| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7158 |
Name | TP53BP1 |
Synonym | 53BP1|p202|p53BP1;tumor protein p53 binding protein 1;TP53BP1;tumor protein p53 binding protein 1 |
Definition | p53-binding protein 1|tumor protein 53-binding protein, 1|tumor protein p53-binding protein, 1|tumor suppressor p53-binding protein 1 |
Position | 15q15-q21 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 109 |
TUSON P-value | 2.53E-05 |
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Pathways and Diseases |
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Pathway | Recruitment of repair and signaling proteins to double-strand breaks;PID Reactome;500044 |
Pathway | DNA Repair;Reactome;REACT:216 |
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External Links |
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Links to Entrez Gene | 7158 |
Links to all GeneRIF Items | 7158 |
Links to iHOP | 7158 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7158 : length: 5928 atgcctggggagcagatggaccctactggaagtcagttggattcagatttctctcagcaa gatactccttgcctgataattgaagattctcagcctgaaagccaggttctagaggatgat tctggttctcacttcagtatgctatctcgacaccttcctaatctccagacgcacaaagaa aatcctgtgttggatgttgtgtccaatcctgaacaaacagctggagaagaacgaggagac ggtaatagtgggttcaatgaacatttgaaagaaaacaaggttgcagaccctgtggattct tctaacttggacacatgtggttccatcagtcaggtcattgagcagttacctcagccaaac aggacaagcagtgttctgggaatgtcagtggaatctgctcctgctgtggaggaagagaag ggagaagagttggaacagaaggagaaagagaaggaagaagatacttcaggcaatactaca cattcccttggtgctgaagatactgcctcatcacagttgggttttggggttctggaactc tcccagagccaggatgttgaggaaaatactgtgccatatgaagtggacaaagagcagcta caatcagtaaccaccaactctggttataccaggctgtctgatgtggatgctaatactgca attaagcatgaagaacagtccaacgaagatatccccatagcagaacagtccagcaaggac atccctgtgacagcacagcccagtaaggatgtacatgttgtaaaagagcaaaatccacca cctgcaaggtcagaggacatgccttttagccccaaagcatctgttgctgctatggaagca aaagaacagttgtctgcacaagaacttatggaaagtggactgcagattcagaagtcacca gagcctgaggttttgtcaactcaggaagacttgtttgaccagagcaataaaacagtatct tctgatggttgctctactccttcaagggaggaaggtgggtgttctttggcttccactcct gccaccactctgcatctcctgcagctctctggtcagaggtcccttgttcaggacagtctt tccacgaattcttcagatcttgttgctccttctcctgatgctttccgatctactcctttt atcgttcctagcagtcccacagagcaagaagggagacaagataagccaatggacacgtca gtgttatctgaagaaggaggagagccttttcagaagaaacttcaaagtggtgaaccagtg gagttagaaaacccccctctcctgcctgagtccactgtatcaccacaagcctcaacacca atatctcagagcacaccagtcttccctcctgggtcacttcctatcccatcccagcctcag ttttctcatgacatttttattccttccccaagtctggaagaacaatcaaatgatgggaag aaagatggagatatgcatagttcatctttgacagttgagtgttctaaaacttcagagatt gaaccaaagaattcccctgaggatcttgggctatctttgacaggggattcttgcaagttg atgctttctacaagtgaatatagtcagtccccaaagatggagagcttgagttctcacaga attgatgaagatggagaaaacacacagattgaggatacggaacccatgtctccagttctc aattctaaatttgttcctgctgaaaatgatagtatcctgatgaatccagcacaggatggt gaagtacaactgagtcagaatgatgacaaaacaaagggagatgatacagacaccagggat gacattagtattttagccactggttgcaagggcagagaagaaacggtagcagaagatgtt tgtattgatctcacttgtgattcggggagtcaggcagttccgtcaccagctactcgatct gaggcactttctagtgtgttagatcaggaggaagctatggaaattaaagaacaccatcca gaggaggggtcttcagggtctgaggtggaagaaatccctgagacaccttgtgaaagtcaa ggagaggaactcaaagaagaaaatatggagagtgttccgttgcacctttctctgactgaa actcagtcccaagggttgtgtcttcaaaaggaaatgccaaaaaaagaatgctcagaagct atggaagttgaaaccagtgtgattagtattgattcccctcaaaagttggcaatacttgac caagaattggaacataaggaacaggaagcttgggaagaagctacttcagaggactccagt gttgtcattgtagatgtgaaagagccatctcccagagttgatgtttcttgtgaacctttg gagggagtggagaagtgctcagattcccagtcatgggaggatattgctccagaaatagaa ccatgtgctgagaatagattagacaccaaggaagaaaagagtgtagaatatgaaggagat ctgaaatcagggactgcagaaacagaacctgtagagcaagattcttcacagccttcctta cctttagtgagagcagatgatcctttaagacttgaccaggagttgcagcagccccaaact caggagaaaacaagtaattcattaacagaagactcaaaaatggctaatgcaaagcagcta