| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7704 |
Name | ZBTB16 |
Synonym | PLZF|ZNF145;zinc finger and BTB domain containing 16;ZBTB16;zinc finger and BTB domain containing 16 |
Definition | promyelocytic leukaemia zinc finger|zinc finger and BTB domain-containing protein 16|zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)|zinc finger protein PLZF |
Position | 11q23.1 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 18011 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
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Pathways and Diseases |
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Pathway | map kinase inactivation of smrt corepressor;PID BioCarta;100032 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
Disease | Cancers;KEGG DISEASE |
Disease | PSYCH;GAD |
Disease | Acute myeloid leukemia (AML);KEGG DISEASE;H00003 |
Disease | Cancers of haematopoietic and lymphoid tissues;KEGG DISEASE |
Disease | Conduct disorder (interaction);NHGRI |
Disease | Conduct disorder (interaction);GAD |
Disease | Leukemia, acute promyelocytic, PL2F/RARA type;OMIM |
Disease | Skeletal defects, genital hypoplasia, and mental retardation;OMIM |
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External Links |
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Links to Entrez Gene | 7704 |
Links to all GeneRIF Items | 7704 |
Links to iHOP | 7704 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7704 : length: 2022 atggatctgacaaaaatgggcatgatccagctgcagaaccctagccaccccacggggcta ctgtgcaaggccaaccagatgcggctggccgggactttgtgcgatgtggtcatcatggtg gacagccaggagttccacgcccaccggacggtgctggcctgcaccagcaagatgtttgag atcctcttccaccgcaatagtcaacactatactttggacttcctctcgccaaagaccttc cagcagattctggagtatgcatatacagccacgctgcaagccaaggcggaggacctggat gacctgctgtatgcggccgagatcctggagatcgagtacctggaggaacagtgcctgaag atgctggagaccatccaggcctcagacgacaatgacacggaggccaccatggccgatggc ggggccgaggaagaagaggaccgcaaggctcggtacctcaagaacatcttcatctcgaag cattccagcgaggagagtgggtatgccagtgtggctggacagagcctccctgggcccatg gtggaccagagcccttcagtctccacttcatttggtctttcagccatgagtcccaccaag gctgcagtggacagtttgatgaccataggacagtctctcctgcagggaactcttcagcca cctgcagggcccgaggagccaactctggctgggggtgggcggcaccctggggtggctgag gtgaagacggagatgatgcaggtggatgaggtgcccagccaggacagccctggggcagcc gagtccagcatctcaggagggatgggggacaaggttgaggaaagaggcaaagaggggcct gggaccccgactcgaagcagcgtcatcaccagtgctagggagctacactatgggcgagag gagagtgccgagcaggtgccacccccagctgaggctggccaggcccccactggccgacct gagcacccagcacccccgcctgagaagcatctgggcatctactccgtgttgcccaaccac aaggctgacgctgtattgagcatgccgtcttccgtgacctctggcctccacgtgcagcct gccctggctgtctccatggacttcagcacctatggggggctgctgccccagggcttcatc cagagggagctgttcagcaagctgggggagctggctgtgggcatgaagtcagagagccgg accatcggagagcagtgcagcgtgtgtggggtcgagcttcctgataacgaggctgtggag cagcacaggaagctgcacagtgggatgaagacgtacgggtgcgagctctgcgggaagcgg ttcctggatagtttgcggctgagaatgcacttactggctcattcagcgggtgccaaagcc tttgtctgtgatcagtgcggtgcacagttttcgaaggaggatgccctggagacacacagg cagacccatactggcactgacatggccgtcttctgtctgctgtgtgggaagcgcttccag gcgcagagcgcactgcagcagcacatggaggtccacgcgggcgtgcgcagctacatctgc agtgagtgcaaccgcaccttccccagccacacggctctcaaacgccacctgcgctcacat acaggcgaccacccctacgagtgtgagttctgtggcagctgcttccgggatgagagcaca ctcaagagccacaaacgcatccacacgggtgagaaaccctacgagtgcaatggctgtggc aagaagttcagcctcaagcatcagctggagacgcactatagggtgcacacaggtgagaag ccctttgagtgtaagctctgccaccagcgctcccgggactactcggccatgatcaagcac ctgagaacgcacaacggcgcctcgccctaccagtgcaccatctgcacagagtactgcccc agcctctcctccatgcagaagcacatgaagggccacaagcccgaggagatcccgcccgac tggaggatagagaagacgtacctctacctgtgctatgtgtga |
Protein Sequence |
>7704 : length: 673 MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFE ILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQCLK MLETIQASDDNDTEATMADGGAEEEEDRKARYLKNIFISKHSSEESGYASVAGQSLPGPM VDQSPSVSTSFGLSAMSPTKAAVDSLMTIGQSLLQGTLQPPAGPEEPTLAGGGRHPGVAE VKTEMMQVDEVPSQDSPGAAESSISGGMGDKVEERGKEGPGTPTRSSVITSARELHYGRE ESAEQVPPPAEAGQAPTGRPEHPAPPPEKHLGIYSVLPNHKADAVLSMPSSVTSGLHVQP ALAVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQCSVCGVELPDNEAVE QHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHR QTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSH TGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEK PFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPD WRIEKTYLYLCYV |