Entrez Gene

Basic Information
Gene ID	7128
Name	TNFAIP3
Synonymous	tumor necrosis factor, alpha-induced protein 3;TNFAIP3;tumor necrosis factor, alpha-induced protein 3
Definition	OTU domain-containing protein 7C\|TNF alpha-induced protein 3\|putative DNA-binding protein A20\|tumor necrosis factor alpha-induced protein 3\|tumor necrosis factor inducible protein A20\|zinc finger protein A20
Position	6q23
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.62.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1696G>T; p.D566Y; 6:137879141-137879141	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1228_1229delAG; p.R410fs*18; 6:137878673-137878674	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.591T>C; p.F197F; 6:137875792-137875792	skin	malignant_melanoma	Substitution - coding silent
c.1977G>T; p.G659G; 6:137880141-137880141	breast	carcinoma	Substitution - coding silent
c.400_401delGA; p.D134fs*5; 6:137874949-137874950	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.1100G>T; p.G367V; 6:137878545-137878545	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1123C>T; p.P375S; 6:137878568-137878568	liver	carcinoma	Substitution - Missense
c.1354G>T; p.E452*; 6:137878799-137878799	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.205_206insCCTC; p.I69fs*33; 6:137871432-137871433	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.840G>A; p.R280R; 6:137877110-137877110	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1354G>T; p.E452*; 6:137878799-137878799	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Nonsense
c.1725C>T; p.S575S; 6:137879170-137879170	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1084C>T; p.Q362*; 6:137878529-137878529	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1084C>T; p.Q362*; 6:137878529-137878529	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.295+2T>G; p.?; 6:137871524-137871524	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.436_437delTC; p.L147fs*7; 6:137874985-137874986	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.262G>T; p.E88*; 6:137871489-137871489	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; AIDS_related_lymphoma	Substitution - Nonsense
c.2341G>A; p.E781K; 6:137881287-137881287	skin	malignant_melanoma	Substitution - Missense
c.2341G>A; p.E781K; 6:137881287-137881287	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1101G>A; p.G367G; 6:137878546-137878546	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - coding silent
c.1876_1877delCT; p.L626fs*45; 6:137879321-137879322	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.491G>A; p.W164*; 6:137875692-137875692	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.253T>A; p.W85R; 6:137871480-137871480	liver	carcinoma	Substitution - Missense
c.253T>A; p.W85R; 6:137871480-137871480	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.253T>A; p.W85R; 6:137871480-137871480	liver	carcinoma	Substitution - Missense
c.735_741delATACCCC; p.Y246fs*14; 6:137876096-137876102	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.254G>C; p.W85S; 6:137871481-137871481	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1367G>T; p.G456V; 6:137878812-137878812	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Missense
c.1263G>A; p.L421L; 6:137878708-137878708	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.666C>T; p.S222S; 6:137876027-137876027	skin	malignant_melanoma	Substitution - coding silent
c.1476C>T; p.N492N; 6:137878921-137878921	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1347_1423del77; p.P450fs*21; 6:137878792-137878868	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1004T>G; p.L335*; 6:137878449-137878449	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1763C>G; p.A588G; 6:137879208-137879208	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1004T>G; p.L335*; 6:137878449-137878449	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1763C>G; p.A588G; 6:137879208-137879208	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.360_361insCTTG; p.V121fs*20; 6:137874909-137874910	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.750C>T; p.L250L; 6:137876111-137876111	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.58A>C; p.K20Q; 6:137871285-137871285	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2251G>A; p.E751K; 6:137881197-137881197	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.1967C>T; p.P656L; 6:137880131-137880131	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1090A>G; p.R364G; 6:137878535-137878535	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.705T>C; p.P235P; 6:137876066-137876066	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.705T>C; p.P235P; 6:137876066-137876066	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.615G>T; p.R205S; 6:137875816-137875816	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.295+1G>T; p.?; 6:137871523-137871523	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.295+1G>T; p.?; 6:137871523-137871523	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.91A>T; p.K31*; 6:137871318-137871318	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; AIDS_related_lymphoma	Substitution - Nonsense
c.2252A>G; p.E751G; 6:137881198-137881198	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.407G>A; p.R136H; 6:137874956-137874956	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1898_1899delAA; p.N634fs*37; 6:137879343-137879344	haematopoietic_and_lymphoid_tissue; small_intestine	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.407G>A; p.R136H; 6:137874956-137874956	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1130T>C; p.V377A; 6:137878575-137878575	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1368G>A; p.G456G; 6:137878813-137878813	thyroid	other; neoplasm	Substitution - coding silent
c.407G>A; p.R136H; 6:137874956-137874956	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.350A>G; p.D117G; 6:137874899-137874899	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1965T>A; p.I655I; 6:137880129-137880129	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.350A>G; p.D117G; 6:137874899-137874899	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.350A>G; p.D117G; 6:137874899-137874899	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.54T>C; p.A18A; 6:137871281-137871281	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.709C>T; p.H237Y; 6:137876070-137876070	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2120_2121CC>TT; p.T707I; 6:137881066-137881067	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1005A>G; p.L335L; 6:137878450-137878450	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1091G>A; p.R364K; 6:137878536-137878536	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2238_2239delGG; p.A747fs*4; 6:137881184-137881185	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.149_155delTGTTCAG; p.M50fs*44; 6:137871376-137871382	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.1341G>T; p.A447A; 6:137878786-137878786	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1758_1809del52; p.P587fs*93; 6:137879203-137879254	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.1712T>C; p.V571A; 6:137879157-137879157	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.733_733delA; p.R245fs*17; 6:137876094-137876094	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.322A>G; p.T108A; 6:137874871-137874871	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.189C>T; p.I63I; 6:137871416-137871416	skin	malignant_melanoma	Substitution - coding silent
c.748_763del16; p.L250fs*7; 6:137876109-137876124	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.2343A>G; p.E781E; 6:137881289-137881289	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.568T>C; p.S190P; 6:137875769-137875769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1232G>A; p.R411Q; 6:137878677-137878677	central_nervous_system; brain	glioma	Substitution - Missense
c.2198G>T; p.C733F; 6:137881144-137881144	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.503G>A; p.W168*; 6:137875704-137875704	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Nonsense
c.825_825delT; p.V276fs*11; 6:137877095-137877095	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.1524C>T; p.H508H; 6:137878969-137878969	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1335C>T; p.P445P; 6:137878780-137878780	skin	malignant_melanoma	Substitution - coding silent
c.548G>A; p.R183Q; 6:137875749-137875749	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.274delC; p.V93fs*3; 6:137871501-137871501	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.296-35_296-2del34; p.?; 6:137874810-137874843	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Unknown
c.704_705delCT; p.L236fs*17; 6:137876065-137876066	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.1786C>T; p.R596W; 6:137879231-137879231	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.484_485insG; p.N163fs*4; 6:137875033-137875034	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.1274C>T; p.P425L; 6:137878719-137878719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1269_1270insC; p.K424fs*5; 6:137878714-137878715	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.788_789insG; p.K264fs*6; 6:137876149-137876150	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.1444G>A; p.G482S; 6:137878889-137878889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1711G>A; p.V571I; 6:137879156-137879156	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.1944G>A; p.A648A; 6:137880108-137880108	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1710C>T; p.L570L; 6:137879155-137879155	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1710C>T; p.L570L; 6:137879155-137879155	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.487-6C>A; p.?; 6:137875682-137875682	pancreas	carcinoma	Unknown
c.423C>A; p.R141R; 6:137874972-137874972	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.222G>T; p.Q74H; 6:137871449-137871449	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.745_751delGTTCTCG; p.V249fs*11; 6:137876106-137876112	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.2149G>T; p.A717S; 6:137881095-137881095	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.733A>T; p.R245*; 6:137876094-137876094	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.2290_2290delG; p.A764fs*28; 6:137881236-137881236	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1400C>A; p.P467H; 6:137878845-137878845	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.244A>T; p.K82*; 6:137871471-137871471	haematopoietic_and_lymphoid_tissue; abdomen	lymphoid_neoplasm; follicular_lymphoma	Substitution - Nonsense
c.1244_1248delAAAAC; p.N416fs*11; 6:137878689-137878693	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.995A>G; p.E332G; 6:137878440-137878440	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.559C>T; p.Q187*; 6:137875760-137875760	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.559C>T; p.Q187*; 6:137875760-137875760	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1627A>G; p.T543A; 6:137879072-137879072	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2335T>C; p.C779R; 6:137881281-137881281	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.2254C>T; p.P752S; 6:137881200-137881200	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Missense
c.485delG; p.N163fs*53; 6:137875034-137875034	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.294_295+4delCGGTAA; p.?; 6:137871521-137871526	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.835_836delGA; p.D279fs*5; 6:137877105-137877106	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.518A>C; p.K173T; 6:137875719-137875719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1681C>T; p.Q561*; 6:137879126-137879126	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Nonsense
c.2273C>G; p.P758R; 6:137881219-137881219	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.835_836delGA; p.D279fs*5; 6:137877105-137877106	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.2368G>T; p.G790C; 6:137881314-137881314	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.337_420del84; p.W113_F140del; 6:137874886-137874969	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - In frame
c.989_989delT; p.L330fs*13; 6:137878434-137878434	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.761G>A; p.S254N; 6:137876122-137876122	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1370delC; p.P457fs*20; 6:137878815-137878815	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.1982A>G; p.E661G; 6:137880146-137880146	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.761G>T; p.S254I; 6:137876122-137876122	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.761G>T; p.S254I; 6:137876122-137876122	stomach	adenocarcinoma	Substitution - Missense
c.1893_1906+7del21; p.?; 6:137879338-137879358	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.399_400delAG; p.D134fs*5; 6:137874948-137874949	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.181C>T; p.R61W; 6:137871408-137871408	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1876C>A; p.L626M; 6:137879321-137879321	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.399_400delAG; p.D134fs*5; 6:137874948-137874949	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.359T>G; p.L120W; 6:137874908-137874908	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Missense
c.127_134delATGCACCG; p.M43fs*55; 6:137871354-137871361	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.2274_2274delC; p.K759fs*33; 6:137881220-137881220	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1162G>T; p.E388*; 6:137878607-137878607	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1728G>A; p.P576P; 6:137879173-137879173	breast	carcinoma	Substitution - coding silent
c.1728G>A; p.P576P; 6:137879173-137879173	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1385C>A; p.P462Q; 6:137878830-137878830	skin	malignant_melanoma	Substitution - Missense
c.1420A>G; p.T474A; 6:137878865-137878865	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.813A>G; p.R271R; 6:137877083-137877083	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1260_1260delG; p.K420fs*2; 6:137878705-137878705	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1517_1536del20; p.A506fs*21; 6:137878962-137878981	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.65G>A; p.R22Q; 6:137871292-137871292	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.813A>G; p.R271R; 6:137877083-137877083	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1507C>T; p.Q503*; 6:137878952-137878952	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1507C>T; p.Q503*; 6:137878952-137878952	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1968G>A; p.P656P; 6:137880132-137880132	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1507C>T; p.Q503*; 6:137878952-137878952	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.423C>T; p.R141R; 6:137874972-137874972	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.425G>A; p.W142*; 6:137874974-137874974	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.425G>A; p.W142*; 6:137874974-137874974	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Nonsense
c.295+1G>A; p.?; 6:137871523-137871523	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.380T>G; p.F127C; 6:137874929-137874929	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Missense
c.380T>G; p.F127C; 6:137874929-137874929	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1362_1363insG; p.P457fs*16; 6:137878807-137878808	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2214_2215insT; p.P739fs*13; 6:137881160-137881161	haematopoietic_and_lymphoid_tissue; lung	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.1067G>A; p.W356*; 6:137878512-137878512	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.380T>G; p.F127C; 6:137874929-137874929	thyroid	other; neoplasm	Substitution - Missense
c.1368_1369insG; p.P457fs*16; 6:137878813-137878814	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.1494C>A; p.C498*; 6:137878939-137878939	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1309_1309delG; p.A437fs*40; 6:137878754-137878754	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.322_323insA; p.T108fs*32; 6:137874871-137874872	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.2274_2275insCC; p.K759fs*34; 6:137881220-137881221	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Insertion - Frameshift
c.162C>A; p.C54*; 6:137871389-137871389	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.295G>T; p.G99C; 6:137871522-137871522	thyroid	other; neoplasm	Substitution - Missense
c.382_382delA; p.S128fs*88; 6:137874931-137874931	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.1984_1988TGCGG>TTGCCGT; p.C662fs*36; 6:137880148-137880152	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Complex - frameshift
c.1421C>A; p.T474N; 6:137878866-137878866	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.593T>C; p.V198A; 6:137875794-137875794	breast	other; fibroadenoma	Substitution - Missense
c.2102G>A; p.R701H; 6:137881048-137881048	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.282G>C; p.A94A; 6:137871509-137871509	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2342A>G; p.E781G; 6:137881288-137881288	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1368_1368delG; p.P457fs*20; 6:137878813-137878813	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.1871G>A; p.C624Y; 6:137879316-137879316	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.922A>G; p.M308V; 6:137877192-137877192	bone; femur	chondrosarcoma	Substitution - Missense
c.2315A>G; p.N772S; 6:137881261-137881261	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.441C>G; p.L147L; 6:137874990-137874990	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1376C>G; p.S459W; 6:137878821-137878821	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.905T>C; p.L302P; 6:137877175-137877175	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.987-2A>G; p.?; 6:137878430-137878430	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.520_521delAT; p.M174fs*79; 6:137875721-137875722	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.905T>C; p.L302P; 6:137877175-137877175	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.52G>C; p.A18P; 6:137871279-137871279	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2291C>T; p.A764V; 6:137881237-137881237	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1316G>T; p.R439L; 6:137878761-137878761	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.7G>T; p.E3*; 6:137871234-137871234	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.295_295+4delGGTAA; p.?; 6:137871522-137871522	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Unknown
c.1363delG; p.P457fs*20; 6:137878808-137878808	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.1363delG; p.P457fs*20; 6:137878808-137878808	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1246_1250delAACAA; p.N416fs*11; 6:137878691-137878695	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.650G>C; p.S217T; 6:137876011-137876011	breast	carcinoma	Substitution - Missense
c.1879_1880delTG; p.C627fs*44; 6:137879324-137879325	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.838_848del11; p.R280fs*1; 6:137877108-137877118	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.463A>G; p.T155A; 6:137875012-137875012	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.268C>T; p.R90W; 6:137871495-137871495	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.463A>G; p.T155A; 6:137875012-137875012	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.294_295insA; p.G99fs*2; 6:137871521-137871522	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.1092_1093delGA; p.E366fs*22; 6:137878537-137878538	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.553G>T; p.G185*; 6:137875754-137875754	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Nonsense
c.294_295insA; p.G99fs*2; 6:137871521-137871522	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.465G>A; p.T155T; 6:137875014-137875014	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.465G>A; p.T155T; 6:137875014-137875014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2267_2268insC; p.K759fs*10; 6:137881213-137881214	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.465G>A; p.T155T; 6:137875014-137875014	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.241_241delA; p.K81fs*15; 6:137871468-137871468	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.926_927insT; p.I310fs*23; 6:137877196-137877197	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Insertion - Frameshift
c.208G>A; p.D70N; 6:137871435-137871435	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.130_137delCACCGATA; p.R45fs*53; 6:137871357-137871364	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1756G>A; p.A586T; 6:137879201-137879201	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; AIDS_related_lymphoma	Substitution - Missense
c.735A>T; p.R245S; 6:137876096-137876096	lung	carcinoid-endocrine_tumour; atypical	Substitution - Missense
c.1065A>G; p.K355K; 6:137878510-137878510	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.350A>T; p.D117V; 6:137874899-137874899	haematopoietic_and_lymphoid_tissue; large_intestine	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1841A>G; p.Y614C; 6:137879286-137879286	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1714C>A; p.R572R; 6:137879159-137879159	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1412G>C; p.S471T; 6:137878857-137878857	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1261C>G; p.L421V; 6:137878706-137878706	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1295_1296delGC; p.G432fs*12; 6:137878740-137878741	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.1306G>A; p.G436R; 6:137878751-137878751	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.672C>T; p.F224F; 6:137876033-137876033	breast	carcinoma	Substitution - coding silent
c.829_830insTGTT; p.N277fs*9; 6:137877099-137877100	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.1167G>A; p.T389T; 6:137878612-137878612	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1514_1515insA; p.H505fs*29; 6:137878959-137878960	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.1167G>A; p.T389T; 6:137878612-137878612	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2175G>A; p.L725L; 6:137881121-137881121	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.1292C>T; p.P431L; 6:137878737-137878737	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1341G>A; p.A447A; 6:137878786-137878786	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.853G>A; p.D285N; 6:137877123-137877123	urinary_tract; bladder	carcinoma	Substitution - Missense
c.638_639insG; p.M214fs*40; 6:137875999-137876000	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.1343G>A; p.W448*; 6:137878788-137878788	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Nonsense
