| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 4916 |
Name | NTRK3 |
Synonym | GP145-TrkC|TRKC|gp145(trkC);neurotrophic tyrosine kinase, receptor, type 3;NTRK3;neurotrophic tyrosine kinase, receptor, type 3 |
Definition | ETS related protein-neurotrophic receptor tyrosine kinase fusion protein|ETV6-NTRK3 fusion|NT-3 growth factor receptor|tyrosine kinase receptor C |
Position | 15q25 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 11635 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Disease | Cancers of the nervous system;KEGG DISEASE |
Disease | Neuroblastoma;KEGG DISEASE;H00043 |
Disease | Cancers;KEGG DISEASE |
Disease | PSYCH;GAD |
Disease | panic disorder;GAD |
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External Links |
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Links to Entrez Gene | 4916 |
Links to all GeneRIF Items | 4916 |
Links to iHOP | 4916 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>4916 : length: 1839 atggatgtctctctttgcccagccaagtgtagtttctggcggattttcttgctgggaagc gtctggctggactatgtgggctccgtgctggcttgccctgcaaattgtgtctgcagcaag actgagatcaattgccggcggccggacgatgggaacctcttccccctcctggaagggcag gattcagggaacagcaatgggaacgccagtatcaacatcacggacatctcaaggaatatc acttccatacacatagagaactggcgcagtcttcacacgctcaacgccgtggacatggag ctctacaccggacttcaaaagctgaccatcaagaactcaggacttcggagcattcagccc agagcctttgccaagaacccccatttgcgttatataaacctgtcaagtaaccggctcacc acactctcgtggcagctcttccagacgctgagtcttcgggaattgcagttggagcagaac tttttcaactgcagctgtgacatccgctggatgcagctctggcaggagcagggggaggcc aagctcaacagccagaacctctactgcatcaacgctgatggctcccagcttcctctcttc cgcatgaacatcagtcagtgtgaccttcctgagatcagcgtgagccacgtcaacctgacc gtacgagagggtgacaatgctgttatcacttgcaatggctctggatcaccccttcctgat gtggactggatagtcactgggctgcagtccatcaacactcaccagaccaatctgaactgg accaatgttcatgccatcaacttgacgctggtgaatgtgacgagtgaggacaatggcttc accctgacgtgcattgcagagaacgtggtgggcatgagcaatgccagtgttgccctcact gtctactatcccccacgtgtggtgagcctggaggagcctgagctgcgcctggagcactgc atcgagtttgtggtgcgtggcaaccccccaccaacgctgcactggctgcacaatgggcag cctctgcgggagtccaagatcatccatgtggaatactaccaagagggagagatttccgag ggctgcctgctcttcaacaagcccacccactacaacaatggcaactataccctcattgcc aaaaacccactgggcacagccaaccagaccatcaatggccacttcctcaaggagcccttt ccagagagcacggataactttatcttgtttgacgaagtgagtcccacacctcctatcact gtgacccacaaaccagaagaagacacttttggggtatccatagcagttggacttgctgct tttgcctgtgtcctgttggtggttctcttcgtcatgatcaacaaatatggtcgacggtcc aaatttggaatgaagggtcccgtggctgtcatcagtggtgaggaggactcagccagccca ctgcaccacatcaaccacggcatcaccacgccctcgtcactggatgccgggcccgacact gtggtcattggcatgactcgcatccctgtcattgagaacccccagtacttccgtcaggga cacaactgccacaagccggacacgtgggtcttttcaaacatagacaatcatgggatatta aacttgaaggacaatagagatcatctagtcccatcaactcactatatatatgaggaacct gaggtccagagtggggaagtgtcttacccaaggtcacatggtttcagagaaattatgttg aatccaataagccttcccggacattccaagcctcttaaccatggcatctatgttgaggat gtcaatgtttatttcagcaaaggacgtcatggcttttaa |
Protein Sequence |
>4916 : length: 612 MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQ DSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQP RAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEA KLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPD VDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALT VYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISE GCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPIT VTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASP LHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTWVFSNIDNHGIL NLKDNRDHLVPSTHYIYEEPEVQSGEVSYPRSHGFREIMLNPISLPGHSKPLNHGIYVED VNVYFSKGRHGF |