Entrez Gene

Basic Information
Gene ID	6477
Name	SIAH1
Synonymous	SIAH1A;siah E3 ubiquitin protein ligase 1;SIAH1;siah E3 ubiquitin protein ligase 1
Definition	E3 ubiquitin-protein ligase SIAH1\|seven in absentia homolog 1\|siah-1a
Position	16q12.1
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
apc(h) + Siah1(h) <==> apc(h):Siah1(h) (binding)
Siah1(h) + SIAHBP1(h) <==> Siah1(h):SIAHBP1(h) (binding)
Siah1(h) + SIP-S(h) <==> Siah1(h):SIP-S(h) (binding)
Siah1(h) + SIAHBP1(h) + Skp1(h) <==> Siah1(h):SIAHBP1(h):Skp1(h) (binding)
Ebi(h) + Siah1(h) + SIAHBP1(h) + Skp1(h) <==> Ebi(h):Skp1(h):Siah1(h):SIAHBP1(h) (binding)
bag1(m) + Siah1(h) <==> bag1(m):Siah1(h) (binding)
2 Siah1(h) <==> Siah1(h):Siah1(h) (binding)
Siah1(h) + Ubc9(h) <==> Siah1(h):Ubc9(h) (binding)
Siah1(h) --/ DCC(h) (degradation)
Numb(h) + Siah1(h) <==> Numb(h):Siah1(h) (binding)
Siah1(h) + Synphilin-1(h) <==> Siah1(h):Synphilin-1(h) (binding)
Siah1(h) + synphilin-1(r) <==> Siah1(h):synphilin-1(r) (binding)
Siah1(h) + n ubiquitin(v.s.) --> Siah1(h){ub(n)} (ubiquitination)
Kid(m.s.) + Siah1(h) <==> Kid(m.s.):Siah1(h) (binding)
Siah1(h) + SLM2(h) <==> Siah1(h):SLM2(h) (binding)
Siah1(h) + aff4(h) <==> Siah1(h):aff4(h) (binding)
p53(h) --> Siah1(h) (activation)
SIAH1(h) --> Siah1(h) (expression).
Synphilin-1(h) + n ubiquitin(v.s.) --Siah1(h),ATP--> Synphilin-1(h){ub(n)} (ubiquitination)
Synphilin-1(h) + n ubiquitin(v.s.) --ATP,E1(v.s.),Ubc5B(h),Siah1(h)--> Synphilin-1(h){ub(n)} (ubiquitination)
SIAH1(h) --> Siah1-isoform1(h) (expression).
SIAH1(h) --> Siah1-isoform2(h) (expression).
SIAH1(h) --> Siah1-isoform3(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for SIAH1