| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5601 |
Name | MAPK9 |
Synonym | JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK;mitogen-activated protein kinase 9;MAPK9;mitogen-activated protein kinase 9 |
Definition | Jun kinase|MAP kinase 9|MAPK 9|c-Jun N-terminal kinase 2|c-Jun kinase 2|stress-activated protein kinase 1a|stress-activated protein kinase JNK2 |
Position | 5q35 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 10319 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Regulation of retinoblastoma protein;PID Curated;200191 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Nephrin/Neph1 signaling in the kidney podocyte;PID Curated;200132 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | Interferon-gamma signaling pathway;PANTHER;P00035 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | Toll receptor signaling pathway;PANTHER;P00054 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621 |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | CD40/CD40L signaling;PID Curated;200031 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | FAS signaling pathway;PANTHER;P00020 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | ErbB2/ErbB3 signaling events;PID Curated;200119 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Rapid glucocorticoid signaling;PID Curated;200090 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Downstream signaling in naive CD8+ T cells;PID Curated;200184 |
Pathway | Epithelial cell signaling in Helicobacter pylori infection;KEGG PATHWAY;hsa05120 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | Alzheimer disease-amyloid secretase pathway;PANTHER;P00003 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | FAS (CD95) signaling pathway;PID Curated;200067 |
Pathway | Glypican 3 network;PID Curated;200193 |
Pathway | Oxidative stress response;PANTHER;P00046 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Type II diabetes mellitus;KEGG PATHWAY;hsa04930 |
Pathway | IL12 signaling mediated by STAT4;PID Curated;200197 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
|
External Links |
|
Links to Entrez Gene | 5601 |
Links to all GeneRIF Items | 5601 |
Links to iHOP | 5601 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5601 : length: 729 atgagcgacagtaaatgtgacagtcagttttatagtgtgcaagtggcagactcaaccttc actgtcctaaaacgttaccagcagctgaaaccaattggctctggggcccaagggattgtt tgtgctgcatttgatacagttcttgggataaatgttgcagtcaagaaactaagccgtcct tttcagaaccaaactcatgcaaagagagcttatcgtgaacttgtcctcttaaaatgtgtc aatcataaaaatataattagtttgttaaatgtgtttacaccacaaaaaactctagaagaa tttcaagatgtgtatttggttatggaattaatggatgctaacttatgtcaggttattcac atggagctggatcatgaaagaatgtcctaccttctttaccagatgctttgtggtattaaa catctgcattcagctggtataattcatagagatttgaagcctagcaacattgttgtgaaa tcagactgcaccctgaagatccttgactttggcctggcccggacagcgtgcactaacttc atgatgaccccttacgtggtgacacggtactaccgggcgcccgaagtcatcctgggtatg ggctacaaagagaacgttgatatctggtcagtgggttgcatcatgggagagctggtgaaa ggttgtgtgatattccaaggcactgaccgtatccttccccgcgaccttggccccgccatg ctttcttaa |
Protein Sequence |
>5601 : length: 242 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDRILPRDLGPAM LS |