| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6477 |
Name | SIAH1 |
Synonym | SIAH1A;siah E3 ubiquitin protein ligase 1;SIAH1;siah E3 ubiquitin protein ligase 1 |
Definition | E3 ubiquitin-protein ligase SIAH1|seven in absentia homolog 1|siah-1a |
Position | 16q12.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 14928 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Netrin-1 signaling;PID Reactome;500088 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Disease | Pancreas cancer;FunDO |
Disease | Liver cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Parkinson disease;FunDO |
|
External Links |
|
Links to Entrez Gene | 6477 |
Links to all GeneRIF Items | 6477 |
Links to iHOP | 6477 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6477 : length: 942 atgacgggaaaggctactccaccttctctgtactcctggaggggagtcttgttcacatgt ttaccagcggccaggacaaggaagagaaaagaaatgagccgtcagactgctacagcatta cctaccggtacctcgaagtgtccaccatcccagagggtgcctgccctgactggcacaact gcatccaacaatgacttggcgagtctttttgagtgtccagtctgctttgactatgtgtta ccgcccattcttcaatgtcagagtggccatcttgtttgtagcaactgtcgcccaaagctc acatgttgtccaacttgccggggccctttgggatccattcgcaacttggctatggagaaa gtggctaattcagtacttttcccctgtaaatatgcgtcttctggatgtgaaataactctg ccacacacagaaaaagcagaccatgaagagctctgtgagtttaggccttattcctgtccg tgccctggtgcttcctgtaaatggcaaggctctctggatgctgtaatgccccatctgatg catcagcataagtccattacaaccctacagggagaggatatagtttttcttgctacagac attaatcttcctggtgctgttgactgggtgatgatgcagtcctgttttggctttcacttc atgttagtcttagagaaacaggaaaaatacgatggtcaccagcagttcttcgcaatcgta cagctgataggaacacgcaagcaagctgaaaattttgcttaccgacttgagctaaatggt cataggcgacgattgacttgggaagcgactcctcgatctattcatgaaggaattgcaaca gccattatgaatagcgactgtctagtctttgacaccagcattgcacagctttttgcagaa aatggcaatttaggcatcaatgtaactatttccatgtgttga |
Protein Sequence |
>6477 : length: 313 MTGKATPPSLYSWRGVLFTCLPAARTRKRKEMSRQTATALPTGTSKCPPSQRVPALTGTT ASNNDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEK VANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLM HQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIV QLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAE NGNLGINVTISMC |