Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5580

Name

PRKCD

Synonym

ALPS3|CVID9|MAY1|PKCD|nPKC-delta;protein kinase C, delta;PRKCD;protein kinase C, delta

Definition

protein kinase C delta VIII|protein kinase C delta type|tyrosine-protein kinase PRKCD

Position

3p21.31

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

538

TUSON P-value

0.012082641

Pathways and Diseases

Pathway

Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270

Pathway

Apoptosis;Reactome;REACT:578

Pathway

Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666

Pathway

Syndecan-4-mediated signaling events;PID Curated;200115

Pathway

Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027

Pathway

ErbB1 downstream signaling;PID Curated;200113

Pathway

Alpha-synuclein signaling;PID Curated;200187

Pathway

5HT2 type receptor mediated signaling pathway;PANTHER;P04374

Pathway

Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042

Pathway

Thyrotropin-releasing hormone receptor signaling pathway;PANTHER;P04394

Pathway

PDGFR-beta signaling pathway;PID Curated;200127

Pathway

FGF signaling pathway;PANTHER;P00021

Pathway

LPA receptor mediated events;PID Curated;200011

Pathway

Trk receptor signaling mediated by PI3K and PLC-gamma;PID Curated;200183

Pathway

p53 pathway;PID Curated;200175

Pathway

Opioid Signalling;Reactome;REACT:15295

Pathway

hiv-1 nef: negative effector of fas and tnf;PID BioCarta;100144

Pathway

Endothelin signaling pathway;PANTHER;P00019

Pathway

Apoptotic cleavage of cellular proteins;PID Reactome;500270

Pathway

Alpha adrenergic receptor signaling pathway;PANTHER;P00002

Pathway

EGF receptor signaling pathway;PANTHER;P00018

Pathway

Endothelins;PID Curated;200004

Pathway

Signalling by NGF;Reactome;REACT:11061

Pathway

IFN-gamma pathway;PID Curated;200110

Pathway

Hedgehog signaling events mediated by Gli proteins;PID Curated;200147

Pathway

Histamine H1 receptor mediated signaling pathway;PANTHER;P04385

Pathway

VEGF signaling pathway;PANTHER;P00056

Pathway

B cell activation;PANTHER;P00010

Pathway

Wnt signaling pathway;PANTHER;P00057

Pathway

Trk receptor signaling mediated by the MAPK pathway;PID Curated;200182

Pathway

Thromboxane A2 receptor signaling;PID Curated;200069

Pathway

Angiogenesis;PANTHER;P00005

Pathway

IGF1 pathway;PID Curated;200084

Pathway

GnRH signaling pathway;KEGG PATHWAY;hsa04912

Pathway

Alzheimer disease-amyloid secretase pathway;PANTHER;P00003

Pathway

Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664

Pathway

Oxytocin receptor mediated signaling pathway;PANTHER;P04391

Pathway

Hemostasis;Reactome;REACT:604

Pathway

Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076

Pathway

Ceramide signaling pathway;PID Curated;200100

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

Tight junction;KEGG PATHWAY;hsa04530

Pathway

Apoptosis signaling pathway;PANTHER;P00006

Pathway

IL6-mediated signaling events;PID Curated;200124

Pathway

Type II diabetes mellitus;KEGG PATHWAY;hsa04930

Pathway

Syndecan-2-mediated signaling events;PID Curated;200164

External Links

Links to Entrez Gene

5580

Links to all GeneRIF Items

5580

Links to iHOP

5580

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5580 : length: 2031
atggcgccgttcctgcgcatcgccttcaactcctatgagctgggctccctgcaggccgag
gacgaggcgaaccagcccttctgtgccgtgaagatgaaggaggcgctcagcacagagcgt
gggaaaacactggtgcagaagaagccgaccatgtatcctgagtggaagtcgacgttcgat
gcccacatctatgaggggcgcgtcatccagattgtgctaatgcgggcagcagaggagcca
gtgtctgaggtgaccgtgggtgtgtcggtgctggccgagcgctgcaagaagaacaatggc
aaggctgagttctggctggacctgcagcctcaggccaaggtgttgatgtctgttcagtat
ttcctggaggacgtggattgcaaacagtctatgcgcagtgaggacgaggccaagttccca
acgatgaaccgccgcggagccatcaaacaggccaaaatccactacatcaagaaccatgag
tttatcgccaccttctttgggcaacccaccttctgttctgtgtgcaaagactttgtctgg
ggcctcaacaagcaaggctacaaatgcaggcaatgtaacgctgccatccacaagaaatgc
atcgacaagatcatcggcagatgcactggcaccgcggccaacagccgggacactatattc
cagaaagaacgcttcaacatcgacatgccgcaccgcttcaaggttcacaactacatgagc
cccaccttctgtgaccactgcggcagcctgctctggggactggtgaagcagggattaaag
tgtgaagactgcggcatgaatgtgcaccataaatgccgggagaaggtggccaacctctgc
ggcatcaaccagaagcttttggctgaggccttgaaccaagtcacccagagagcctcccgg
agatcagactcagcctcctcagagcctgttgggatatatcagggtttcgagaagaagacc
ggagttgctggggaggacatgcaagacaacagtgggacctacggcaagatctgggagggc
agcagcaagtgcaacatcaacaacttcatcttccacaaggtcctgggcaaaggcagcttc
gggaaggtgctgcttggagagctgaagggcagaggagagtactttgccatcaaggccctc
aagaaggatgtggtcctgatcgacgacgacgtggagtgcaccatggttgagaagcgggtg
ctgacacttgccgcagagaatccctttctcacccacctcatctgcaccttccagaccaag
gaccacctgttctttgtgatggagttcctcaacgggggggacctgatgtaccacatccag
gacaaaggccgctttgaactctaccgtgccacgttttatgccgctgagataatgtgtgga
ctgcagtttctacacagcaagggcatcatttacagggacctcaaactggacaatgtgctg
ctggaccgggatggccacatcaagattgccgactttgggatgtgcaaagagaacatattc
ggggagagccgggccagcaccttctgcggcacccctgactatatcgcccctgagatccta
cagggcctgaagtacacattctctgtggactggtggtctttcggggtccttctgtacgag
atgctcattggccagtcccccttccatggtgatgatgaggatgaactcttcgagtccatc
cgtgtggacacgccacattatccccgctggatcaccaaggagtccaaggacatcctggag
aagctctttgaaagggaaccaaccaagaggctgggagtgaccggaaacatcaaaatccac
cccttcttcaagaccataaactggactctgctggaaaagcggaggttggagccacctttc
aggcccaaagtgaagtcacccagagactacagtaactttgaccaggagttcctgaacgag
aaggcgcgcctctcctacagcgacaagaacctcatcgactccatggaccagtctgcattc
gctggcttctcctttgtgaaccccaaattcgagcacctcctggaagattga

Protein Sequence

>5580 : length: 676
MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY
FLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASR
RSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIFHKVLGKGSF
GKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVL
LDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYE
MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIH
PFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAF
AGFSFVNPKFEHLLED



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