>T; p.V506F; 16:9840782-9840782	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2145C>T; p.D715D; 16:9822287-9822287	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.748G>A; p.G250R; 16:9938218-9938218	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1303C>T; p.P435S; 16:9849781-9849781	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.372C>T; p.I124I; 16:10180040-10180040	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4012G>A; p.G1338R; 16:9763532-9763532	skin	malignant_melanoma	Substitution - Missense
c.388G>T; p.G130C; 16:10180024-10180024	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.415-1G>A; p.?; 16:9938552-9938552	skin	malignant_melanoma	Unknown
c.1848C>T; p.S616S; 16:9829582-9829582	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.4071C>T; p.L1357L; 16:9763473-9763473	skin	malignant_melanoma	Substitution - coding silent
c.2558G>C; p.C853S; 16:9768888-9768888	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1472A>T; p.N491I; 16:9840961-9840961	liver	carcinoma	Substitution - Missense
c.363C>A; p.F121L; 16:10180049-10180049	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1813A>G; p.I605V; 16:9829617-9829617	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.222G>A; p.M74I; 16:10180190-10180190	skin	malignant_melanoma	Substitution - Missense
c.3918G>A; p.R1306R; 16:9763626-9763626	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2071G>A; p.E691K; 16:9822361-9822361	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3443C>T; p.P1148L; 16:9764101-9764101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3819G>A; p.Q1273Q; 16:9763725-9763725	skin	malignant_melanoma	Substitution - coding silent
c.2659C>T; p.L887L; 16:9764885-9764885	skin	malignant_melanoma	Substitution - coding silent
c.4324C>T; p.P1442S; 16:9763220-9763220	skin	malignant_melanoma	Substitution - Missense
c.3246C>T; p.T1082T; 16:9764298-9764298	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2659C>T; p.L887L; 16:9764885-9764885	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2265C>T; p.I755I; 16:9798368-9798368	skin	malignant_melanoma	Substitution - coding silent
c.252G>A; p.T84T; 16:10180160-10180160	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4355G>A; p.R1452H; 16:9763189-9763189	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.4355G>A; p.R1452H; 16:9763189-9763189	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1594G>A; p.G532R; 16:9840704-9840704	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2120A>C; p.K707T; 16:9822312-9822312	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4069C>T; p.L1357F; 16:9763475-9763475	skin	malignant_melanoma	Substitution - Missense
c.3191C>T; p.T1064M; 16:9764353-9764353	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4232A>G; p.Y1411C; 16:9763312-9763312	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3191C>T; p.T1064M; 16:9764353-9764353	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.742C>T; p.L248F; 16:9938224-9938224	skin	malignant_melanoma	Substitution - Missense
c.3346A>T; p.K1116*; 16:9764198-9764198	NS	malignant_melanoma	Substitution - Nonsense
c.59G>A; p.G20D; 16:10180353-10180353	skin	malignant_melanoma	Substitution - Missense
c.148G>A; p.E50K; 16:10180264-10180264	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.59G>A; p.G20D; 16:10180353-10180353	skin	malignant_melanoma	Substitution - Missense
c.148G>A; p.E50K; 16:10180264-10180264	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4184C>T; p.A1395V; 16:9763360-9763360	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3315C>A; p.Y1105*; 16:9764229-9764229	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2657A>G; p.N886S; 16:9764887-9764887	pancreas	carcinoma	Substitution - Missense
c.2657A>G; p.N886S; 16:9764887-9764887	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1927G>T; p.A643S; 16:9829503-9829503	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.313G>A; p.D105N; 16:10180099-10180099	skin	malignant_melanoma	Substitution - Missense
c.2657A>G; p.N886S; 16:9764887-9764887	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.2063G>A; p.G688E; 16:9822369-9822369	skin	malignant_melanoma	Substitution - Missense
c.3333C>T; p.S1111S; 16:9764211-9764211	skin	malignant_melanoma	Substitution - coding silent
c.2528G>A; p.W843*; 16:9768918-9768918	skin	malignant_melanoma	Substitution - Nonsense
c.2063G>A; p.G688E; 16:9822369-9822369	skin	malignant_melanoma	Substitution - Missense
c.1062C>A; p.G354G; 16:9891046-9891046	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3967A>T; p.N1323Y; 16:9763577-9763577	skin	malignant_melanoma	Substitution - Missense
c.2614C>A; p.H872N; 16:9764930-9764930	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3199C>T; p.R1067W; 16:9764345-9764345	skin	malignant_melanoma	Substitution - Missense
c.3199C>T; p.R1067W; 16:9764345-9764345	breast	carcinoma	Substitution - Missense
