General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 7158 |
Name | TP53BP1 |
Synonymous | 53BP1|p202|p53BP1;tumor protein p53 binding protein 1;TP53BP1;tumor protein p53 binding protein 1 |
Definition | p53-binding protein 1|tumor protein 53-binding protein, 1|tumor protein p53-binding protein, 1|tumor suppressor p53-binding protein 1 |
Position | 15q15-q21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ABL1 | IMID; |
in same component |
ATM | NCI_NATURE; |
in same component |
BRCA1 | NCI_NATURE; |
in same component |
BRCA1 | REACTOME; |
in same component |
CREBBP | IMID; |
in same component |
FAM175A | NCI_NATURE; |
in same component |
H2AFX | NCI_NATURE; |
in same component |
H2AFX | REACTOME; |
in same component |
MDC1 | NCI_NATURE; |
in same component |
MDC1 | REACTOME; |
in same component |
MRE11A | NCI_NATURE; |
in same component |
NBN | NCI_NATURE; |
in same component |
RAD50 | NCI_NATURE; |
in same component |
RNF8 | NCI_NATURE; |
in same component |
UIMC1 | NCI_NATURE; |
in same component |
YWHAH | IMID; |
interacts with |
ACACA | INTACT; |
interacts with |
ANAPC1 | INTACT; |
interacts with |
ANAPC4 | INTACT; |
interacts with |
ANAPC5 | INTACT; |
interacts with |
ATM | BIOGRID; |
interacts with |
ATM | HPRD; |
interacts with |
BLM | BIOGRID; |
interacts with |
BLM | HPRD; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
BRCC3 | INTACT; |
interacts with |
CDC16 | INTACT; |
interacts with |
CDC27 | INTACT; |
interacts with |
CHEK1 | BIOGRID; |
interacts with |
CHEK2 | BIOGRID; |
interacts with |
CRB2 | HPRD; |
interacts with |
DCLRE1A | BIOGRID; |
interacts with |
DCLRE1A | HPRD; |
interacts with |
DCLRE1C | HPRD; |
interacts with |
DYNLL1 | BIOGRID; |
interacts with |
DYNLL1 | HPRD; |
interacts with |
E2F1 | BIOGRID; |
interacts with |
E2F1 | HPRD; |
interacts with |
EP300 | HPRD; |
interacts with |
FAM199X | INTACT; |
interacts with |
H2afx | BIOGRID; |
interacts with |
H2AFX | BIOGRID; |
interacts with |
H2AFX | HPRD; |
interacts with |
H2AFX | MINT; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HSPA9 | INTACT; |
interacts with |
IFI16 | HPRD; |
interacts with |
MCPH1 | BIOGRID; |
interacts with |
MDC1 | BIOGRID; |
interacts with |
MDC1 | HPRD; |
interacts with |
NEK1 | HPRD; |
interacts with |
NFKB1 | BIOGRID; |
interacts with |
NFKB1 | HPRD; |
interacts with |
PA1 | INTACT; |
interacts with |
PAXIP1 | BIOGRID; |
interacts with |
PAXIP1 | HPRD; |
interacts with |
Paxip1 | INTACT; |
interacts with |
PAXIP1 | INTACT; |
interacts with |
PAXIP1 | MINT; |
interacts with |
PIAS4 | BIOGRID; |
interacts with |
PLK1 | INTACT; |
interacts with |
RAD18 | BIOGRID; |
interacts with |
Rb1 | BIOGRID; |
interacts with |
RELA | HPRD; |
interacts with |
RNF168 | BIOGRID; |
interacts with |
RNF8 | BIOGRID; |
interacts with |
RPA1 | BIOGRID; |
interacts with |
RPA2 | BIOGRID; |
interacts with |
TFDP1 | BIOGRID; |
interacts with |
TP53I3 | BIOGRID; |
interacts with |
Tp53 | BIOGRID; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TUBA3C | INTACT; |
interacts with |
UBE2I | BIOGRID; |
interacts with |
USP28 | BIOGRID; |
interacts with |
USP28 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for TP53BP1 |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ABL1 | IMID; |
reacts with |
ATM | NCI_NATURE; |
reacts with |
BRCA1 | NCI_NATURE; |
reacts with |
BRCA1 | REACTOME; |
reacts with |
CREBBP | IMID; |
reacts with |
CTBP1 | NCI_NATURE; |
reacts with |
FAM175A | NCI_NATURE; |
reacts with |
H2AFX | NCI_NATURE; |
reacts with |
H2AFX | REACTOME; |
reacts with |
MDC1 | NCI_NATURE; |
reacts with |
MDC1 | REACTOME; |
reacts with |
MRE11A | NCI_NATURE; |
reacts with |
NBN | NCI_NATURE; |
reacts with |
RAD50 | NCI_NATURE; |
reacts with |
RBBP8 | NCI_NATURE; |
reacts with |
RNF8 | NCI_NATURE; |
reacts with |
TP53BP1 | IMID; |
reacts with |
TP53BP1 | NCI_NATURE; |
reacts with |
TP53BP1 | REACTOME; |
reacts with |
UIMC1 | NCI_NATURE; |
reacts with |
YWHAH | IMID; |
state change |
AKT1 | IMID; |
state change |
MDC1 | REACTOME; |
state change |
MDM2 | IMID; |