Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3611

Name

ILK

Synonymous

HEL-S-28|ILK-1|ILK-2|P59|p59ILK;integrin-linked kinase;ILK;integrin-linked kinase

Definition

59 kDa serine/threonine-protein kinase|epididymis secretory protein Li 28|integrin-linked kinase-2|integrin-linked protein kinase

Position

11p15.4

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

ACTN1NCI_NATURE;

in same component

ARHGEF7NCI_NATURE;

in same component

ELMO2NCI_NATURE;

in same component

GIT2NCI_NATURE;

in same component

ITGB1IMID;

in same component

ITGB1REACTOME;

in same component

LIMS1NCI_NATURE;

in same component

LIMS2NCI_NATURE;

in same component

NCK2NCI_NATURE;

in same component

PARVANCI_NATURE;

in same component

PARVBNCI_NATURE;

in same component

PARVGNCI_NATURE;

in same component

PXNNCI_NATURE;

in same component

RICTORNCI_NATURE;

in same component

TNS1NCI_NATURE;

in same component

ZYXNCI_NATURE;

interacts with

ABCF1MINT;

interacts with

ABCF3MINT;

interacts with

ACIN1MINT;

interacts with

ACP6BIOGRID;

interacts with

ACTBMINT;

interacts with

ACTL6AMINT;

interacts with

ACTR1AMINT;

interacts with

ADNPMINT;

interacts with

AHNAKMINT;

interacts with

AKT1BIOGRID;

interacts with

AKT1HPRD;

interacts with

ANAPC1MINT;

interacts with

ANLNMINT;

interacts with

AP1B1MINT;

interacts with

AP3B1MINT;

interacts with

APBB1IPMINT;

interacts with

API5MINT;

interacts with

AQRMINT;

interacts with

ARAP1MINT;

interacts with

ARCN1MINT;

interacts with

ARF4MINT;

interacts with

ARFGEF2MINT;

interacts with

ARHGEF1MINT;

interacts with

ARHGEF2MINT;

interacts with

ARID1AMINT;

interacts with

ATMMINT;

interacts with

ATRMINT;

interacts with

ATRXMINT;

interacts with

AUP1BIOGRID;

interacts with

AURKAMINT;

interacts with

AURKBMINT;

interacts with

BABAM1MINT;

interacts with

BAZ1AMINT;

interacts with

BCAS2MINT;

interacts with

BCL7CMINT;

interacts with

BCLAF1MINT;

interacts with

BLMMINT;

interacts with

BRD8MINT;

interacts with

BRIX1MINT;

interacts with

BTAF1MINT;

interacts with

BUB1BMINT;

interacts with

BUB1MINT;

interacts with

BUB3MINT;

interacts with

BZW1MINT;

interacts with

BZW2MINT;

interacts with

C12orf11MINT;

interacts with

C22orf28MINT;

interacts with

CAND1MINT;

interacts with

CAPGMINT;

interacts with

CAPZA1MINT;

interacts with

CASP8HPRD;

interacts with

CASP9HPRD;

interacts with

CAV1HPRD;

interacts with

CCNB1MINT;

interacts with

CCNT1MINT;

interacts with

CCT2MINT;

interacts with

CCT3MINT;

interacts with

CCT4MINT;

interacts with

CCT5MINT;

interacts with

CCT6AMINT;

interacts with

CCT7MINT;

interacts with

CCT8MINT;

interacts with

CDC16MINT;

interacts with

CDC23MINT;

interacts with

CDC27MINT;

interacts with

CDC5LMINT;

interacts with

CDC73MINT;

interacts with

CDK12MINT;

interacts with

CDK1MINT;

interacts with

CDK3MINT;

interacts with

CDK9MINT;

interacts with

CDKN2AIPMINT;

interacts with

CHD1LMINT;

interacts with

CHD3MINT;

interacts with

CHD4MINT;

interacts with

CHD7MINT;

interacts with

CHD8MINT;

interacts with

CHEK1MINT;

interacts with

CHERPMINT;

interacts with

CKAP5MINT;

interacts with

CLP1MINT;

interacts with

CNOT1MINT;

interacts with

COBRA1MINT;

interacts with

COPAMINT;

interacts with

COPB1MINT;

interacts with

COPB2BIOGRID;

interacts with

COPB2MINT;

interacts with

COPG2MINT;

interacts with

COPGBIOGRID;

interacts with

COPGMINT;

interacts with

COPS3MINT;

interacts with

COPS5MINT;

interacts with

COPS6MINT;

interacts with

CPNE3MINT;

interacts with

CPSF1MINT;

interacts with

CPSF2MINT;

interacts with

CPSF3MINT;

interacts with

CPSF4MINT;

interacts with

CPSF7MINT;

interacts with

CSDAMINT;

interacts with

CSE1LMINT;

interacts with

CSKMINT;

interacts with

CSTF3MINT;

interacts with

CTTNMINT;

interacts with

CUL1MINT;

interacts with

DCTN1MINT;

interacts with

DCTN2MINT;

interacts with

DDX17MINT;

interacts with

DDX19AMINT;

interacts with

DDX19BMINT;

interacts with

DDX1MINT;

interacts with

DDX21MINT;

interacts with

DDX23MINT;

interacts with

DDX39AMINT;

interacts with

DDX39BMINT;

interacts with

DDX3XBIOGRID;

interacts with

DDX3XMINT;

interacts with

DDX41MINT;

interacts with

DDX42MINT;

interacts with

DDX46MINT;

interacts with

DEPDC7MINT;

interacts with

DFNA5MINT;

interacts with

DHX36BIOGRID;

interacts with

DHX8MINT;

interacts with

DHX9MINT;

interacts with

DIAPH1MINT;

interacts with

DIAPH3MINT;

interacts with

DIDO1MINT;

interacts with

DMAP1MINT;

interacts with

DNAJA1MINT;

interacts with

DNAJC13MINT;

interacts with

DNM1LMINT;

interacts with

DNM2MINT;

interacts with

DOCK1MINT;

interacts with

DOCK2MINT;

interacts with

DPF2MINT;

interacts with

DRG1MINT;

interacts with

DSPMINT;

interacts with

DYNC1H1MINT;

interacts with

DYNC1LI2MINT;

interacts with

EBNA1BP2MINT;

interacts with

EEF1A1MINT;

interacts with

EEFSECMINT;

interacts with

EFTUD2MINT;

interacts with

EHD1MINT;

interacts with

EHD4MINT;

interacts with

EIF2S1MINT;

interacts with

EIF2S2MINT;

interacts with

EIF2S3MINT;

interacts with

EIF3EMINT;

interacts with

EIF3GMINT;

interacts with

EIF3HMINT;

interacts with

EIF3IMINT;

interacts with

EIF3LMINT;

interacts with

EIF4A1MINT;

interacts with

EIF4A3MINT;

interacts with

EIF4G2MINT;

interacts with

EIF5BMINT;

interacts with

ELAVL1MINT;

interacts with

ENAHMINT;

interacts with

EPPK1MINT;

interacts with

EPS8L2MINT;

interacts with

ERHBIOGRID;

interacts with

ETF1MINT;

interacts with

ETV6MINT;

interacts with

EWSR1BIOGRID;

interacts with

EXOC1MINT;

interacts with

EXOC2MINT;

interacts with

EXOC3MINT;

interacts with

EXOC4MINT;

interacts with

EXOC5MINT;

interacts with

EXOC7MINT;

interacts with

EXOSC10MINT;

interacts with

EXOSC6MINT;

interacts with

FAM105BMINT;

interacts with

FAM129BMINT;

interacts with

FANCIBIOGRID;

interacts with

FANCIMINT;

interacts with

FASNMINT;

interacts with

FEN1MINT;

interacts with

FERMT1MINT;

interacts with

FHOD1MINT;

interacts with

FIP1L1MINT;

interacts with

FUBP1MINT;

interacts with

FYTTD1MINT;

interacts with

G3BP2MINT;

interacts with

GATAD2AMINT;

interacts with

GATAD2BMINT;

interacts with

GCN1L1MINT;

interacts with

GEMIN4BIOGRID;

interacts with

GEMIN4MINT;

interacts with

GNA14MINT;

interacts with

GSK3BHPRD;

interacts with

GSPT1MINT;

interacts with

GTF2IMINT;

interacts with

GTF3C1MINT;

interacts with

GTF3C2MINT;

interacts with

GTF3C3MINT;

interacts with

GTF3C4MINT;

interacts with

GTPBP4MINT;

interacts with

GULP1MINT;

interacts with

HBS1LMINT;

interacts with

HDAC1MINT;

interacts with

HDAC2MINT;

interacts with

HDLBPMINT;

interacts with

HEATR1BIOGRID;

interacts with

HEATR2BIOGRID;

interacts with

HELLSMINT;

interacts with

HIP1RMINT;

interacts with

HIRAMINT;

interacts with

HLTFMINT;

interacts with

HNRNPA0MINT;

interacts with

HNRNPA1MINT;

interacts with

HNRNPA2B1MINT;

interacts with

HNRNPA3MINT;

interacts with

HNRNPABMINT;

interacts with

HNRNPCMINT;

interacts with

HNRNPDMINT;

interacts with

HNRNPFMINT;

interacts with

HNRNPH1MINT;

interacts with

HNRNPMMINT;

interacts with

HNRNPRMINT;

interacts with

HNRNPUMINT;

interacts with

HSP90AA1MINT;

interacts with

HSP90AB1MINT;

interacts with

HSP90B1MINT;

interacts with

HSPA12AMINT;

interacts with

HSPA5MINT;

interacts with

HSPA8MINT;

interacts with

HSPB1BIOGRID;

interacts with

HSPB1MINT;

interacts with

HSPD1MINT;

interacts with

HTATSF1MINT;

interacts with

IGF2BP1BIOGRID;

interacts with

IKMINT;

interacts with

ILF2MINT;

interacts with

ILF3MINT;

interacts with

ILKAPBIOGRID;

interacts with

ILKAPHPRD;

interacts with

INTS12MINT;

interacts with

INTS1MINT;

interacts with

INTS3MINT;

interacts with

IPO5MINT;

interacts with

IPO9MINT;

interacts with

IQGAP1MINT;

interacts with

ITGA5BIOGRID;

interacts with

ITGB1BIOGRID;

interacts with

ITGB1HPRD;

interacts with

ITGB2HPRD;

interacts with

ITGB3BIOGRID;

interacts with

ITGB3HPRD;

interacts with

KDM1AMINT;

interacts with

KHDRBS1MINT;

interacts with

KIAA1279MINT;

interacts with

KIF11MINT;

interacts with

KIF21AMINT;

interacts with

KIF27MINT;

interacts with

KIF2CMINT;

interacts with

KIF4AMINT;

interacts with

KPNA1MINT;

interacts with

KPNA2MINT;

interacts with

KPNB1MINT;

interacts with

KTI12MINT;

interacts with

LDLRAP1MINT;

interacts with

LIMS1BIOGRID;

interacts with

LIMS1HPRD;

interacts with

LIMS1MINT;

interacts with

LIMS2BIOGRID;

interacts with

LIMS2HPRD;

interacts with

LMNAMINT;

interacts with

LRRC40MINT;

interacts with

LRRC47MINT;

interacts with

LRWD1MINT;

interacts with

LUC7L2MINT;

interacts with

MAD1L1MINT;

interacts with

MAGED2MINT;

interacts with

MAP2K2MINT;

interacts with

MAP2K3MINT;

interacts with

MAP2K7MINT;

interacts with

MARSBIOGRID;

interacts with

MATR3MINT;

interacts with

MBD3MINT;

interacts with

MDN1MINT;

interacts with

MED4MINT;