c.4021delA; p.S1341fs*56; 16:9763523-9763523	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4021delA; p.S1341fs*56; 16:9763523-9763523	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4021delA; p.S1341fs*56; 16:9763523-9763523	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3199C>T; p.R1067W; 16:9764345-9764345	skin	malignant_melanoma	Substitution - Missense
c.244C>T; p.L82F; 16:10180168-10180168	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.1299C>A; p.T433T; 16:9849785-9849785	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3555A>G; p.K1185K; 16:9763989-9763989	skin	malignant_melanoma	Substitution - coding silent
c.4021delA; p.S1341fs*56; 16:9763523-9763523	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3199C>T; p.R1067W; 16:9764345-9764345	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3199C>T; p.R1067W; 16:9764345-9764345	skin	malignant_melanoma	Substitution - Missense
c.4021delA; p.S1341fs*56; 16:9763523-9763523	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.387G>A; p.G129G; 16:10180025-10180025	skin	malignant_melanoma	Substitution - coding silent
c.4021delA; p.S1341fs*56; 16:9763523-9763523	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2814G>A; p.K938K; 16:9764730-9764730	skin	malignant_melanoma	Substitution - coding silent
c.419C>T; p.P140L; 16:9938547-9938547	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1255G>A; p.V419M; 16:9849829-9849829	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1255G>A; p.V419M; 16:9849829-9849829	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.260G>T; p.C87F; 16:10180152-10180152	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3635C>A; p.T1212K; 16:9763909-9763909	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.450C>T; p.S150S; 16:9938516-9938516	skin	malignant_melanoma	Substitution - coding silent
c.833C>T; p.S278F; 16:9938133-9938133	NS	malignant_melanoma	Substitution - Missense
c.833C>T; p.S278F; 16:9938133-9938133	skin	malignant_melanoma	Substitution - Missense
c.833C>T; p.S278F; 16:9938133-9938133	skin	malignant_melanoma	Substitution - Missense
c.2663C>T; p.T888M; 16:9764881-9764881	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2985G>A; p.T995T; 16:9764559-9764559	skin	malignant_melanoma	Substitution - coding silent
c.2278G>A; p.G760S; 16:9798355-9798355	oesophagus	carcinoma	Substitution - Missense
c.3316C>T; p.L1106L; 16:9764228-9764228	skin	malignant_melanoma	Substitution - coding silent
c.4209G>C; p.S1403S; 16:9763335-9763335	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3953G>A; p.R1318Q; 16:9763591-9763591	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4321A>G; p.T1441A; 16:9763223-9763223	liver	carcinoma	Substitution - Missense
c.4321A>G; p.T1441A; 16:9763223-9763223	liver	carcinoma	Substitution - Missense
c.676G>A; p.V226I; 16:9938290-9938290	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3618A>G; p.R1206R; 16:9763926-9763926	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3571T>C; p.F1191L; 16:9763973-9763973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3571T>C; p.F1191L; 16:9763973-9763973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3571T>C; p.F1191L; 16:9763973-9763973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3571T>C; p.F1191L; 16:9763973-9763973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2460A>T; p.V820V; 16:9768986-9768986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4014G>A; p.G1338G; 16:9763530-9763530	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1629C>T; p.T543T; 16:9840669-9840669	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.727G>T; p.A243S; 16:9938239-9938239	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1629C>T; p.T543T; 16:9840669-9840669	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4014G>A; p.G1338G; 16:9763530-9763530	skin	malignant_melanoma	Substitution - coding silent
c.3373G>A; p.E1125K; 16:9764171-9764171	skin	malignant_melanoma	Substitution - Missense
c.128G>A; p.S43N; 16:10180284-10180284	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1162G>A; p.A388T; 16:9849922-9849922	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.964G>T; p.G322W; 16:9938002-9938002	breast	carcinoma	Substitution - Missense
c.3926G>A; p.R1309Q; 16:9763618-9763618	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.315C>G; p.D105E; 16:10180097-10180097	breast	carcinoma	Substitution - Missense
c.3373G>A; p.E1125K; 16:9764171-9764171	skin	malignant_melanoma	Substitution - Missense
c.2406C>T; p.N802N; 16:9769040-9769040	liver	carcinoma	Substitution - coding silent
c.3020A>G; p.N1007S; 16:9764524-9764524	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3766G>A; p.E1256K; 16:9763778-9763778	skin; acral	malignant_melanoma	Substitution - Missense
c.1969G>A; p.E657K; 16:9829461-9829461	skin	malignant_melanoma	Substitution - Missense
c.1521G>A; p.M507I; 16:9840777-9840777	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2937A>G; p.V979V; 16:9764607-9764607	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2152G>A; p.V718I; 16:9822280-9822280	stomach	adenocarcinoma	Substitution - Missense
c.1381A>T; p.I461F; 16:9841052-9841052	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2984C>T; p.T995M; 16:9764560-9764560	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.993G>A; p.M331I; 16:9937973-9937973	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2984C>T; p.T995M; 16:9764560-9764560	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2730G>A; p.M910I; 16:9764814-9764814	skin	malignant_melanoma	Substitution - Missense
c.2861G>A; p.S954N; 16:9764683-9764683	skin; mucosal	malignant_melanoma	Substitution - Missense
c.74C>T; p.A25V; 16:10180338-10180338	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1751A>G; p.Y584C; 16:9834131-9834131	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3064C>T; p.R1022C; 16:9764480-9764480	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4171T>G; p.L1391V; 16:9763373-9763373	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4114A>C; p.R1372R; 16:9763430-9763430	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.232G>A; p.D78N; 16:10180180-10180180	skin	malignant_melanoma	Substitution - Missense
c.232G>A; p.D78N; 16:10180180-10180180	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>A; p.D78N; 16:10180180-10180180	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3625C>A; p.Q1209K; 16:9763919-9763919	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.736C>A; p.L246I; 16:9938230-9938230	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.198C>T; p.D66D; 16:10180214-10180214	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3576C>T; p.T1192T; 16:9763968-9763968	skin	malignant_melanoma	Substitution - coding silent
c.4393T>A; p.*1465K; 16:9763151-9763151	skin	malignant_melanoma	Nonstop extension
c.4371G>T; p.M1457I; 16:9763173-9763173	skin	malignant_melanoma	Substitution - Missense
c.3921C>A; p.P1307P; 16:9763623-9763623	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3474C>A; p.F1158L; 16:9764070-9764070	pleura	pulmonary_blastoma	Substitution - Missense
c.2432A>T; p.Q811L; 16:9769014-9769014	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3269T>C; p.V1090A; 16:9764275-9764275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4212C>T; p.S1404S; 16:9763332-9763332	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3452A>G; p.Y1151C; 16:9764092-9764092	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3708C>A; p.C1236*; 16:9763836-9763836	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3018G>A; p.A1006A; 16:9764526-9764526	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3018G>A; p.A1006A; 16:9764526-9764526	skin	malignant_melanoma	Substitution - coding silent
c.3018G>A; p.A1006A; 16:9764526-9764526	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3399C>A; p.P1133P; 16:9764145-9764145	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3922T>C; p.S1308P; 16:9763622-9763622	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4067C>A; p.S1356Y; 16:9763477-9763477	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2169-1G>A; p.?; 16:9798465-9798465	skin	malignant_melanoma	Unknown
c.3018G>A; p.A1006A; 16:9764526-9764526	skin	malignant_melanoma	Substitution - coding silent
c.4017A>G; p.K1339K; 16:9763527-9763527	skin	malignant_melanoma	Substitution - coding silent
c.3505C>T; p.R1169W; 16:9764039-9764039	pancreas	carcinoma	Substitution - Missense
c.2536C>A; p.R846S; 16:9768910-9768910	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1742C>T; p.P581L; 16:9834140-9834140	skin	malignant_melanoma	Substitution - Missense
c.666C>G; p.I222M; 16:9938300-9938300	breast	carcinoma	Substitution - Missense
c.2324T>C; p.I775T; 16:9798309-9798309	breast	carcinoma	Substitution - Missense
c.3355A>C; p.T1119P; 16:9764189-9764189	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1737C>T; p.F579F; 16:9834145-9834145	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.2146G>A; p.A716T; 16:9822286-9822286	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2332G>A; p.A778T; 16:9798301-9798301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1311G>A; p.R437R; 16:9849773-9849773	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2146G>A; p.A716T; 16:9822286-9822286	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1898T>C; p.V633A; 16:9829532-9829532	urinary_tract; bladder	carcinoma	Substitution - Missense
c.681C>A; p.I227I; 16:9938285-9938285	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.306C>T; p.D102D; 16:10180106-10180106	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3526G>T; p.E1176*; 16:9764018-9764018	breast	carcinoma	Substitution - Nonsense
