| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4916 |
Name | NTRK3 |
Synonymous | GP145-TrkC|TRKC|gp145(trkC);neurotrophic tyrosine kinase, receptor, type 3;NTRK3;neurotrophic tyrosine kinase, receptor, type 3 |
Definition | ETS related protein-neurotrophic receptor tyrosine kinase fusion protein|ETV6-NTRK3 fusion|NT-3 growth factor receptor|tyrosine kinase receptor C |
Position | 15q25 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
trkC(h) + DOK5(m.s.) <==> trkC(h):DOK5(m.s.) (binding) | trkC(h) + ATP --> trkC(h){pY} + ADP (phosphorylation; automodification) | Tamalin(m) + trkC(h) <==> Tamalin(m):trkC(h) (binding) | Tamalin(m) + trkC(h) <==> Tamalin(m):trkC(h) (binding) | trkC(h) + Src(h) <==> trkC(h):Src(h) (binding) | NTRK3(h) --> trkC(h) (expression). | NTRK3(h) --> trkC(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
72 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 79 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 133 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 163 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 203 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 218 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 232 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 259 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 267 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 272 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 294 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 375 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 388 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 516 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 705 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 709 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 710 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 834 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 | 516 | Phosphotyrosine | 11877382 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr15 |
Promoter: 86600165 - 86602165 | Agilent_014791 |
chr15 |
Promoter: 86600165 - 86602165 | GoldenGate_Methylation_Cancer_Panel_I |
chr15 |
Promoter: 86600165 - 86602165 | GoldenGate_Methylation_Cancer_Panel_I |
chr15 |
Promoter: 86600165 - 86602165 | GoldenGate_Methylation_Cancer_Panel_I |
chr15 |
Promoter: 86600165 - 86602165 | GSE27584 |
chr15 |
Promoter: 86600165 - 86602165 | GSE27584 |
chr15 |
Promoter: 86600165 - 86602165 | GSE27584 |
chr15 |
Promoter: 86600165 - 86602165 | Agilent_014791_44K |
chr15 |
Promoter: 86600165 - 86602165 | Agilent_014791_44K |
chr15 |
Promoter: 86600165 - 86602165 | Agilent_014791_44K |