| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6678 |
Name | SPARC |
Synonym | ON;secreted protein, acidic, cysteine-rich (osteonectin);SPARC;secreted protein, acidic, cysteine-rich (osteonectin) |
Definition | BM-40|basement-membrane protein 40|cysteine-rich protein|osteonectin|secreted protein acidic and rich in cysteine |
Position | 5q31.3-q32 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 15596 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Hemostasis;Reactome;REACT:604 |
Disease | Alveolar bone loss;FunDO |
Disease | IMMUNE;GAD |
Disease | Cancer;FunDO |
Disease | Gingival overgrowth;FunDO |
Disease | scleroderma;GAD |
|
External Links |
|
Links to Entrez Gene | 6678 |
Links to all GeneRIF Items | 6678 |
Links to iHOP | 6678 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6678 : length: 912 atgagggcctggatcttctttctcctttgcctggccgggagggccttggcagcccctcag caagaagccctgcctgatgagacagaggtggtggaagaaactgtggcagaggtgactgag gtatctgtgggagctaatcctgtccaggtggaagtaggagaatttgatgatggtgcagag gaaaccgaagaggaggtggtggcggaaaatccctgccagaaccaccactgcaaacacggc aaggtgtgcgagctggatgagaacaacacccccatgtgcgtgtgccaggaccccaccagc tgcccagcccccattggcgagtttgagaaggtgtgcagcaatgacaacaagaccttcgac tcttcctgccacttctttgccacaaagtgcaccctggagggcaccaagaagggccacaag ctccacctggactacatcgggccttgcaaatacatccccccttgcctggactctgagctg accgaattccccctgcgcatgcgggactggctcaagaacgtcctggtcaccctgtatgag agggatgaggacaacaaccttctgactgagaagcagaagctgcgggtgaagaagatccat gagaatgagaagcgcctggaggcaggagaccaccccgtggagctgctggcccgggacttc gagaagaactataacatgtacatcttccctgtacactggcagttcggccagctggaccag caccccattgacgggtacctctcccacaccgagctggctccactgcgtgctcccctcatc cccatggagcattgcaccacccgctttttcgagacctgtgacctggacaatgacaagtac atcgccctggatgagtgggccggctgcttcggcatcaagcagaaggatatcgacaaggat cttgtgatctaa |
Protein Sequence |
>6678 : length: 303 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKD LVI |