c.657G>A; p.L219L; 16:9938309-9938309	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2075G>C; p.R692T; 16:9822357-9822357	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4276G>A; p.E1426K; 16:9763268-9763268	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.2085G>C; p.R695R; 16:9822347-9822347	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1278C>T; p.T426T; 16:9849806-9849806	skin	malignant_melanoma	Substitution - coding silent
c.2085G>C; p.R695R; 16:9822347-9822347	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1278C>T; p.T426T; 16:9849806-9849806	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1945C>T; p.L649L; 16:9829485-9829485	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2221A>G; p.R741G; 16:9798412-9798412	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4208C>T; p.S1403L; 16:9763336-9763336	skin	malignant_melanoma	Substitution - Missense
c.3176C>G; p.S1059C; 16:9764368-9764368	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1805G>A; p.G602E; 16:9829625-9829625	skin	malignant_melanoma	Substitution - Missense
c.251C>T; p.T84M; 16:10180161-10180161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3347A>C; p.K1116T; 16:9764197-9764197	breast	carcinoma	Substitution - Missense
c.4354C>T; p.R1452C; 16:9763190-9763190	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3510C>T; p.N1170N; 16:9764034-9764034	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1823T>C; p.L608P; 16:9829607-9829607	skin	malignant_melanoma	Substitution - Missense
c.1485A>T; p.G495G; 16:9840948-9840948	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3103G>A; p.D1035N; 16:9764441-9764441	skin; ear	malignant_melanoma	Substitution - Missense
c.2880G>A; p.M960I; 16:9764664-9764664	breast	carcinoma	Substitution - Missense
c.324C>T; p.A108A; 16:10180088-10180088	skin	malignant_melanoma	Substitution - coding silent
c.1787G>A; p.G596E; 16:9829643-9829643	skin	malignant_melanoma	Substitution - Missense
c.3812G>A; p.W1271*; 16:9763732-9763732	skin; foot	malignant_melanoma	Substitution - Nonsense
c.1095G>T; p.V365V; 16:9891013-9891013	thyroid	other; neoplasm	Substitution - coding silent
c.4340C>T; p.S1447F; 16:9763204-9763204	skin	malignant_melanoma	Substitution - Missense
c.965G>A; p.G322E; 16:9938001-9938001	meninges	meningioma; haemangiopericytic	Substitution - Missense
c.2191G>A; p.D731N; 16:9798442-9798442	skin	malignant_melanoma	Substitution - Missense
c.2714C>T; p.S905F; 16:9764830-9764830	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.843C>T; p.Y281Y; 16:9938123-9938123	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2203T>A; p.L735M; 16:9798430-9798430	skin	malignant_melanoma	Substitution - Missense
c.2714C>T; p.S905F; 16:9764830-9764830	skin	malignant_melanoma	Substitution - Missense
c.436C>T; p.Q146*; 16:9938530-9938530	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2452G>A; p.A818T; 16:9768994-9768994	oesophagus	carcinoma	Substitution - Missense
c.1308T>A; p.C436*; 16:9849776-9849776	liver	carcinoma	Substitution - Nonsense
c.889G>A; p.G297S; 16:9938077-9938077	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3441C>T; p.F1147F; 16:9764103-9764103	skin	malignant_melanoma	Substitution - coding silent
c.3597G>A; p.P1199P; 16:9763947-9763947	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3597G>A; p.P1199P; 16:9763947-9763947	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3441C>T; p.F1147F; 16:9764103-9764103	skin	malignant_melanoma	Substitution - coding silent
c.3367G>T; p.E1123*; 16:9764177-9764177	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3597G>A; p.P1199P; 16:9763947-9763947	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3120G>T; p.E1040D; 16:9764424-9764424	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1472A>G; p.N491S; 16:9840961-9840961	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1923C>T; p.F641F; 16:9829507-9829507	skin	malignant_melanoma	Substitution - coding silent
c.2355T>C; p.D785D; 16:9798278-9798278	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3248A>C; p.K1083T; 16:9764296-9764296	skin	malignant_melanoma	Substitution - Missense
c.1165G>A; p.V389M; 16:9849919-9849919	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.3220C>T; p.P1074S; 16:9764324-9764324	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1592C>T; p.T531M; 16:9840706-9840706	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2067C>T; p.S689S; 16:9822365-9822365	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3284C>A; p.P1095H; 16:9764260-9764260	breast	carcinoma	Substitution - Missense
c.920T>A; p.L307Q; 16:9938046-9938046	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4097C>T; p.P1366L; 16:9763447-9763447	skin; ear	malignant_melanoma	Substitution - Missense
c.3593C>T; p.S1198F; 16:9763951-9763951	skin	malignant_melanoma	Substitution - Missense
