| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5933 |
Name | RBL1 |
Synonymous | CP107|PRB1|p107;retinoblastoma-like 1;RBL1;retinoblastoma-like 1 |
Definition | 107 kDa retinoblastoma-associated protein|cellular protein 107|retinoblastoma-like 1 (p107)|retinoblastoma-like protein 1 |
Position | 20q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
p107(h) + cyclinA(h):Cdk2(h) <==> p107(h):cyclinA(h):Cdk2(h) (binding) | p107(h) + cyclinE(h):Cdk2(h) <==> p107(h):cyclinE(h):Cdk2(h) (binding) | E1A(12S)(AD12) + p107(h) + p130(h) + pRb(h) + p300(h) <==> E1A(12S)(AD12):p300(h):pRb(h):p130(h):p107(h) (binding) | p107(h) --> DHFR(ha) (DNA binding). | DP-2(h) + p107(h) <==> DP-2(h):p107(h) (binding) | DP-1(h) + p107(h) <==> DP-1(h):p107(h) (binding) | E2F-5(h):DP-1(h) + p107(h) <==> E2F-5(h):DP-1(h):p107(h) (binding) | E2F-4(h) + p107(h) <==> E2F-4(h):p107(h) (binding) | E2F-4(h):DP-1(h) + p107(h) <==> E2F-4(h):DP-1(h):p107(h) (binding) | p107(h) + p202(m) <==> p107(h):p202(m) (binding) | c-Myc(h) + p107(h) <==> c-Myc(h):p107(h) (binding). | p107(h) + T-Ag(SV) <==> p107(h):T-Ag(SV) (binding). | E2F-5(h) + p107(h) <==> E2F-5(h):p107(h) (binding). | Sp1(h) + p107(h) <==> Sp1(h):p107(h) (binding). | E2F(h):DP(h) + p107(h) <==> E2F(h):DP(h):p107(h) (binding). | cyclinA(h) + p107(h) <==> cyclinA(h):p107(h) (binding). | E1A 13S protein(AD2) + p107(h) <==> E1A 13S protein(AD2):p107(h) (binding). | p107(h) + E1A(AD) <==> p107(h):E1A(AD) (binding) | p107(h) + RBBP1(h) <==> p107(h):RBBP1(h) (binding) | HDAC1(h) + p107(h) <==> HDAC1(h):p107(h) (binding) | p107(h) + hdac2(h) <==> p107(h):hdac2(h) (binding) | p107(h) + HDAC3(h) <==> p107(h):HDAC3(h) (binding) | CtIP(h) + p107(h) <==> CtIP(h):p107(h) (binding) | p107(h) + begain(h) <==> p107(h):begain(h) (binding) | p107(h) --> Abcc10(h) (DNA binding). | p107(h) + Cdk2(h) <==> p107(h):Cdk2(h) (binding) | RBL1(h) --> p107(h) (expression). | HCV-NS5B-1B-Japanese(HCV1BJapan) --> p107(h) (increase of abundance) | RBL1(h) --> p107-xbb1(h) (expression). | RBL1(h) --> p107-isoform1(h) (expression). | RBL1(h) --> p107-isoform2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
332 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 369 | Phosphothreonine (by CDK4). | Swiss-Prot 53.0 | 385 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 640 | Phosphoserine (by CDK2 and CDK4). | Swiss-Prot 53.0 | 650 | Phosphoserine. | Swiss-Prot 53.0 | 762 | Phosphoserine (by CDK2). | Swiss-Prot 53.0 | 964 | Phosphoserine (by CDK2 and CDK4). | Swiss-Prot 53.0 | 975 | Phosphoserine (by CDK2 and CDK4). | Swiss-Prot 53.0 | 988 | Phosphoserine (by CDK2). | Swiss-Prot 53.0 | 997 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 1009 | Phosphoserine (by CDK2). | Swiss-Prot 53.0 | 369 | Phosphothreonine (CDK4) | 12006580 | Phospho.ELM 6.0 | 340 | Phosphothreonine | 12006580 | Phospho.ELM 6.0 | 332 | Phosphothreonine | 12006580 | Phospho.ELM 6.0 | 997 | Phosphothreonine | 12006580 | Phospho.ELM 6.0 | 762 | Phosphoserine | 12006580 | Phospho.ELM 6.0 | 749 | Phosphoserine | 12006580 | Phospho.ELM 6.0 | 650 | Phosphoserine (CDK4) | 12006580 | Phospho.ELM 6.0 | 640 | Phosphoserine (CDK4) | 12006580;11884610 | Phospho.ELM 6.0 | 615 | Phosphoserine | 12006580 | Phospho.ELM 6.0 | 1041 | Phosphoserine | 12006580 | Phospho.ELM 6.0 | 1009 | Phosphoserine | 12006580 | Phospho.ELM 6.0 | 988 | Phosphoserine | 12006580 | Phospho.ELM 6.0 | 975 | Phosphoserine (CDK4) | 12006580;11884610;10069453 | Phospho.ELM 6.0 | 964 | Phosphoserine (CDK4) | 12006580 | Phospho.ELM 6.0 | 385 | Phosphothreonine | 12006580 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr20 |
Promoter: 35157324 - 35159324 | Agilent_014791 |
chr20 |
Promoter: 35157324 - 35159324 | GSE27584 |
chr20 |
Promoter: 35157324 - 35159324 | GSE27584 |
chr20 |
Promoter: 35157324 - 35159324 | Agilent_014791_44K |