interacts with

METTL13MINT;

interacts with

MLH1MINT;

interacts with

MLKLMINT;

interacts with

MLL2MINT;

interacts with

MMS19BIOGRID;

interacts with

MORF4L1MINT;

interacts with

MORF4L2MINT;

interacts with

MRE11AMINT;

interacts with

MSH2MINT;

interacts with

MSH6MINT;

interacts with

MTA2MINT;

interacts with

MVPMINT;

interacts with

MYH9MINT;

interacts with

MYO15BMINT;

interacts with

MYO1DBIOGRID;

interacts with

NACC1MINT;

interacts with

NBNMINT;

interacts with

NCAPD2MINT;

interacts with

NCAPGMINT;

interacts with

NCAPHMINT;

interacts with

NCK2BIOGRID;

interacts with

NCK2HPRD;

interacts with

NCLMINT;

interacts with

NCOR1MINT;

interacts with

NCOR2MINT;

interacts with

NDC80MINT;

interacts with

NFICMINT;

interacts with

NIPBLMINT;

interacts with

NOC2LBIOGRID;

interacts with

NOLC1MINT;

interacts with

NONOMINT;

interacts with

NR2C2MINT;

interacts with

NR2F2MINT;

interacts with

NR2F6MINT;

interacts with

NSFMINT;

interacts with

NSUN5MINT;

interacts with

NUDCMINT;

interacts with

NUF2MINT;

interacts with

NUP153MINT;

interacts with

NUP155MINT;

interacts with

NUP37MINT;

interacts with

OLA1MINT;

interacts with

ORC2MINT;

interacts with

ORC3MINT;

interacts with

OTUD4BIOGRID;

interacts with

OXSR1MINT;

interacts with

PABPC1MINT;

interacts with

PABPN1MINT;

interacts with

PAK1MINT;

interacts with

PAK4MINT;

interacts with

PARP4MINT;

interacts with

PARVABIOGRID;

interacts with

PARVAHPRD;

interacts with

PARVAMINT;

interacts with

PARVBBIOGRID;

interacts with

PARVBHPRD;

interacts with

PARVBMINT;

interacts with

PARVGHPRD;

interacts with

PAXIP1MINT;

interacts with

PBRM1MINT;

interacts with

PCBP2MINT;

interacts with

PCF11MINT;

interacts with

PDCD6IPMINT;

interacts with

PDLIM7MINT;

interacts with

PDPK1BIOGRID;

interacts with

PDPK1HPRD;

interacts with

PELP1MINT;

interacts with

PFKMMINT;

interacts with

PFKPMINT;

interacts with

PHGDHMINT;

interacts with

PICALMMINT;

interacts with

PIK3R4MINT;

interacts with

PKN2MINT;

interacts with

PKP3MINT;

interacts with

PLECMINT;

interacts with

PLK1MINT;

interacts with

PLRG1MINT;

interacts with

PNNMINT;

interacts with

POGZMINT;

interacts with

POLD1MINT;

interacts with

POLEMINT;

interacts with

POLR1CMINT;

interacts with

POLR2AMINT;

interacts with

POLR2EMINT;

interacts with

PPP1CAMINT;

interacts with

PPP1R12AHPRD;

interacts with

PPP2R1AMINT;

interacts with

PPP2R1BMINT;

interacts with

PRKAG1MINT;

interacts with

PRKDCMINT;

interacts with

PRPF19MINT;

interacts with

PRPF40AMINT;

interacts with

PRPF6MINT;

interacts with

PRPF8MINT;

interacts with

PRPSAP1BIOGRID;

interacts with

PSMC1MINT;

interacts with

PSMC2MINT;

interacts with

PSMC3MINT;

interacts with

PSMC4MINT;

interacts with

PSMC5MINT;

interacts with

PSMC6MINT;

interacts with

PSMD11MINT;

interacts with

PSMD12MINT;

interacts with

PSMD13MINT;

interacts with

PSMD1MINT;

interacts with

PSMD2MINT;

