Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5934

Name

RBL2

Synonymous

P130|Rb2;retinoblastoma-like 2;RBL2;retinoblastoma-like 2

Definition

130 kDa retinoblastoma-associated protein|PRB2|RBR-2|retinoblastoma-like protein 2|retinoblastoma-related protein 2

Position

16q12.2

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 CDK2REACTOME;

in same component

 CKS1BREACTOME;

in same component

 CUL1REACTOME;

in same component

 E2F4CELL_MAP;

in same component

 E2f5CELL_MAP;

in same component

 HDAC1REACTOME;

in same component

 LIN37REACTOME;

in same component

 LIN52REACTOME;

in same component

 LIN54REACTOME;

in same component

 LIN9REACTOME;

in same component

 RBBP4REACTOME;

in same component

 SKP1REACTOME;

in same component

 SKP2REACTOME;

interacts with

 AATFBIOGRID;

interacts with

 ABD1MINT;

interacts with

 ACC1MINT;

interacts with

 ACM1MINT;

interacts with

 AGE1MINT;

interacts with

 AGE2MINT;

interacts with

 AIM21MINT;

interacts with

 AKL1MINT;

interacts with

 ALD6MINT;

interacts with

 ALK1MINT;

interacts with

 ALY2MINT;

interacts with

 APM4MINT;

interacts with

 ARK1MINT;

interacts with

 ARP3MINT;

interacts with

 ART5MINT;

interacts with

 ASK10MINT;

interacts with

 ATG11MINT;

interacts with

 ATG13MINT;

interacts with

 AVT4MINT;

interacts with

 BBP1MINT;

interacts with

 BCK1MINT;

interacts with

 BCK2MINT;

interacts with

 BFA1MINT;

interacts with

 BIM1MINT;

interacts with

 BMH1MINT;

interacts with

 BMH2MINT;

interacts with

 BNI4MINT;

interacts with

 BNI5MINT;

interacts with

 BNR1MINT;

interacts with

 BOI1MINT;

interacts with

 BOI2MINT;

interacts with

 BOP3MINT;

interacts with

 BRCA1BIOGRID;

interacts with

 BRF1BIOGRID;

interacts with

 BRF1HPRD;

interacts with

 BRF2HPRD;

interacts with

 BUB2MINT;

interacts with

 BUL1MINT;

interacts with

 BUL2MINT;

interacts with

 CCNA1BIOGRID;

interacts with

 CCNA2BIOGRID;

interacts with

 CCNA2HPRD;

interacts with

 CCND1HPRD;

interacts with

 CCND3HPRD;

interacts with

 CCNE1BIOGRID;

interacts with

 CCNE1HPRD;

interacts with

 CDC14BIOGRID;

interacts with

 CDC14MINT;

interacts with

 CDC25MINT;

interacts with

 CDH1MINT;

interacts with

 CDK2BIOGRID;

interacts with

 CDK2HPRD;

interacts with

 CDK4HPRD;

interacts with

 CDK6HPRD;

interacts with

 CIK1MINT;

interacts with

 CIN8MINT;

interacts with

 CKA1MINT;

interacts with

 CKA2MINT;

interacts with

 CKI1MINT;

interacts with

 CREG1HPRD;

interacts with

 CRG1MINT;

interacts with

 CSR2MINT;

interacts with

 CUL1BIOGRID;

interacts with

 CYK3MINT;

interacts with

 CYR1MINT;

interacts with

 DED1MINT;

interacts with

 DGKZHPRD;

interacts with

 DIG1MINT;

interacts with

 DIG2MINT;

interacts with

 DNMT1HPRD;

interacts with

 DOT6MINT;

interacts with

 DSF2MINT;

interacts with

 E2F4BIOGRID;

interacts with

 E2F4CELL_MAP;

interacts with

 E2F4HPRD;

interacts with

 E2F5BIOGRID;

interacts with

 E2F5CELL_MAP;

interacts with

 E2F5HPRD;

interacts with

 ECM21MINT;

interacts with

 EFR3MINT;

interacts with

 ENT4MINT;

interacts with

 EP300HPRD;

interacts with

 ERB1MINT;

interacts with

 ERG3MINT;

interacts with

 EZH2BIOGRID;

interacts with

 FIN1MINT;

interacts with

 FIR1MINT;

interacts with

 FLD1MINT;

interacts with

 FLO8MINT;

interacts with

 FPK1MINT;

interacts with

 FRK1MINT;

interacts with

 FRQ1MINT;

interacts with

 FRT1MINT;

interacts with

 GAL4MINT;

interacts with

 GAT1MINT;

interacts with

 GCR2MINT;

interacts with

 GIC2MINT;

interacts with

 GIN4MINT;

interacts with

 GIP2MINT;

interacts with

 GIP3MINT;

interacts with

 GIP4MINT;

interacts with

 GIS2BIOGRID;

interacts with

 GIS4MINT;

interacts with

 GLC7MINT;

interacts with

 GLN3MINT;

interacts with

 GTS1MINT;

interacts with

 HAA1MINT;

interacts with

 HAL5MINT;

interacts with

 HBP1BIOGRID;

interacts with

 HBP1HPRD;

interacts with

 HDAC1BIOGRID;

interacts with

 HER1MINT;

interacts with

 HLR1MINT;

interacts with

 HOF1MINT;

interacts with

 HOT1MINT;

interacts with

 HRK1MINT;

interacts with

 HRR25MINT;

interacts with

 HYM1MINT;

interacts with

 ID2BIOGRID;

interacts with

 ID2HPRD;

interacts with

 Ifi205bMINT;

interacts with

 ILV6MINT;

interacts with

 IML3MINT;

interacts with

 IMP2'MINT;

interacts with

 INN1MINT;

interacts with

 INP53MINT;

interacts with

 IPP1MINT;

interacts with

 IRC20MINT;

interacts with

 IRC3MINT;

interacts with

 JIP4MINT;

interacts with

 JSN1BIOGRID;

interacts with

 JSN1MINT;

interacts with

 KAR2MINT;

interacts with

 KAR3MINT;

interacts with

 KCS1MINT;

interacts with

 KIN1MINT;

interacts with

 KIN2MINT;

interacts with

 KIN4MINT;

interacts with

 KIN82MINT;

interacts with

 KIP2MINT;

interacts with

 KKQ8MINT;

interacts with

 KSP1MINT;

interacts with

 LAT1MINT;

interacts with

 LDB16MINT;

interacts with

 LEU2MINT;

interacts with

 LHS1MINT;

interacts with

 LIN54MINT;

interacts with

 LIN9HPRD;

interacts with

 LRE1MINT;

interacts with

 LSC1MINT;

interacts with

 LSP1MINT;

interacts with

 LST4MINT;

interacts with

 MAF1MINT;

interacts with

 MCM10MINT;

interacts with

 MCM7BIOGRID;

interacts with

 MDS3MINT;

interacts with

 MET18MINT;

interacts with

 MHP1MINT;

interacts with

 MIG1MINT;

interacts with

 MKS1MINT;

interacts with

 MLF3MINT;

interacts with

 MNDAHPRD;

interacts with

 MPC54MINT;

interacts with

 MPT5MINT;

interacts with

 MSB1MINT;

interacts with

 MSB3MINT;

interacts with

 MSC3MINT;

interacts with

 MSG5MINT;

interacts with

 MSN2MINT;

interacts with

 MSN4MINT;

interacts with

 MSO1MINT;

interacts with

 MSS4MINT;

interacts with

 NAB2BIOGRID;

interacts with

 NAM7MINT;

interacts with

 NAP1MINT;

interacts with

 NNK1MINT;

interacts with

 NPR1MINT;

interacts with

 NTE1MINT;

interacts with

 NTH1MINT;

interacts with

 NTH2MINT;

interacts with

 NUG1MINT;

interacts with

 NUP60MINT;

interacts with

 OSH2MINT;

interacts with

 PAM1MINT;

interacts with

 PBS2MINT;

interacts with

 PCBD1BIOGRID;

interacts with

 PEF1MINT;

interacts with

 PFK26MINT;

interacts with

 PHBBIOGRID;

interacts with

 PHBHPRD;

interacts with

 PHO87MINT;

interacts with

 PIK1MINT;

interacts with

 PIL1MINT;

interacts with

 PKH2MINT;

interacts with

 PMD1MINT;

interacts with

 PPP2CABIOGRID;

interacts with

 PPS1MINT;

interacts with

 PPZ2MINT;

interacts with

 PRK1MINT;

interacts with

 PRR1MINT;

interacts with

 PSK1MINT;

interacts with

 PSK2MINT;

interacts with

 PSP1MINT;

interacts with

 PTK1MINT;

interacts with

 PTK2MINT;

interacts with

 PTP3MINT;

interacts with

 PUF2MINT;

interacts with

 PUF3MINT;

interacts with

 PXL1MINT;

interacts with

 RAF1BIOGRID;

interacts with

 RAF1HPRD;

interacts with

 RAI1MINT;

interacts with

 RAM1MINT;

interacts with

 RB1BIOGRID;

interacts with

 RBBP8BIOGRID;

interacts with

 RBBP8HPRD;

interacts with

 RBBP8MINT;

interacts with

 RBBP9BIOGRID;

interacts with

 RBBP9HPRD;

interacts with

 RCN2MINT;

interacts with

 RDS1MINT;

interacts with

 REG1MINT;

interacts with

 RGA2MINT;

interacts with

 RGC1MINT;

interacts with

 RIM4MINT;

interacts with

 RINT1HPRD;

interacts with

 RKI1BIOGRID;

interacts with

 ROD1MINT;

interacts with

 ROG3MINT;

interacts with

 ROM2MINT;

interacts with

 ROX1MINT;

interacts with

 RPS3MINT;

interacts with

 RRM3MINT;

interacts with

 RSP5MINT;

interacts with

 RTG2MINT;

interacts with

 RTS3MINT;

interacts with

 RTT102MINT;

interacts with

 SAC7MINT;

interacts with

 SAM50MINT;

interacts with

 SAP1MINT;

interacts with

 SBE22MINT;

interacts with

 SEC16MINT;

interacts with

 SEC1MINT;

interacts with

 SEF1MINT;

interacts with

 SERPINB2BIOGRID;

interacts with

 SFL1MINT;

interacts with

 SHE1MINT;

interacts with

 SIR4MINT;

interacts with

 SIS1MINT;

interacts with

 SKP1BIOGRID;

interacts with

 SKP2BIOGRID;

interacts with

 SKT5MINT;

interacts with

 SLA1MINT;

interacts with

 SLX4MINT;

interacts with

 SNF1MINT;

interacts with

 SNT1MINT;

interacts with

 SNW1BIOGRID;

interacts with

 SNW1HPRD;

interacts with

 SOK1MINT;

interacts with

 SPC110MINT;

interacts with

 SPC29MINT;

interacts with

 SPO71MINT;

interacts with

 SPT6MINT;

interacts with

 SRL3MINT;

interacts with

 SRV2MINT;

interacts with

 SSA1MINT;

interacts with

 SSA2MINT;

interacts with

 SSA3MINT;

interacts with

 SSA4MINT;

interacts with

 SSB1MINT;

interacts with

 SSB2MINT;

interacts with

 SSD1MINT;

interacts with

 STB2MINT;

interacts with

 STB6MINT;

interacts with

 STU1MINT;

interacts with

 SUV39H1BIOGRID;

interacts with

 SUV39H1HPRD;

interacts with

 SUV420H2HPRD;

interacts with

 SVL3MINT;

interacts with

 SWP82MINT;

interacts with

 SYT1MINT;

interacts with

 TAF1BIOGRID;

interacts with

 TAF1HPRD;

interacts with

 TCO89MINT;

interacts with

 TDA2MINT;

interacts with

 TDH2MINT;

interacts with

 TDH3MINT;

interacts with

 TFDP1CELL_MAP;

interacts with

 TFDP1HPRD;

interacts with

 TGL4MINT;

interacts with

 TOD6MINT;

interacts with

 TSA1MINT;

interacts with

 TUB2BIOGRID;

interacts with

 UBP12MINT;

interacts with

 UBTFHPRD;

interacts with

 UME6MINT;

interacts with

 URA2MINT;

interacts with

 USP4BIOGRID;

interacts with

 UTP6MINT;

interacts with

 VAC17MINT;

interacts with

 VHS2MINT;

interacts with

 WHI3MINT;

interacts with

 WHI4MINT;

interacts with

 XBP1BIOGRID;

interacts with

 XBP1MINT;

interacts with

 YAK1MINT;

interacts with

 YEL1MINT;

interacts with

 YOX1MINT;

interacts with

 YSC84MINT;

interacts with

 YSH1MINT;

interacts with

 YSP2MINT;

interacts with

 YTA6MINT;

interacts with

 ZAP1MINT;

interacts with

 ZDS1MINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 FOXO3NCI_NATURE;

metabolic catalysis

 FOXO4NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CDK2REACTOME;

reacts with

 CKS1BREACTOME;

reacts with

 CUL1REACTOME;

reacts with

 E2F4CELL_MAP;

reacts with

 E2f5CELL_MAP;

reacts with

 HDAC1REACTOME;

reacts with

 LIN37REACTOME;

reacts with

 LIN52REACTOME;

reacts with

 LIN54REACTOME;

reacts with

 LIN9REACTOME;

reacts with

 RBBP4REACTOME;

reacts with

 RBL2CELL_MAP;

reacts with

 RBL2REACTOME;

reacts with

 SKP1REACTOME;

reacts with

 SKP2REACTOME;

state change

 CCND1CELL_MAP;

state change

 CDK4CELL_MAP;

state change

 CDK6CELL_MAP;

state change

 CKS1BREACTOME;

state change

 CUL1REACTOME;

state change

 RBL2REACTOME;

state change

 SKP1REACTOME;

state change

 SKP2REACTOME;

')