c.3444G>T; p.P1148P; 16:9764100-9764100	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3227A>G; p.N1076S; 16:9764317-9764317	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1778-8T>C; p.?; 16:9829660-9829660	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.111G>A; p.A37A; 16:10180301-10180301	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1983A>C; p.Q661H; 16:9829447-9829447	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1849G>T; p.V617L; 16:9829581-9829581	thyroid	carcinoma	Substitution - Missense
c.3145C>A; p.P1049T; 16:9764399-9764399	liver	carcinoma	Substitution - Missense
c.1087G>T; p.V363L; 16:9891021-9891021	prostate	carcinoma	Substitution - Missense
c.2415C>T; p.N805N; 16:9769031-9769031	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2415C>T; p.N805N; 16:9769031-9769031	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2549C>T; p.T850M; 16:9768897-9768897	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3534T>G; p.L1178L; 16:9764010-9764010	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3686C>T; p.T1229I; 16:9763858-9763858	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2883C>T; p.N961N; 16:9764661-9764661	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2616T>A; p.H872Q; 16:9764928-9764928	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1279G>A; p.E427K; 16:9849805-9849805	skin	malignant_melanoma	Substitution - Missense
c.4048G>A; p.D1350N; 16:9763496-9763496	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4048G>A; p.D1350N; 16:9763496-9763496	skin	malignant_melanoma	Substitution - Missense
c.1655C>T; p.P552L; 16:9834227-9834227	skin	malignant_melanoma	Substitution - Missense
c.1376T>C; p.F459S; 16:9841057-9841057	skin	malignant_melanoma	Substitution - Missense
c.1864C>T; p.P622S; 16:9829566-9829566	skin	malignant_melanoma	Substitution - Missense
c.3466G>A; p.E1156K; 16:9764078-9764078	skin	malignant_melanoma	Substitution - Missense
c.3466G>A; p.E1156K; 16:9764078-9764078	skin	malignant_melanoma	Substitution - Missense
c.154C>T; p.R52*; 16:10180258-10180258	skin; ear	malignant_melanoma	Substitution - Nonsense
c.4334T>G; p.L1445*; 16:9763210-9763210	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4169C>T; p.S1390L; 16:9763375-9763375	skin	malignant_melanoma	Substitution - Missense
c.1794T>G; p.S598S; 16:9829636-9829636	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1225G>A; p.V409I; 16:9849859-9849859	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4169C>T; p.S1390L; 16:9763375-9763375	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1359G>T; p.K453N; 16:9841074-9841074	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.340G>A; p.D114N; 16:10180072-10180072	skin	malignant_melanoma	Substitution - Missense
c.1794T>G; p.S598S; 16:9829636-9829636	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3808G>C; p.D1270H; 16:9763736-9763736	skin	malignant_melanoma	Substitution - Missense
c.1793C>T; p.S598F; 16:9829637-9829637	skin	malignant_melanoma	Substitution - Missense
c.1172C>G; p.P391R; 16:9849912-9849912	ovary	other; neoplasm	Substitution - Missense
c.3041G>T; p.W1014L; 16:9764503-9764503	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4317C>A; p.Y1439*; 16:9763227-9763227	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4071C>A; p.L1357L; 16:9763473-9763473	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3728G>T; p.G1243V; 16:9763816-9763816	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2393G>T; p.G798V; 16:9769053-9769053	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.3338C>T; p.P1113L; 16:9764206-9764206	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3862C>T; p.R1288C; 16:9763682-9763682	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.3862C>T; p.R1288C; 16:9763682-9763682	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3862C>T; p.R1288C; 16:9763682-9763682	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3728G>T; p.G1243V; 16:9763816-9763816	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.926A>C; p.K309T; 16:9938040-9938040	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1593G>T; p.T531T; 16:9840705-9840705	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1040A>C; p.D347A; 16:9891068-9891068	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.926A>C; p.K309T; 16:9938040-9938040	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3708C>T; p.C1236C; 16:9763836-9763836	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1384G>A; p.D462N; 16:9841049-9841049	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.423G>A; p.T141T; 16:9938543-9938543	pancreas	carcinoma	Substitution - coding silent
c.1384G>A; p.D462N; 16:9841049-9841049	skin	malignant_melanoma	Substitution - Missense
c.3708C>T; p.C1236C; 16:9763836-9763836	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2115G>C; p.M705I; 16:9822317-9822317	urinary_tract; bladder	carcinoma	Substitution - Missense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]