Entrez Gene

Basic Information
Gene ID	55294
Name	FBXW7
Synonymous	AGO\|CDC4\|FBW6\|FBW7\|FBX30\|FBXO30\|FBXW6\|SEL-10\|SEL10\|hAgo\|hCdc4;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase;FBXW7;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
Definition	F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)\|F-box protein FBW7\|F-box protein FBX30\|F-box protein SEL-10\|F-box/WD repeat-containing protein 7\|archipelago\|homolog of C elegans sel-10
Position	4q31.3
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
Skp1(h) + Fbw7(h) <==> Skp1(h):Fbw7(h) (binding)
Cul-1(h) + Fbw7(h) <==> Cul-1(h):Fbw7(h) (binding)
cyclinE(m) + Fbw7(h) <==> cyclinE(m):Fbw7(h) (binding)
parkin(h) + Fbw7(h) <==> parkin(h):Fbw7(h) (binding)
Fbw7(h) + Skp1(v.s.) <==> Fbw7(h):Skp1(v.s.) (binding)
Fbw7(h) + cyclinE(v.s.) <==> Fbw7(h):cyclinE(v.s.) (binding)
Fbw7(h) + cyclinA1(v.s.) <==> Fbw7(h):cyclinA1(v.s.) (binding)
shprh(h) + Fbw7(h) <==> shprh(h):Fbw7(h) (binding)
Fbxw7(h) --> Fbw7(h) (expression).
parkin(h) + n ubiquitin(v.s.) --UbcH7(h),Fbw7(h)--> parkin(h){ub(n)} (ubiquitination)
Fbxw7(h) --> Fbw7-110k(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for FBXW7