| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5933 |
Name | RBL1 |
Synonym | CP107|PRB1|p107;retinoblastoma-like 1;RBL1;retinoblastoma-like 1 |
Definition | 107 kDa retinoblastoma-associated protein|cellular protein 107|retinoblastoma-like 1 (p107)|retinoblastoma-like protein 1 |
Position | 20q11.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 13893 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | cyclins and cell cycle regulation;PID BioCarta;100207 |
Pathway | mets affect on macrophage differentiation;PID BioCarta;100169 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Disease | Adenoma of thyroid;FunDO |
Disease | Breast cancer;FunDO |
Disease | Thyroid cancer;FunDO |
Disease | Papillary cancer;FunDO |
Disease | Prostate cancer;FunDO |
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External Links |
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Links to Entrez Gene | 5933 |
Links to all GeneRIF Items | 5933 |
Links to iHOP | 5933 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5933 : length: 3207 atgttcgaggacaagccccacgctgagggggcggcggtggtcgccgcagccggggaggcg ctacaggccctgtgccaggagctgaacctggacgaggggagcgcggccgaagccctggac gactttactgccatccgaggcaactacagcctagagggagaagttacacactggttggca tgttcattatatgttgcatgccgcaaaagcattattcccacggttggaaagggtatcatg gaaggcaactgtgtttcacttaccagaatactacgttcagctaaattaagtttaatacaa ttttttagtaaaatgaagaaatggatggacatgtcaaatctaccacaagaatttcgtgaa cgtatagaaaggctagagagaaattttgaggtgtctactgtaatattcaaaaaatatgag ccaatttttttagatatatttcaaaatccatatgaagaaccaccaaagttaccacgaagc cggaagcagaggaggattccttgcagtgttaaggatctgtttaatttctgttggacactt tttgtttatactaagggtaattttcggatgattggggatgacttagtaaactcttatcat ttacttctatgctgcttggatctgatttttgccaatgcgattatgtgcccaaatagacaa gacttgctaaatccatcatttaaaggtttaccatctgattttcatactgctgactttacg gcttctgaagagccaccctgcatcattgctgtactgtgtgaactgcatgatggacttctc gtagaagcaaaaggaataaaggagcactactttaagccatatatttcaaaactctttgac aggaagatattaaaaggagaatgcctcctggacctttcaagttttactgataatagcaaa gcagtgaataaggagtatgaagagtatgttctaactgttggtgattttgatgagaggatc tttttgggagcagacgcagaagaggaaattggaacacctcgaaagttcactcgtgacacc ccattagggaaactgacagcacaggctaatgtggagtataaccttcaacagcactttgaa aaaaaaaggtcatttgcaccttctaccccactgaccggacggagatatttacgagaaaaa gaagcagtcattactcctgttgcatcagccacccaaagtgtgagccggttacagagtatt gtggctggtctgaaaaatgcaccaagtgaccaacttataaatatttttgaatcttgtgtg cgtaatcctgtggaaaacattatgaaaatactaaaaggaataggagagactttctgtcaa cactatactcaatcaacagatgaacagccaggatctcacatagactttgctgtaaacaga ctaaagctggcagaaattttgtattataaaatactagagactgtaatggttcaggaaaca cgaagacttcatggaatggacatgtcagttcttttagagcaagatatatttcatcgttcc ttgatggcttgttgtttggaaattgtgctctttgcctatagctcacctcgtacttttcct tggattattgaagttctcaacttgcaaccattttacttttataaggttattgaggtggtg atccgctcagaagaggggctctcaagggacatggtgaaacacctaaacagcattgaagaa cagattttggagagtttagcatggagtcacgattctgcactgtgggaggctctccaggtt tctgcaaacaaagttcctacctgtgaagaagttatattcccaaataactttgaaacagga aatggaggaaatgtgcagggacatcttcccctgatgccaatgtctcctctaatgcaccca agagtcaaggaagttcgaactgacagtgggagtcttcgaagagatatgcaaccattgtct ccaatttctgtccatgaacgctacagttctcctaccgcagggagtgctaagagaagactc tttggagaggaccccccaaaggaaatgcttatggacaagatcataacagaaggaacaaaa ttgaaaatcgctccttcttcaagcattactgctgaaaatgtatcaattttacctggtcaa actcttctaacaatggccacagccccagtaacaggaacaacaggacataaagttacaatt ccattacatggtgtcgcaaatgatgctggagagatcacactgatacctctttccatgaat acaaatcaggagtccaaagtcaagagtcctgtatcacttactgctcattcattaattggt gcttctccaaaacagaccaatctgactaaagcacaagaggtacattcaactggaataaac aggccaaagagaactgggtccttagcactattttacagaaaggtctatcatttggcaagt gtacgcttacgtgatctatgtctaaaactggatgtttcaaatgagttacgaaggaagata tggacgtgttttgaattcactttagttcactgtcctgatctaatgaaagacaggcatttg gatcagctcctcctttgtgccttttatatcatggcaaaggtaacaaaagaagaaagaact tttcaagaaattatgaaaagttataggaatcagccccaagctaatagtcacgtatataga agtgttctgctgaaaagtattccaagagaagttgtggcatataataaaaatataaatgat gactttgaaatgatagattgtgacttagaagatgctacaaaaacacctgactgttccagt ggaccagtgaaagaggaaagaggtgatcttataaaattttacaatacaatatatgtagga agagtgaagtcatttgcactgaaatacgacttggcgaatcaggaccatatgatggatgct ccaccactctctccttttccacatattaaacaacagccaggctcaccacgccgcatttcc cagcagcactccatttatatttccccgcacaagaatgggtcaggccttacaccaagaagc gctctgctgtacaagttcaatggcagcccttctaagagtttgaaagatatcaacaacatg ataaggcaaggtgagcagagaaccaagaagcgagtaatagccatcgatagtgatgcagaa tcccctgccaaacgcgtctgtcaagaaaatgatgacgttttactgaaacgactacaggat gttgtcagtgaaagagcaaatcattaa |
Protein Sequence |
>5933 : length: 1068 MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLA CSLYVACRKSIIPTVGKGIMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRE RIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFT ASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGECLLDLSSFTDNSK AVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCV RNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQET RRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETG NGGNVQGHLPLMPMSPLMHPRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRL FGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGIN RPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHL DQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPREVVAYNKNIND DFEMIDCDLEDATKTPDCSSGPVKEERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDA PPLSPFPHIKQQPGSPRRISQQHSIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNM IRQGEQRTKKRVIAIDSDAESPAKRVCQENDDVLLKRLQDVVSERANH |