c.305A>G; p.N102S; 6:137874854-137874854	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.305A>G; p.N102S; 6:137874854-137874854	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.301G>A; p.G101S; 6:137874850-137874850	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.305A>G; p.N102S; 6:137874854-137874854	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.305A>G; p.N102S; 6:137874854-137874854	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.305A>G; p.N102S; 6:137874854-137874854	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1986C>T; p.C662C; 6:137880150-137880150	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2342A>C; p.E781A; 6:137881288-137881288	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1986C>T; p.C662C; 6:137880150-137880150	central_nervous_system; brain	glioma	Substitution - coding silent
c.1986C>T; p.C662C; 6:137880150-137880150	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1526C>T; p.A509V; 6:137878971-137878971	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.996A>G; p.E332E; 6:137878441-137878441	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.996A>G; p.E332E; 6:137878441-137878441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.301_303GGC>A; p.G101fs*38; 6:137874850-137874852	haematopoietic_and_lymphoid_tissue; skin	lymphoid_neoplasm; marginal_zone_lymphoma	Complex - frameshift
c.996A>G; p.E332E; 6:137878441-137878441	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.996A>G; p.E332E; 6:137878441-137878441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.987G>A; p.K329K; 6:137878432-137878432	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - coding silent
c.950G>A; p.W317*; 6:137877220-137877220	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.255G>A; p.W85*; 6:137871482-137871482	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.2161delT; p.C721fs*71; 6:137881107-137881107	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.637A>C; p.K213Q; 6:137875998-137875998	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.328C>T; p.Q110*; 6:137874877-137874877	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Nonsense
c.2266_2267insC; p.D756fs*13; 6:137881212-137881213	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.1468C>T; p.Q490*; 6:137878913-137878913	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.295+43T>G; p.?; 6:137871565-137871565	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.257_257delG; p.C86fs*10; 6:137871484-137871484	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.491_492insA; p.W164fs*1; 6:137875692-137875693	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.1500C>T; p.N500N; 6:137878945-137878945	breast	carcinoma	Substitution - coding silent
c.1468C>T; p.Q490*; 6:137878913-137878913	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.290_291insA; p.N98fs*3; 6:137871517-137871518	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.295+43T>G; p.?; 6:137871565-137871565	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.1468C>T; p.Q490*; 6:137878913-137878913	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1135C>T; p.Q379*; 6:137878580-137878580	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Nonsense
c.1366G>C; p.G456R; 6:137878811-137878811	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.262_263insA; p.V89fs*12; 6:137871489-137871490	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.1777C>T; p.Q593*; 6:137879222-137879222	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1864G>T; p.G622C; 6:137879309-137879309	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1777C>T; p.Q593*; 6:137879222-137879222	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1877_1878delTG; p.C627fs*44; 6:137879322-137879323	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.1877_1878delTG; p.C627fs*44; 6:137879322-137879323	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.771_772insTT; p.V258fs*5; 6:137876132-137876133	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.1485T>A; p.C495*; 6:137878930-137878930	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.2274_2275insC; p.K759fs*10; 6:137881220-137881221	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.1428G>A; p.M476I; 6:137878873-137878873	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2209C>T; p.Q737*; 6:137881155-137881155	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Nonsense
c.362_363ins136; p.Q150fs*35; 6:137874911-137874912	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.397_398insA; p.T133fs*7; 6:137874946-137874947	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.1983A>G; p.E661E; 6:137880147-137880147	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1129G>A; p.V377M; 6:137878574-137878574	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1282G>T; p.E428*; 6:137878727-137878727	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.133C>T; p.R45*; 6:137871360-137871360	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.460G>T; p.E154*; 6:137875009-137875009	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.979G>T; p.A327S; 6:137877249-137877249	breast	carcinoma	Substitution - Missense
c.548G>T; p.R183L; 6:137875749-137875749	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.994G>T; p.E332*; 6:137878439-137878439	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.2034C>A; p.F678L; 6:137880198-137880198	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.569C>T; p.S190L; 6:137875770-137875770	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.487-4T>C; p.?; 6:137875684-137875684	liver	carcinoma	Unknown
