| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4303 |
Name | FOXO4 |
Synonym | AFX|AFX1|MLLT7;forkhead box O4;FOXO4;forkhead box O4 |
Definition | fork head domain transcription factor AFX1|forkhead box protein O4|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7 |
Position | Xq13.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 7352 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
|
Pathways and Diseases |
|
Pathway | Class I PI3K signaling events mediated by Akt;PID Curated;200169 |
Pathway | Signaling events mediated by HDAC Class III;PID Curated;200020 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | ras signaling pathway;PID BioCarta;100047 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | akt signaling pathway;PID BioCarta;100245 |
|
External Links |
|
Links to Entrez Gene | 4303 |
Links to all GeneRIF Items | 4303 |
Links to iHOP | 4303 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>4303 : length: 1353 atggatccggggaatgagaattcagccacagaggctgccgcgatcatagacctagatccc gacttcgaaccccagagccgtccccgctcctgcacctggccccttccccgaccagagatc gctaaccagccgtccgagccgcccgaggtggagccagatctgggggaaaaggccattgaa agcgccccggagaagcgactgacacttgcccagatctacgagtggatggtccgtactgta ccctacttcaaggacaagggtgacagcaacagctcagcaggatggaagaactcgatccgc cacaacctgtccctgcacagcaagttcatcaaggttcacaacgaggccaccggcaaaagc tcttggtggatgctgaaccctgagggaggcaagagcggcaaagccccccgccgccgggcc gcctccatggatagcagcagcaagctgctccggggccgcagtaaagcccccaagaagaaa ccatctgtgctgccagctccacccgaaggtgccactccaacgagccctgtcggccacttt gccaagtggtcaggcagcccttgctctcgaaaccgtgaagaagccgatatgtggaccacc ttccgtccacgaagcagttcaaatgccagcagtgtcagcacccggctgtcccccttgagg ccagagtctgaggtgctggcggaggaaataccagcttcagtcagcagttatgcagggggt gtccctcccaccctcaatgaaggtctagagctgttagatgggctcaatctcacctcttcc cattccctgctatctcggagtggtctctctggcttctctttgcagcatcctggggttacc ggccccttacacacctacagcagctcccttttcagcccagcagaggggcccctgtcagca ggagaagggtgcttctccagctcccaggctctggaggccctgctcacctctgatacgcca ccaccccctgctgacgtcctcatgacccaggtagatcccattctgtcccaggctccgact cttctgttgctgggggggcttccttcctccagtaagctggccacgggcgtcggcctgtgt cccaagcccctagaggctccaggccccagcagtctggttcccaccctttctatgatagca ccacctccagtcatggcaagtgcccccatccccaaggctctggggactcctgtgctcaca ccccctactgaagctgcaagccaagacagaatgcctcaggatctagatcttgatatgtat atggagaacctggagtgtgacatggataacatcatcagtgacctcatggatgagggcgag ggactggacttcaactttgagccagatccctga |
Protein Sequence |
>4303 : length: 450 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKAIE SAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKS SWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHF AKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGG VPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSA GEGCFSSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLC PKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMY MENLECDMDNIISDLMDEGEGLDFNFEPDP |