| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7128 |
Name | TNFAIP3 |
Synonym | A20|OTUD7C|TNFA1P2;tumor necrosis factor, alpha-induced protein 3;TNFAIP3;tumor necrosis factor, alpha-induced protein 3 |
Definition | OTU domain-containing protein 7C|TNF alpha-induced protein 3|putative DNA-binding protein A20|tumor necrosis factor alpha-induced protein 3|tumor necrosis factor inducible protein A20|zinc finger protein A20 |
Position | 6q23 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 16831 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | TNF receptor signaling pathway;PID Curated;200086 |
Pathway | NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621 |
Pathway | cd40l signaling pathway;PID BioCarta;100213 |
Pathway | CD40/CD40L signaling;PID Curated;200031 |
Pathway | Canonical NF-kappaB pathway;PID Curated;200026 |
Pathway | Toll receptor signaling pathway;PANTHER;P00054 |
Pathway | tnfr2 signaling pathway;PID BioCarta;100014 |
Disease | IMMUNE;GAD |
Disease | Wegener's granulomatosis;GAD |
Disease | Celiac disease;NHGRI |
Disease | atherosclerosis, coronary;GAD |
Disease | Celiac Disease;GAD |
Disease | Psoriasis;NHGRI |
Disease | CARDIOVASCULAR;GAD |
Disease | psoriasis;GAD |
Disease | Rheumatoid arthritis;NHGRI |
Disease | Systemic lupus erythematosus;NHGRI |
Disease | rheumatoid arthritis;GAD |
Disease | systemic lupus erythematosus;GAD |
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External Links |
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Links to Entrez Gene | 7128 |
Links to all GeneRIF Items | 7128 |
Links to iHOP | 7128 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7128 : length: 2373 atggctgaacaagtccttcctcaggctttgtatttgagcaatatgcggaaagctgtgaag atacgggagagaactccagaagacatttttaaacctactaatgggatcattcatcatttt aaaaccatgcaccgatacacactggaaatgttcagaacttgccagttttgtcctcagttt cgggagatcatccacaaagccctcatcgacagaaacatccaggccaccctggaaagccag aagaaactcaactggtgtcgagaagtccggaagcttgtggcgctgaaaacgaacggtgac ggcaattgcctcatgcatgccacttctcagtacatgtggggcgttcaggacacagacttg gtactgaggaaggcgctgttcagcacgctcaaggaaacagacacacgcaactttaaattc cgctggcaactggagtctctcaaatctcaggaatttgttgaaacggggctttgctatgat actcggaactggaatgatgaatgggacaatcttatcaaaatggcttccacagacacaccc atggcccgaagtggacttcagtacaactcactggaagaaatacacatatttgtcctttgc aacatcctcagaaggccaatcattgtcatttcagacaaaatgctaagaagtttggaatca ggttccaatttcgcccctttgaaagtgggtggaatttacttgcctctccactggcctgcc caggaatgctacagataccccattgttctcggctatgacagccatcattttgtacccttg gtgaccctgaaggacagtgggcctgaaatccgagctgttccacttgttaacagagaccgg ggaagatttgaagacttaaaagttcactttttgacagatcctgaaaatgagatgaaggag aagctcttaaaagagtacttaatggtgatagaaatccccgtccaaggctgggaccatggc acaactcatctcatcaatgccgcaaagttggatgaagctaacttaccaaaagaaatcaat ctggtagatgattactttgaacttgttcagcatgagtacaagaaatggcaggaaaacagc gagcaggggaggagagaggggcacgcccagaatcccatggaaccttccgtgccccagctt tctctcatggatgtaaaatgtgaaacgcccaactgccccttcttcatgtctgtgaacacc cagcctttatgccatgagtgctcagagaggcggcaaaagaatcaaaacaaactcccaaag ctgaactccaagccgggccctgaggggctccctggcatggcgctcggggcctctcgggga gaagcctatgagcccttggcgtggaaccctgaggagtccactggggggcctcattcggcc ccaccgacagcacccagcccttttctgttcagtgagaccactgccatgaagtgcaggagc cccggctgccccttcacactgaatgtgcagcacaacggattttgtgaacgttgccacaac gcccggcaacttcacgccagccacgccccagaccacacaaggcacttggatcccgggaag tgccaagcctgcctccaggatgttaccaggacatttaatgggatctgcagtacttgcttc aaaaggactacagcagaggcctcctccagcctcagcaccagcctccctccttcctgtcac cagcgttccaagtcagatccctcgcggctcgtccggagcccctccccgcattcttgccac agagctggaaacgacgcccctgctggctgcctgtctcaagctgcacggactcctggggac aggacggggacgagcaagtgcagaaaagccggctgcgtgtattttgggactccagaaaac aagggcttttgcacactgtgtttcatcgagtacagagaaaacaaacattttgctgctgcc tcagggaaagtcagtcccacagcgtccaggttccagaacaccattccgtgcctggggagg gaatgcggcacccttggaagcaccatgtttgaaggatactgccagaagtgtttcattgaa gctcagaatcagagatttcatgaggccaaaaggacagaagagcaactgagatcgagccag cgcagagatgtgcctcgaaccacacaaagcacctcaaggcccaagtgcgcccgggcctcc tgcaagaacatcctggcctgccgcagcgaggagctctgcatggagtgtcagcatcccaac cagaggatgggccctggggcccaccggggtgagcctgcccccgaagacccccccaagcag cgttgccgggcccccgcctgtgatcattttggcaatgccaagtgcaacggctactgcaac gaatgctttcagttcaagcagatgtatggctaa |
Protein Sequence |
>7128 : length: 790 MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQF REIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDL VLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTP MARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPA QECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKE KLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENS EQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPK LNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRS PGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCF KRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGD RTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGR ECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARAS CKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCN ECFQFKQMYG |