| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5934 |
Name | RBL2 |
Synonym | P130|Rb2;retinoblastoma-like 2;RBL2;retinoblastoma-like 2 |
Definition | 130 kDa retinoblastoma-associated protein|PRB2|RBR-2|retinoblastoma-like protein 2|retinoblastoma-related protein 2 |
Position | 16q12.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 1175 |
TUSON P-value | 0.058782066 |
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Pathways and Diseases |
|
Pathway | mets affect on macrophage differentiation;PID BioCarta;100169 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 5934 |
Links to all GeneRIF Items | 5934 |
Links to iHOP | 5934 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5934 : length: 3420 atgccgtcgggaggtgaccagtcgccaccgcccccgcctccccctccggcggcggcagcc tcggatgaggaggaggaggacgacggcgaggcggaagacgccgcgccgcctgccgagtcg cccacccctcagatccagcagcggttcgacgagctgtgcagccgcctcaacatggacgag gcggcgcgggccgaggcctgggacagctaccgcagcatgagcgaaagctacacgctggag ggaaatgatcttcattggttagcatgtgccttatatgtggcttgcagaaaatctgttcca actgtaagcaaagggacagtggaaggaaactatgtatctttaactagaatcctgaaatgt tcagagcagagcttaatcgaattttttaataagatgaagaagtgggaagacatggcaaat ctacccccacatttcagagaacgtactgagagattagaaagaaacttcactgtttctgct gtaatttttaagaaatatgaacccatttttcaggacatctttaaataccctcaagaggag caacctcgtcagcagcgaggaaggaaacagcggcgacagccctgtactgtgtctgaaatt ttccatttttgttgggtgctttttatatatgcaaaaggtaatttccccatgattagtgat gatttggtcaattcttatcacctgctgctgtgtgctttggacttagtttatggaaatgca cttcagtgttctaatcgtaaagaacttgtgaaccctaattttaaaggcttatctgaagat tttcatgctaaagattctaaaccttcctctgaccccccttgtatcattgagaaactgtgt tccttacatgatggcctagttttggaagcaaaggggataaaggaacatttctggaaaccc tatattaggaaactttatgaaaaaaagctccttaagggaaaagaagaaaatctcactggg tttctagaacctgggaactttggagagagttttaaagccatcaataaggcctatgaggag tatgttttatctgttgggaatttagatgagcggatatttcttggagaggatgctgaggag gaaattgggactctctcaaggtgtctgaacgctggttcaggaacagagactgctgaaagg gtgcagatgaaaaacatcttacagcagcattttgacaagtccaaagcacttagaatctcc acaccactaactggtgttaggtacattaaggagaatagcccttgtgtgactccagtttct acagctacgcatagcttgagtcgtcttcacaccatgctgacaggcctcaggaatgcacca agtgagaaactggaacagattctcaggacatgttccagagatccaacccaggctattgct aacagactgaaagaaatgtttgaaatatattctcagcatttccagccagacgaggatttc agtaattgtgctaaagaaattgccagcaaacattttcgttttgcggagatgctttactat aaagtattagaatctgttattgagcaggaacaaaaaagactaggagacatggatttatct ggtattctggaacaagatgcgttccacagatctctcttggcctgctgccttgaggtcgtc actttttcttataagcctcctgggaattttccatttattactgaaatatttgatgtgcct ctttatcatttttataaggtgatagaagtattcattagagcagaagatggcctttgtaga gaggtggtaaaacaccttaatcagattgaagaacagatcttagatcatttggcatggaaa ccagagtctccactctgggaaaaaattagagacaatgaaaacagagttcctacatgtgaa gaggtcatgccacctcagaacctggaaagggcagatgaaatttgcattgctggctcccct ttgactcccagaagggtgactgaagttcgtgctgatactggaggacttggaaggagcata