interacts with

PSMD3MINT;

interacts with

PTBP1MINT;

interacts with

PUF60BIOGRID;

interacts with

PUF60MINT;

interacts with

PUM2MINT;

interacts with

PURAMINT;

interacts with

PWP1MINT;

interacts with

PXNBIOGRID;

interacts with

PXNHPRD;

interacts with

RACGAP1MINT;

interacts with

RAD18MINT;

interacts with

RAD21MINT;

interacts with

RAD50MINT;

interacts with

RAE1MINT;

interacts with

RALYMINT;

interacts with

RANBP2MINT;

interacts with

RANGAP1MINT;

interacts with

RBBP5MINT;

interacts with

RBBP7MINT;

interacts with

RBM10MINT;

interacts with

RBM14MINT;

interacts with

RBM15MINT;

interacts with

RBM17MINT;

interacts with

RBM39MINT;

interacts with

RBM45MINT;

interacts with

RBM4MINT;

interacts with

RBMXMINT;

interacts with

RCOR1MINT;

interacts with

RFC2MINT;

interacts with

RFC3MINT;

interacts with

RFC4MINT;

interacts with

RFC5MINT;

interacts with

RIF1MINT;

interacts with

RING1MINT;

interacts with

RIOK1MINT;

interacts with

RNF2MINT;

interacts with

ROCK2MINT;

interacts with

RPL12MINT;

interacts with

RPL13MINT;

interacts with

RPL22MINT;

interacts with

RPL36MINT;

interacts with

RPL3MINT;

interacts with

RPL4MINT;

interacts with

RPLP0MINT;

interacts with

RPS19MINT;

interacts with

RPS3MINT;

interacts with

RPS6KA4MINT;

interacts with

RPS6KB2MINT;

interacts with

RSU1BIOGRID;

interacts with

RUVBL1MINT;

interacts with

RUVBL2MINT;

interacts with

S100A9BIOGRID;

interacts with

SART1MINT;

interacts with

SCYL2MINT;

interacts with

SEC23BMINT;

interacts with

SEC31BMINT;

interacts with

SEH1LMINT;

interacts with

SEPT7MINT;

interacts with

SEPT9MINT;

interacts with

SETXMINT;

interacts with

SF3A1MINT;

interacts with

SF3A3MINT;

interacts with

SF3B14MINT;

interacts with

SF3B1MINT;

interacts with

SF3B2MINT;

interacts with

SF3B3MINT;

interacts with

SF3B4MINT;

interacts with

SFPQMINT;

interacts with

SHOC2MINT;

interacts with

SHROOM3MINT;

interacts with

SMARCA2MINT;

interacts with

SMARCA5MINT;

interacts with

SMARCAD1MINT;

interacts with

SMARCB1MINT;

interacts with

SMARCC1MINT;

interacts with

SMARCC2MINT;

interacts with

SMARCD1MINT;

interacts with

SMARCE1MINT;

interacts with

SMC1AMINT;

interacts with

SMC2MINT;

interacts with

SMC3MINT;

interacts with

SMC4MINT;

interacts with

SMCHD1MINT;

interacts with

SMN1MINT;

interacts with

SND1MINT;

interacts with

SNRNP200MINT;

interacts with

SNRNP40MINT;

interacts with

SNRNP70MINT;

interacts with

SNRPB2MINT;

interacts with

SNUPNMINT;

interacts with

SNW1MINT;

interacts with

SPATA5MINT;

interacts with

SPATA5L1MINT;

interacts with

SPTAN1MINT;

interacts with

SPTBN1MINT;

interacts with

SQSTM1MINT;

interacts with

SRP19MINT;

interacts with

SRP54MINT;

interacts with

SRP68MINT;

interacts with

SRP72MINT;

interacts with

SRRM1MINT;

interacts with

SRRM2MINT;

interacts with

SRSF11MINT;

interacts with

SRSF1MINT;

interacts with

SRSF2MINT;

interacts with

SRSF5MINT;