agctcagatgcagaggcccagaagctggggaagccctctgcccatgcctcacaaagcttc tgtgaaagttctagtgaaaccccatttcatttcactttgcctaaagaaggtgatatcatc ccaccattgactggtgcaaccccacctcttattgggcacctaaaattggagcccaagaga cacagtactcctattggtattagcaactatccagaaagcaccatagcaaccagtgatgtc atgtctgaaagcatggtggagacccatgatcccatacttgggagtggaaaaggggattct ggggctgccccagacgtggatgataaattatgtctaagaatgaaactggttagtcctgag actgaggcgagtgaagagtctttgcagttcaacctggaaaagcctgcaactggtgaaaga aaaaatggatctactgctgttgctgagtctgttgccagtccccagaagaccatgtctgtg ttgagctgtatctgtgaagccaggcaagagaatgaggctcgaagtgaggatccccccacc acacccatcagggggaacttgctccactttccaagttctcaaggagaagaggagaaagaa aaattggagggtgaccatacaatcaggcagagtcaacagcctatgaagcccattagtcct gtcaaggaccctgtttctcctgcttcccagaagatggtcatacaagggccatccagtcct caaggagaggcaatggtgacagatgtgctagaagaccagaaagaaggacggagtactaat aaggaaaatcctagtaaggccttgattgaaaggcccagccaaaataacataggaatccaa accatggagtgttccttgagggtcccagaaactgtttcagcagcaacccagactataaag aatgtgtgtgagcaggggaccagtacagtggaccagaactttggaaagcaagatgccaca gttcagactgagagggggagtggtgagaaaccagtcagtgctcctggggatgatacagag tcgctccatagccagggagaagaagagtttgatatgcctcagcctccacatggccatgtc ttacatcgtcacatgagaacaatccgggaagtacgcacacttgtcactcgtgtcattaca gatgtgtattatgtggatggaacagaagtagaaagaaaagtaactgaggagactgaagag ccaattgtagagtgtcaggagtgtgaaactgaagtttccccttcacagactgggggctcc tcaggtgacctgggggatatcagctccttctcctccaaggcatccagcttacaccgcaca tcaagtgggacaagtctctcagctatgcacagcagtggaagctcagggaaaggagccgga ccactcagagggaaaaccagcgggacagaacccgcagattttgccttacccagctcccga ggaggcccaggaaaactgagtcctagaaaaggggtcagtcagacagggacgccagtgtgt gaggaggatggtgatgcaggccttggcatcagacagggagggaaggctccagtcacgcct cgtgggcgtgggcgaaggggccgcccaccttctcggaccactggaaccagagaaacagct gtgcctggccccttgggcatagaggacatttcacctaacttgtcaccagatgataaatcc ttcagccgtgtcgtgccccgagtgccagactccaccagacgaacagatgtgggtgctggt gctttgcgtcgtagtgactctccagaaattcctttccaggctgctgctggcccttctgat ggcttagatgcctcctctccaggaaatagctttgtagggctccgtgttgtagccaagtgg tcatccaatggctacttttactctgggaaaatcacacgagatgtcggagctgggaagtat aaattgctctttgatgatgggtacgaatgtgatgtgttgggcaaagacattctgttatgt gaccccatcccgctggacactgaagtgacggccctctcggaggatgagtatttcagtgca ggagtggtgaaaggacataggaaggagtctggggaactgtactacagcattgaaaaagaa ggccaaagaaagtggtataagcgaatggctgtcatcctgtccttggagcaaggaaacaga ctgagagagcagtatgggcttggcccctatgaagcagtaacacctcttacaaaggcagca gatatcagcttagacaatttggtggaagggaagcggaaacggcgcagtaacgtcagctcc ccagccacccctactgcctccagtagcagcagcacaacccctacccgaaagatcacagaa agtcctcgtgcctccatgggagttctctcaggcaaaagaaaacttatcacttctgaagag gaacggtcccctgccaagcgaggtcgcaagtctgccacagtaaaacctgtaggggcagga gagtttgtgagcccctgtgagagtggagacaacaccggtgaaccctctgccctggaagag cagagagggcctttgcctctcaacaagaccttgtttctgggctacgcatttctccttacc atggccacaaccagtgacaagttggccagccgctccaaactgccagatggtcctacagga agcagtgaagaagaggaggaatttttggaaattcctcctttcaacaagcagtatacagaa tcccagcttcgagcaggagctggctatatccttgaagatttcaatgaagcccagtgtaac acagcttaccagtgtcttctaattgcggatcagcattgtcgaacccggaagtacttcctg tgccttgccagtgggattccttgtgtgtctcatgtctgggtccatgatagttgccatgcc aaccagctccagaactaccgtaattatctgttgccagctgggtacagccttgaggagcaa agaattctggactggcaaccccgtgaaaatcctttccagaatctgaaggtactcttggta tcagaccaacagcagaacttcctggagctctggtctgagatcctcatgactggtggtgca gcctctgtgaagcagcaccattcaagtgcccataacaaagatattgctttaggggtattt gatgtggtggtgacggacccctcatgcccagcctcggtgctgaagtgtgctgaagcattg cagctgcctgtggtgtcacaagagtgggtgatccagtgcctcattgttggggagagaatt ggattcaagcagcatccaaaatataaacacgattatgtttctcactaa |
Protein Sequence |
>7158 : length: 1975 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE ERSPAKRGRKSATVKPVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLT MATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCN TAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQ RILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVF DVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH |