| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3611 |
Name | ILK |
Synonym | HEL-S-28|ILK-1|ILK-2|P59|p59ILK;integrin-linked kinase;ILK;integrin-linked kinase |
Definition | 59 kDa serine/threonine-protein kinase|epididymis secretory protein Li 28|integrin-linked kinase-2|integrin-linked protein kinase |
Position | 11p15.4 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 8922 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | pten dependent cell cycle arrest and apoptosis;PID BioCarta;100058 |
Pathway | Cell-extracellular matrix interactions;PID Reactome;500123 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | Localization of the PINCH-ILK-PARVIN complex to focal adhesions;PID Reactome;500124 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | PPAR signaling pathway;KEGG PATHWAY;hsa03320 |
Disease | Cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 3611 |
Links to all GeneRIF Items | 3611 |
Links to iHOP | 3611 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3611 : length: 1359 atggacgacattttcactcagtgccgggagggcaacgcagtcgccgttcgcctgtggctg gacaacacggagaacgacctcaaccagggggacgatcatggcttctcccccttgcactgg gcctgccgagagggccgctctgctgtggttgagatgttgatcatgcggggggcacggatc aatgtaatgaaccgtggggatgacacccccctgcatctggcagccagtcatggacaccgt gatattgtacagaagctattgcagtacaaggcagacatcaatgcagtgaatgaacacggg aatgtgcccctgcactatgcctgtttttggggccaagatcaagtggcagaggacctggtg gcaaatggggcccttgtcagcatctgtaacaagtatggagagatgcctgtggacaaagcc aaggcacccctgagagagcttctccgagagcgggcagagaagatgggccagaatctcaac cgtattccatacaaggacacattctggaaggggaccacccgcactcggccccgaaatgga accctgaacaaacactctggcattgacttcaaacagcttaacttcctgacgaagctcaac gagaatcactctggagagctatggaagggccgctggcagggcaatgacattgtcgtgaag gtgctgaaggttcgagactggagtacaaggaagagcagggacttcaatgaagagtgtccc cggctcaggattttctcgcatccaaatgtgctcccagtgctaggtgcctgccagtctcca cctgctcctcatcctactctcatcacacactggatgccgtatggatccctctacaatgta ctacatgaaggcaccaatttcgtcgtggaccagagccaggctgtgaagtttgctttggac atggcaaggggcatggccttcctacacacactagagcccctcatcccacgacatgcactc aatagccgtagtgtaatgattgatgaggacatgactgcccgaattagcatggctgatgtc aagttctctttccaatgtcctggtcgcatgtatgcacctgcctgggtagcccccgaagct ctgcagaagaagcctgaagacacaaacagacgctcagcagacatgtggagttttgcagtg cttctgtgggaactggtgacacgggaggtaccctttgctgacctctccaatatggagatt ggaatgaaggtggcattggaaggccttcggcctaccatcccaccaggtatttcccctcat gtgtgtaagctcatgaagatctgcatgaatgaagaccctgcaaagcgacccaaatttgac atgattgtgcctatccttgagaagatgcaggacaagtag |
Protein Sequence |
>3611 : length: 452 MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK |