| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5494 |
Name | PPM1A |
Synonym | PP2C-ALPHA|PP2CA|PP2Calpha;protein phosphatase, Mg2+/Mn2+ dependent, 1A;PPM1A;protein phosphatase, Mg2+/Mn2+ dependent, 1A |
Definition | protein phosphatase 1A|protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform |
Position | 14q23.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 13182 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Regulation of cytoplasmic and nuclear SMAD2/3 signaling;PID Curated;200152 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | BMP receptor signaling;PID Curated;200123 |
Pathway | Regulation of AMPK activity via LKB1;PID Reactome;500502 |
|
External Links |
|
Links to Entrez Gene | 5494 |
Links to all GeneRIF Items | 5494 |
Links to iHOP | 5494 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5494 : length: 1149 atgggagcatttttagacaagccaaagatggaaaagcataatgcccaggggcagggtaat gggttgcgatatgggctaagcagcatgcaaggctggcgtgttgaaatggaggatgcacat acggctgtgatcggtttgccaagtggacttgaatcgtggtcattctttgctgtgtatgat gggcatgctggttctcaggttgccaaatactgctgtgagcatttgttagatcacatcacc aataaccaggattttaaagggtctgcaggagcaccttctgtggaaaatgtaaagaatgga atcagaacaggttttctggagattgatgaacacatgagagttatgtcagagaagaaacat ggtgcagatagaagtgggtcaacagctgtaggtgtcttaatttctccccaacatacttat ttcattaactgtggagactcaagaggtttactttgtaggaacaggaaagttcatttcttc acacaagatcacaaaccaagtaatccgctggagaaagaacgaattcagaatgcaggtggc tctgtaatgattcagcgtgtgaatggctctctggctgtatcgagggcccttggggatttt gattacaaatgtgtccatggaaaaggtcctactgagcagcttgtctcaccagagcctgaa gtccatgatattgaaagatctgaagaagatgatcagttcattatccttgcatgtgatggt atctgggatgttatgggaaatgaagagctctgtgattttgtaagatccagacttgaagtc actgatgaccttgagaaagtttgcaatgaagtagtcgacacctgtttgtataagggaagt cgagacaacatgagtgtgattttgatctgttttccaaatgcacccaaagtatcgccagaa gcagtgaagaaggaggcagagttggacaagtacctggaatgcagagtagaagaaatcata aagaagcagggggaaggcgtccccgacttagtccatgtgatgcgcacattagcgagtgag aacatccccagcctcccaccagggggtgaattggcaagcaagaggaatgttattgaagcc gtttacaatagactgaatccttacaaaaatgacgacactgactctacatcaacagatgat atgtggtaa |
Protein Sequence |
>5494 : length: 382 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE AVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEA VYNRLNPYKNDDTDSTSTDDMW |