| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3579 |
Name | CXCR2 |
Synonym | CD182|CDw128b|CMKAR2|IL8R2|IL8RA|IL8RB;chemokine (C-X-C motif) receptor 2;CXCR2;chemokine (C-X-C motif) receptor 2 |
Definition | C-X-C chemokine receptor type 2|CXC-R2|CXCR-2|CXCR2 gene for IL8 receptor type B|GRO/MGSA receptor|IL-8 receptor type 2|IL-8R B|chemokine (CXC) receptor 2|high affinity interleukin-8 receptor B|interleukin 8 receptor B|interleukin 8 receptor type 2|interl |
Position | 2q35 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 5574 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Epithelial cell signaling in Helicobacter pylori infection;KEGG PATHWAY;hsa05120 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Chemokine receptors bind chemokines;PID Reactome;500406 |
Disease | Lupus erythematosus;FunDO |
Disease | Common cold;FunDO |
Disease | Amnionitis;FunDO |
Disease | tuberculosis;GAD |
Disease | IMMUNE;GAD |
Disease | hematology indices;GAD |
Disease | Polycystic kidney;FunDO |
Disease | Multiple sclerosis;FunDO |
Disease | Melanoma;FunDO |
Disease | Arthritis;FunDO |
Disease | herpesvirus, Kaposi sarcoma-associated;GAD |
Disease | INFECTION;GAD |
Disease | Endometriosis;FunDO |
Disease | Colon cancer;FunDO |
Disease | Myeloid metaplasia;FunDO |
Disease | Myelofibrosis;FunDO |
Disease | Peptic esophagitis;FunDO |
|
External Links |
|
Links to Entrez Gene | 3579 |
Links to all GeneRIF Items | 3579 |
Links to iHOP | 3579 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3579 : length: 1083 atggaagattttaacatggagagtgacagctttgaagatttctggaaaggtgaagatctt agtaattacagttacagctctaccctgcccccttttctactagatgccgccccatgtgaa ccagaatccctggaaatcaacaagtattttgtggtcattatctatgccctggtattcctg ctgagcctgctgggaaactccctcgtgatgctggtcatcttatacagcagggtcggccgc tccgtcactgatgtctacctgctgaacctagccttggccgacctactctttgccctgacc ttgcccatctgggccgcctccaaggtgaatggctggatttttggcacattcctgtgcaag gtggtctcactcctgaaggaagtcaacttctatagtggcatcctgctactggcctgcatc agtgtggaccgttacctggccattgtccatgccacacgcacactgacccagaagcgctac ttggtcaaattcatatgtctcagcatctggggtctgtccttgctcctggccctgcctgtc ttacttttccgaaggaccgtctactcatccaatgttagcccagcctgctatgaggacatg ggcaacaatacagcaaactggcggatgctgttacggatcctgccccagtcctttggcttc atcgtgccactgctgatcatgctgttctgctacggattcaccctgcgtacgctgtttaag gcccacatggggcagaagcaccgggccatgcgggtcatctttgctgtcgtcctcatcttc ctgctctgctggctgccctacaacctggtcctgctggcagacaccctcatgaggacccag gtgatccaggagacctgtgagcgccgcaatcacatcgaccgggctctggatgccaccgag attctgggcatccttcacagctgcctcaaccccctcatctacgccttcattggccagaag tttcgccatggactcctcaagattctagctatacatggcttgatcagcaaggactccctg cccaaagacagcaggccttcctttgttggctcttcttcagggcacacttccactactctc taa |
Protein Sequence |
>3579 : length: 360 MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFL LSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCK VVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPV LLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFK AHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATE ILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL |