Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6678

Name

SPARC

Synonymous

ON;secreted protein, acidic, cysteine-rich (osteonectin);SPARC;secreted protein, acidic, cysteine-rich (osteonectin)

Definition

BM-40|basement-membrane protein 40|cysteine-rich protein|osteonectin|secreted protein acidic and rich in cysteine

Position

5q31.3-q32

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

SPARC(h) --> osteonectin(h) (expression).
SPARC(h) --> osteonectin(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

116N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

 Promoter: 151046210 - 151048210GoldenGate_Methylation_Cancer_Panel_I

chr5

 Promoter: 151046210 - 151048210GSE27584

chr5

 Promoter: 151046210 - 151048210PMID:12902985

chr5

 Promoter: 151046210 - 151048210PMID:16424060

chr5

 Promoter: 151046210 - 151048210PMID:16598760

')