interacts with

SRSF6MINT;

interacts with

SRSF7MINT;

interacts with

STAG1MINT;

interacts with

SUGT1MINT;

interacts with

SUPV3L1MINT;

interacts with

SYMPKMINT;

interacts with

SYNCRIPMINT;

interacts with

TAF12MINT;

interacts with

TAF9MINT;

interacts with

TAOK1MINT;

interacts with

TARDBPMINT;

interacts with

TBL1XR1MINT;

interacts with

TCP1MINT;

interacts with

TH1LMINT;

interacts with

THOC1MINT;

interacts with

THOC2MINT;

interacts with

THRAP3MINT;

interacts with

TIAL1MINT;

interacts with

TLN1MINT;

interacts with

TMPOMINT;

interacts with

TOX4MINT;

interacts with

TRAP1MINT;

interacts with

TRIM28MINT;

interacts with

TRIP12MINT;

interacts with

TRIP13MINT;

interacts with

TRUB1MINT;

interacts with

TSG101MINT;

interacts with

TTKMINT;

interacts with

TUBA3EMINT;

interacts with

TUBA4AMINT;

interacts with

TUBB1MINT;

interacts with

TUBB2CMINT;

interacts with

TUBB3MINT;

interacts with

TUBBMINT;

interacts with

TUBG1MINT;

interacts with

TUBGCP2MINT;

interacts with

TUBGCP3MINT;

interacts with

TUFMMINT;

interacts with

TWF1MINT;

interacts with

U2AF1MINT;

interacts with

U2AF2MINT;

interacts with

U2SURPMINT;

interacts with

UBA5MINT;

interacts with

UBE2MMINT;

interacts with

UBE2NMINT;

interacts with

UBE2Q1MINT;

interacts with

UBL4AMINT;

interacts with

UCHL5MINT;

interacts with

UNC45AMINT;

interacts with

UPF1MINT;

interacts with

UPF2MINT;

interacts with

USP39MINT;

interacts with

USP48MINT;

interacts with

VASPMINT;

interacts with

VIMMINT;

interacts with

VPS33BMINT;

interacts with

VRK1MINT;

interacts with

WAPALMINT;

interacts with

WDR18MINT;

interacts with

WDR33MINT;

interacts with

WDR5MINT;

interacts with

WIZMINT;

interacts with

XPO6MINT;

interacts with

XRCC6MINT;

interacts with

XRN2MINT;

interacts with

YTHDC2MINT;

interacts with

YY1MINT;

interacts with

ZNF326MINT;

interacts with

ZNF638MINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

ITGAVNCI_NATURE;

metabolic catalysis

ITGB3NCI_NATURE;

metabolic catalysis

SPP1NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

ACTN1NCI_NATURE;

reacts with

ARHGEF7NCI_NATURE;

reacts with

CDC37NCI_NATURE;

reacts with

ELMO2NCI_NATURE;

reacts with

GIT2NCI_NATURE;

reacts with

HSP90AA1NCI_NATURE;

reacts with

ILKIMID;

reacts with

ILKNCI_NATURE;

reacts with

ILKREACTOME;

reacts with

ITGB1IMID;

reacts with

ITGB1REACTOME;

reacts with

LIMS1NCI_NATURE;

reacts with

LIMS2NCI_NATURE;

reacts with

NCK2NCI_NATURE;

reacts with

PARVANCI_NATURE;

reacts with

PARVBNCI_NATURE;

reacts with

PARVGNCI_NATURE;

reacts with

PXNNCI_NATURE;

reacts with

RICTORNCI_NATURE;

reacts with

TNS1NCI_NATURE;

reacts with

ZYXNCI_NATURE;

state change

ILKAPNCI_NATURE;

state change

ITGAVNCI_NATURE;

state change

ITGB3NCI_NATURE;

state change

RUVBL1NCI_NATURE;

state change

RUVBL2NCI_NATURE;

state change

VTNNCI_NATURE;

state change

XPO1NCI_NATURE;


')