c.866_867delAC; p.H289fs*6; 6:137877136-137877137	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.1529_1530insC; p.D511fs*23; 6:137878974-137878975	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.866_867delAC; p.H289fs*6; 6:137877136-137877137	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.388C>A; p.L130I; 6:137874937-137874937	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2109_2110delTG; p.V704fs*47; 6:137881055-137881056	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Deletion - Frameshift
c.2209C>A; p.Q737K; 6:137881155-137881155	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.391A>C; p.K131Q; 6:137874940-137874940	prostate	carcinoma	Substitution - Missense
c.920T>A; p.L307*; 6:137877190-137877190	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1817_1818insGTAAA; p.C607fs*1; 6:137879262-137879263	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.353_354delCA; p.T118fs*21; 6:137874902-137874903	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.405_406delAC; p.R136fs*3; 6:137874954-137874955	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.405_406delAC; p.R136fs*3; 6:137874954-137874955	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.2257G>A; p.A753T; 6:137881203-137881203	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Missense
c.812G>T; p.R271L; 6:137877082-137877082	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1721C>T; p.P574L; 6:137879166-137879166	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1721C>T; p.P574L; 6:137879166-137879166	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1932C>T; p.V644V; 6:137880096-137880096	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.987-53_1048del115; p.?; 6:137878379-137878493	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; MALT_lymphoma	Unknown
c.872_873insT; p.L291fs*5; 6:137877142-137877143	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.36G>C; p.L12F; 6:137871263-137871263	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1880G>A; p.C627Y; 6:137879325-137879325	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1942G>T; p.A648S; 6:137880106-137880106	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1942G>T; p.A648S; 6:137880106-137880106	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.406_407insA; p.R136fs*4; 6:137874955-137874956	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.295+1_295+5delGTAAG; p.?; 6:137871523-137871527	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.1897G>A; p.E633K; 6:137879342-137879342	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2329G>T; p.G777C; 6:137881275-137881275	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.285_286insA; p.T97fs*4; 6:137871512-137871513	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.2116C>T; p.R706*; 6:137881062-137881062	skin	malignant_melanoma	Substitution - Nonsense
c.2343A>T; p.E781D; 6:137881289-137881289	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1106C>T; p.A369V; 6:137878551-137878551	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.549_550ins29; p.S184fs*42; 6:137875750-137875751	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Hodgkin_lymphoma	Insertion - Frameshift
c.549_550ins29; p.S184fs*42; 6:137875750-137875751	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Insertion - Frameshift
c.1475_1476insA; p.N492fs*5; 6:137878920-137878921	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.251_251delA; p.N84fs*12; 6:137871478-137871478	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.406C>T; p.R136C; 6:137874955-137874955	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2327A>G; p.N776S; 6:137881273-137881273	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.406C>T; p.R136C; 6:137874955-137874955	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.505G>A; p.D169N; 6:137875706-137875706	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.406C>T; p.R136C; 6:137874955-137874955	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.2327A>G; p.N776S; 6:137881273-137881273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2089-2_2089-1del2; p.?; 6:137881033-137881034	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Unknown
c.2327A>G; p.N776S; 6:137881273-137881273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.296-1G>A; p.?; 6:137874844-137874844	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; MALT_lymphoma	Unknown
c.2316T>G; p.N772K; 6:137881262-137881262	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.872_872delT; p.L291fs*1; 6:137877142-137877142	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.254G>A; p.W85*; 6:137871481-137871481	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Substitution - Nonsense
c.106_107ins10; p.?fs; 6:137871333-137871334	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Insertion - Frameshift
c.66_67delGG; p.R24fs*7; 6:137871293-137871294	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Deletion - Frameshift
c.1355A>G; p.E452G; 6:137878800-137878800	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.161G>A; p.C54Y; 6:137871388-137871388	liver	carcinoma	Substitution - Missense
c.506A>TT; p.D169fs*85; 6:137875707-137875707	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Complex - frameshift
c.1880_1881delGT; p.C627fs*44; 6:137879325-137879326	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1532_1533insC; p.H512fs*22; 6:137878977-137878978	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Insertion - Frameshift