acatctccaaccacattatacgataggtacagctccccaccagccagcactaccagaagg cggctatttgttgagaatgatagcccctctgatggagggacgcctgggcgcatgccccca cagcccctagtcaatgctgtccctgtgcagaatgtatctggggagactgtttctgtcaca ccagttcctggacagactttggtcaccatggcaaccgccactgtcacagccaacaatggg caaacggtaaccattcctgtgcaaggtattgccaatgaaaatggagggataacattcttc cctgtccaagtcaatgttggggggcaggcacaagctgtgacaggctccatccagcccctc agtgctcaggccctggctggaagtctgagctctcaacaggtgacaggaacaactttgcaa gtccctggtcaagtggccattcaacagatttccccaggtggccaacagcagaagcaaggc cagtctgtaaccagcagtagtaatagacccaggaagaccagctctttatcgcttttcttt agaaaggtataccatttagcagctgtccgccttcgggatctctgtgccaaactagatatt tcagatgaattgaggaaaaaaatctggacctgctttgaattctccataattcagtgtcct gaacttatgatggacagacatctggaccagttattaatgtgtgccatttatgtgatggca aaggtcacaaaagaagataagtccttccagaacattatgcgttgttataggactcagccg caggcccggagccaggtgtatagaagtgttttgataaaagggaaaagaaaaagaagaaat tctggcagcagtgatagcagaagccatcagaattctccaacagaactaaacaaagataga accagtagagactccagtccagttatgaggtcaagcagcaccttgccagttccacagccc agcagtgctcctcccacacctactcgcctcacaggtgccaacagtgacatggaagaagag gagaggggagacctcattcagttctacaacaacatctacatcaaacagattaagacattt gccatgaagtactcacaggcaaatatggatgctcctccactctctccctatccatttgta agaacaggctcccctcgccgaatacagttgtctcaaaatcatcctgtctacatttcccca cataaaaatgaaacaatgctttctcctcgagaaaagattttctattacttcagcaacagt ccttcaaagagactgagagaaattaatagtatgatacgcacaggagaaactcctactaaa aagagaggaattcttttggaagatggaagtgaatcacctgcaaaaagaatttgcccagaa aatcattctgccttattacgccgtctccaagatgtagctaatgaccgtggttcccactga |
Protein Sequence |
>5934 : length: 1139 MPSGGDQSPPPPPPPPAAAASDEEEEDDGEAEDAAPPAESPTPQIQQRFDELCSRLNMDE AARAEAWDSYRSMSESYTLEGNDLHWLACALYVACRKSVPTVSKGTVEGNYVSLTRILKC SEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEE QPRQQRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNA LQCSNRKELVNPNFKGLSEDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWKP YIRKLYEKKLLKGKEENLTGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAEE EIGTLSRCLNAGSGTETAERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTPVS TATHSLSRLHTMLTGLRNAPSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQPDEDF SNCAKEIASKHFRFAEMLYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCLEVV TFSYKPPGNFPFITEIFDVPLYHFYKVIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWK PESPLWEKIRDNENRVPTCEEVMPPQNLERADEICIAGSPLTPRRVTEVRADTGGLGRSI TSPTTLYDRYSSPPASTTRRRLFVENDSPSDGGTPGRMPPQPLVNAVPVQNVSGETVSVT PVPGQTLVTMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGGQAQAVTGSIQPL SAQALAGSLSSQQVTGTTLQVPGQVAIQQISPGGQQQKQGQSVTSSSNRPRKTSSLSLFF RKVYHLAAVRLRDLCAKLDISDELRKKIWTCFEFSIIQCPELMMDRHLDQLLMCAIYVMA KVTKEDKSFQNIMRCYRTQPQARSQVYRSVLIKGKRKRRNSGSSDSRSHQNSPTELNKDR TSRDSSPVMRSSSTLPVPQPSSAPPTPTRLTGANSDMEEEERGDLIQFYNNIYIKQIKTF AMKYSQANMDAPPLSPYPFVRTGSPRRIQLSQNHPVYISPHKNETMLSPREKIFYYFSNS PSKRLREINSMIRTGETPTKKRGILLEDGSESPAKRICPENHSALLRRLQDVANDRGSH |