| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3611 |
Name | ILK |
Synonymous | HEL-S-28|ILK-1|ILK-2|P59|p59ILK;integrin-linked kinase;ILK;integrin-linked kinase |
Definition | 59 kDa serine/threonine-protein kinase|epididymis secretory protein Li 28|integrin-linked kinase-2|integrin-linked protein kinase |
Position | 11p15.4 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
PINCH-1(h) + ILK(h) <==> PINCH-1(h):ILK(h) (binding) | Nck-2(h) + ILK(h) + PINCH-1(h) <==> Nck-2(h):PINCH-1(h):ILK(h) (binding) | ILK(h) + beta-parvin(h) <==> ILK(h):beta-parvin(h) (binding) | ILK(h) + actopaxin(h) <==> ILK(h):actopaxin(h) (binding) | ILK(h) + ILKAP(h) <==> ILK(h):ILKAP(h) (binding) | ILK(h) --> ILK(h) (translocation) | ILK(h) --/ CNKSR3(h) (transrepression) | PACPL1(h) + ILK(h) <==> PACPL1(h):ILK(h) (binding) | ILK(h) + BAP28(h) <==> ILK(h):BAP28(h) (binding) | ILK(h) + HIN1(h) <==> ILK(h):HIN1(h) (binding) | ILK(h) + FANCI(h) <==> ILK(h):FANCI(h) (binding) | ILK(h) + Gemin-4(h) <==> ILK(h):Gemin-4(h) (binding) | ILK(h) + DDX3(h) <==> ILK(h):DDX3(h) (binding) | ILK(h) + MMS19L(h) <==> ILK(h):MMS19L(h) (binding) | ILK(h) + myr4(h) <==> ILK(h):myr4(h) (binding) | ILK(h) + heatr2(h) <==> ILK(h):heatr2(h) (binding) | ILK(h) + Rsu-1(h) <==> ILK(h):Rsu-1(h) (binding) | ILK(h) + aup-1(h) <==> ILK(h):aup-1(h) (binding) | ILK(h) + NIR(h) <==> ILK(h):NIR(h) (binding) | ILK(h) + IMP-1(h) <==> ILK(h):IMP-1(h) (binding) | ILK(h) + COPG1(h) <==> ILK(h):COPG1(h) (binding) | ILK(h) + MRP-14(h) <==> ILK(h):MRP-14(h) (binding) | ILK(h) + EWS(h) <==> ILK(h):EWS(h) (binding) | ILK(h) + SIAHBP1(h) <==> ILK(h):SIAHBP1(h) (binding) | ILK(h) + METRS(h) <==> ILK(h):METRS(h) (binding) | ILK(h) + PAP39(h) <==> ILK(h):PAP39(h) (binding) | ILK(h) + DDX36(h) <==> ILK(h):DDX36(h) (binding) | ILK(h) + COPB2(h) <==> ILK(h):COPB2(h) (binding) | ILK(h) + ERH(h) <==> ILK(h):ERH(h) (binding) | ILK(h) + Hsp27(h) <==> ILK(h):Hsp27(h) (binding) | ILK(h) --> ILK(h) (expression). | ILK(h) --> ILK(h) (translocation) | GSK3(v.s.) + NTP --ILK(h)--> GSK3(v.s.){p} + NDP (phosphorylation) | AKT(h) + ATP --ILK(h)--> AKT(h){pS473} + ADP (phosphorylation) | ILK(h) --> ILK(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
343 | Phosphoserine (ILK) | 11313365 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 6580283 - 6582283 | Agilent_014791 |
chr11 |
Promoter: 6580283 - 6582283 | GSE27584 |
chr11 |
Promoter: 6580040 - 6582040 | GSE27584 |
chr11 |
Promoter: 6580040 - 6582040 | GSE27584 |
chr11 |
Promoter: 6580040 - 6582040 | Agilent_014791_44K |