c.464C>T; p.T155M; 6:137875013-137875013	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1376C>T; p.S459L; 6:137878821-137878821	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1943C>T; p.A648V; 6:137880107-137880107	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2333A>G; p.Y778C; 6:137881279-137881279	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.569C>A; p.S190*; 6:137875770-137875770	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1243C>A; p.Q415K; 6:137878688-137878688	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1310_1319del10; p.A437fs*37; 6:137878755-137878764	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; AIDS_related_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lung	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; Hodgkin_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1080C>T; p.S360S; 6:137878525-137878525	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Whole gene deletion
c.1_2373del2373; p.0?; 6:137871228-137881319	haematopoietic_and_lymphoid_tissue; lung	lymphoid_neoplasm; marginal_zone_lymphoma	Whole gene deletion
c.1831G>A; p.G611S; 6:137879276-137879276	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.259C>T; p.R87*; 6:137871486-137871486	breast	carcinoma	Substitution - Nonsense
c.307T>G; p.C103G; 6:137874856-137874856	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1066T>C; p.W356R; 6:137878511-137878511	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.93A>G; p.K31K; 6:137871320-137871320	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.373_382del10; p.L126fs*87; 6:137874922-137874931	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.93A>G; p.K31K; 6:137871320-137871320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.93A>G; p.K31K; 6:137871320-137871320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1685G>A; p.R562H; 6:137879130-137879130	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.465G>T; p.T155T; 6:137875014-137875014	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.268_268delC; p.R90fs*6; 6:137871495-137871495	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.465G>T; p.T155T; 6:137875014-137875014	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1423G>A; p.A475T; 6:137878868-137878868	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.861_861delA; p.V288fs*4; 6:137877131-137877131	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.1685G>A; p.R562H; 6:137879130-137879130	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1981G>T; p.E661*; 6:137880145-137880145	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.972C>T; p.L324L; 6:137877242-137877242	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1376C>A; p.S459*; 6:137878821-137878821	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.673G>A; p.A225T; 6:137876034-137876034	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2277G>T; p.K759N; 6:137881223-137881223	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.510_511insA; p.L171fs*83; 6:137875711-137875712	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.510_511insA; p.L171fs*83; 6:137875711-137875712	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Insertion - Frameshift
c.740C>A; p.P247H; 6:137876101-137876101	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1806delG; p.T604fs*93; 6:137879251-137879251	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.971_975delTCATC; p.L324fs*7; 6:137877241-137877245	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Deletion - Frameshift
c.971_975delTCATC; p.L324fs*7; 6:137877241-137877245	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.971_975delTCATC; p.L324fs*7; 6:137877241-137877245	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - Frameshift
c.971_975delTCATC; p.L324fs*7; 6:137877241-137877245	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.971_975delTCATC; p.L324fs*7; 6:137877241-137877245	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.282_286delGCTGA; p.L95fs*4; 6:137871509-137871513	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.2371_2373TAA>CAG; p.*791Q; 6:137881317-137881319	haematopoietic_and_lymphoid_tissue; mediastinum	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Nonstop extension
c.295+2_295+6del TAAGA; p.?; 6:137871524-137871528	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Unknown
c.581T>C; p.I194T; 6:137875782-137875782	haematopoietic_and_lymphoid_tissue; ocular_adnexa	lymphoid_neoplasm; MALT_lymphoma	Substitution - Missense
c.2328C>T; p.N776N; 6:137881274-137881274	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.627C>G; p.V209V; 6:137875828-137875828	breast	carcinoma	Substitution - coding silent
c.45G>T; p.M15I; 6:137871272-137871272	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1077C>A; p.N359K; 6:137878522-137878522	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.703C>A; p.P235T; 6:137876064-137876064	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1875_1876delAC; p.L626fs*45; 6:137879320-137879321	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.811C>T; p.R271*; 6:137877081-137877081	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.811C>T; p.R271*; 6:137877081-137877081	haematopoietic_and_lymphoid_tissue; stomach	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.811C>T; p.R271*; 6:137877081-137877081	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.811C>T; p.R271*; 6:137877081-137877081	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Substitution - Nonsense
c.1867delT; p.C624fs*73; 6:137879312-137879312	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.336_354del19; p.W113fs*4; 6:137874885-137874903	haematopoietic_and_lymphoid_tissue; eye	lymphoid_neoplasm; MALT_lymphoma	Deletion - Frameshift
c.635A>G; p.D212G; 6:137875996-137875996	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.R183*; 6:137875748-137875748	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.547C>T; p.R183*; 6:137875748-137875748	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.547C>T; p.R183*; 6:137875748-137875748	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]