| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 55294 |
Name | FBXW7 |
Synonym | AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase;FBXW7;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
Definition | F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)|F-box protein FBW7|F-box protein FBX30|F-box protein SEL-10|F-box/WD repeat-containing protein 7|archipelago|homolog of C elegans sel-10 |
Position | 4q31.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 19 |
TUSON P-value | 6.03E-29 |
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Pathways and Diseases |
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Pathway | Notch signaling pathway;PANTHER;P00045 |
Pathway | Metabolism of proteins;Reactome;REACT:17015 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | C-MYC pathway;PID Curated;200093 |
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External Links |
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Links to Entrez Gene | 55294 |
Links to all GeneRIF Items | 55294 |
Links to iHOP | 55294 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>55294 : length: 1770 atgtcaaaaccgggaaaacctactctaaaccatggcttggttcctgttgatcttaaaagt gcaaaagagcctctaccacatcaaactgtgatgaagatatttagcattagcatcattgcc caaggcctccctttttgtcgaagacggatgaaaagaaagttggaccatggttctgaggtc cgctctttttctttgggaaagaaaccatgcaaagtctcagaatatacaagtaccactggg cttgtaccatgttcagcaacaccaacaacttttggggacctcagagcagccaatggccaa gggcaacaacgacgccgaattacatctgtccagccacctacaggcctccaggaatggcta aaaatgtttcagagctggagtggaccagagaaattgcttgctttagatgaactcattgat agttgtgaaccaacacaagtaaaacatatgatgcaagtgatagaaccccagtttcaacga gacttcatttcattgctccctaaagagttggcactctatgtgctttcattcctggaaccc aaagacctgctacaagcagctcagacatgtcgctactggagaattttggctgaagacaac cttctctggagagagaaatgcaaagaagaggggattgatgaaccattgcacatcaagaga agaaaagtaataaaaccaggtttcatacacagtccatggaaaagtgcatacatcagacag cacagaattgatactaactggaggcgaggagaactcaaatctcctaaggtgctgaaagga catgatgatcatgtgatcacatgcttacagttttgtggtaaccgaatagttagtggttct gatgacaacactttaaaagtttggtcagcagtcacaggcaaatgtctgagaacattagtg ggacatacaggtggagtatggtcatcacaaatgagagacaacatcatcattagtggatct acagatcggacactcaaagtgtggaatgcagagactggagaatgtatacacaccttatat gggcatacttccactgtgcgttgtatgcatcttcatgaaaaaagagttgttagcggttct cgagatgccactcttagggtttgggatattgagacaggccagtgtttacatgttttgatg ggtcatgttgcagcagtccgctgtgttcaatatgatggcaggagggttgttagtggagca tatgattttatggtaaaggtgtgggatccagagactgaaacctgtctacacacgttgcag gggcatactaatagagtctattcattacagtttgatggtatccatgtggtgagtggatct cttgatacatcaatccgtgtttgggatgtggagacagggaattgcattcacacgttaaca gggcaccagtcgttaacaagtggaatggaactcaaagacaatattcttgtctctgggaat gcagattctacagttaaaatctgggatatcaaaacaggacagtgtttacaaacattgcaa ggtcccaacaagcatcagagtgctgtgacctgtttacagttcaacaagaactttgtaatt accagctcagatgatggaactgtaaaactatgggacttgaaaacgggtgaatttattcga aacctagtcacattggagagtggggggagtgggggagttgtgtggcggatcagagcctca aacacaaagctggtgtgtgcagttgggagtcggaatgggactgaagaaaccaagctgctg gtgctggactttgatgtggacatgaagtga |
Protein Sequence |
>55294 : length: 589 MSKPGKPTLNHGLVPVDLKSAKEPLPHQTVMKIFSISIIAQGLPFCRRRMKRKLDHGSEV RSFSLGKKPCKVSEYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWL KMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEP KDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQ HRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLV GHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGS RDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQ GHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGN ADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR NLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK |