| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7704 |
Name | ZBTB16 |
Synonymous | PLZF|ZNF145;zinc finger and BTB domain containing 16;ZBTB16;zinc finger and BTB domain containing 16 |
Definition | promyelocytic leukaemia zinc finger|zinc finger and BTB domain-containing protein 16|zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)|zinc finger protein PLZF |
Position | 11q23.1 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for ZBTB16 | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
Cdk1(h) + PLZF(h) <==> PLZF(h):Cdk1(h) (binding) | PLZF(h) + MTG8(h) <==> PLZF(h):MTG8(h) (binding) | p300(h) + PLZF(h) <==> p300(h):PLZF(h) (binding) | PLZF(h) + p/CAF(m.s.) <==> PLZF(h):p/CAF(m.s.) (binding) | PLZF(h) + acetyl-CoA --p300(m.s.)--> CoA + PLZF(h){aceK} (acetylation) | PLZF(h) + acetyl-CoA --p300(h)--> PLZF(h){aceK} + CoA (acetylation) | PLZF(h) + NCOR1(h) <==> PLZF(h):NCOR1(h) (binding) | PLZF(h) + SMRT(h) <==> PLZF(h):SMRT(h) (binding) | HDAC1(m.s.) + PLZF(h) <==> HDAC1(m.s.):PLZF(h) (binding) | PLZF(h) + NCOR1(m) <==> PLZF(h):NCOR1(m) (binding) | PLZF(h) + sumo1(h) --> PLZF(h){sumoK242} (sumoylation) | PLZF(h) + AT2(r) <==> PLZF(h):AT2(r) (binding) | PLZF(h) + VDR(h) <==> VDR(h):PLZF(h) (binding) | PLZF(h) + sin3a(h) <==> PLZF(h):sin3a(h) (binding) | VDR(h) + PLZF(h) <==> VDR(h):PLZF(h) (binding) | MAGE11(h) + PLZF(h) <==> MAGE11(h):PLZF(h) (binding) | PLSCR1(h) + PLZF(h) <==> PLSCR1(h):PLZF(h) (binding) | RFP(h) + PLZF(h) <==> RFP(h):PLZF(h) (binding) | TRAF2(h) + PLZF(h) <==> TRAF2(h):PLZF(h) (binding) | PLZF(h) + SPOP(h) <==> PLZF(h):SPOP(h) (binding) | PLZF(h) + DIPA(h) <==> PLZF(h):DIPA(h) (binding) | PLZF(h) + BCUR1(h) <==> PLZF(h):BCUR1(h) (binding) | PLZF(h) + My012(h) <==> PLZF(h):My012(h) (binding) | PLZF(h) + cNOX(h) <==> PLZF(h):cNOX(h) (binding) | PLZF(h) + cep72(h) <==> PLZF(h):cep72(h) (binding) | PLZF(h) + cep70(h) <==> PLZF(h):cep70(h) (binding) | PLZF(h) + KAP4.12(h) <==> PLZF(h):KAP4.12(h) (binding) | PLZF(h) --> Kit(m) (DNA binding). | PLZF(h) --/ MIRN221(h) (DNA binding; transrepression). | PLZF(h) --/ MIRN222(h) (DNA binding; transrepression). | PLZF(h) --/ ATP6AP2(h) (DNA binding; transrepression). | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial(h) + PLZF(h) <==> dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial(h):PLZF(h) (binding) | Trap-2(h) + PLZF(h) <==> Trap-2(h):PLZF(h) (binding) | S9(h) + PLZF(h) <==> S9(h):PLZF(h) (binding) | ZNF-24(h) + PLZF(h) <==> ZNF-24(h):PLZF(h) (binding) | CD81(h) + PLZF(h) <==> CD81(h):PLZF(h) (binding) | platelet-activating factor acetylhydrolase IB subunit gamma(h) + PLZF(h) <==> platelet-activating factor acetylhydrolase IB subunit gamma(h):PLZF(h) (binding) | lyar(h) + PLZF(h) <==> lyar(h):PLZF(h) (binding) | pgam5(h) + PLZF(h) <==> pgam5(h):PLZF(h) (binding) | ZBTB16(h) --> PLZF(h) (expression). | PLZFB(h) --/ HOXB2(m) (DNA binding; transrepression). | PLZFB(h) --/ IL3RA(m) (DNA binding; transrepression). | PLZFB(h) + GATA-2(h) <==> PLZFB(h):GATA-2(h) (binding) | PLZFB(h) + AT2(r) <==> PLZFB(h):AT2(r) (binding) | ZBTB16(h) --> PLZFB(h) (expression). | ZBTB16(h) --> PLZFA(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
76 | Phosphoserine (by PDPK) (Potential). | Swiss-Prot 53.0 | 184 | Phosphoserine (by PDPK) (Potential). | Swiss-Prot 53.0 | 197 | Phosphoserine (by PDPK) (Potential). | Swiss-Prot 53.0 | 256 | Phosphoserine (by PDPK) (Potential). | Swiss-Prot 53.0 | 282 | Phosphothreonine (by PDPK) (Potential). | Swiss-Prot 53.0 | 628 | Phosphoserine (by PDPK) (Potential). | Swiss-Prot 53.0 |
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Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 113434998 - 113436998 | Agilent_014791 |
chr11 |
Promoter: 113434141 - 113436141 | Agilent_014791 |
chr11 |
Promoter: 113434141 - 113436141 | GSE27584 |
chr11 |
Promoter: 113434998 - 113436998 | GSE27584 |
chr11 |
Promoter: 113434998 - 113436998 | Agilent_014791_44K |