General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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---|---|
Gene ID | 8453 |
Name | CUL2 |
Synonym | -;cullin 2;CUL2;cullin 2 |
Definition | CUL-2|cullin-2 |
Position | 10p11.21 |
Gene Type | protein-coding |
TSG scores |
Description |
TUSON ranking | 969 |
TUSON P-value | 0.041120417 |
Pathways and Diseases |
|
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha;PID Curated;200122 |
External Links |
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Links to Entrez Gene | 8453 |
Links to all GeneRIF Items | 8453 |
Links to iHOP | 8453 |
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8453 : length: 2238 atgtctttgaaaccaagagtagtagattttgatgaaacatggaacaaacttttgacgaca ataaaagccgtggtcatgttggaatacgtcgaaagagcaacatggaatgaccgtttctca gatatctatgctttatgtgtggcctatcctgaaccccttggagaaagactttatacagaa actaagatttttttggaaaatcatgttcggcatttgcataagagagttttggagtcagaa gaacaagtacttgttatgtatcataggtactgggaagaatacagcaagggtgcagactat atggactgcttatataggtatctcaacacccagtttattaaaaagaataaattaacagaa gcggaccttcagtatggctatggtggtgtagatatgaatgaaccacttatggaaatagga gagctagcattggatatgtggaggaaattgatggttgaaccacttcaggccatccttatc cgaatgctgctccgagaaatcaaaaatgatcgtggtggagaagacccaaaccagaaagta atccatggggttattaactcctttgttcatgttgaacagtataagaaaaaattcccctta aagttttatcaggaaatttttgagtctccctttctgactgaaacaggagagtattacaaa caagaagcttcaaatttattacaagaatcaaactgctcacagtatatggaaaaggttcta ggtagattaaaagatgaagaaattcgatgtcgaaaatacctacatccaagttcatatact aaggtgattcatgaatgtcaacaacgaatggtagcagaccacttacagtttttacatgca gaatgtcataatataattcgacaagagaaaaaaaatgacatggcaaatatgtacgtctta ctccgtgctgtgtccactggtttacctcatatgattcaggagctgcaaaaccacatccat gatgagggccttcgagcaaccagcaaccttactcaggaaaacatgccaacactatttgtg gagtcagttttggaagtgcatggtaaatttgttcagcttatcaacactgttttgaatggt gatcagcattttatgagtgcgttggataaggcccttacgtcagttgtaaattacagagaa cctaagtctgtttgcaaagcacctgaactgcttgctaagtactgtgacaacttactgaag aagtcagcgaaagggatgacagagaatgaagtggaagacaggctcacgagcttcatcaca gtgttcaaatacattgatgacaaggacgtctttcaaaagttctacgcaagaatgctggca aaacgtttaattcatgggttatccatgtctatggactctgaagaagccatgatcaacaaa ttaaagcaagcctgtggttatgagtttaccagcaagctacatcggatgtatacagatatg agtgtcagcgctgatctcaacaataagttcaacaattttatcaaaaaccaagacacagta atagatttgggaattagttttcaaatatatgttctacaggctggtgcgtggcctcttact caggctccttcatctacgtttgcaattccccaggaattagaaaaaagtgtacagatgttt gaattattttatagccaacatttcagtggaaggaaacttacatggttacattatctgtgt acaggtgaagttaaaatgaactatttgggcaaaccatatgtagccatggttacaacatac caaatggcagttcttcttgcctttaacaacagtgaaactgtcagttataaagagcttcag gacagcactcagatgaatgaaaaggaactgacaaaaacaatcaaatcattacttgatgtg aaaatgattaaccatgattcagaaaaggaagatattgatgcagaatcttcgttttcatta aatatgaactttagcagtaaaagaacaaaatttaaaattactacatcaatgcagaaagac acaccacaagaaatggagcagactagaagtgcagttgatgaggaccggaaaatgtatctc caagctgctatagttcgtatcatgaaagcacgaaaagtgcttcggcacaatgcccttatt caagaggtgattagccagtcaagagctaggtttaatcccagtatcagcatgattaagaag tgtattgaagttctgatagacaaacaatacatagaacgcagccaggcgtcggcagatgaa tacagctacgtcgcgtga |
Protein Sequence |
>8453 : length: 745 MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTE TKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTE ADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVL GRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHAECHNIIRQEKKNDMANMYVL LRAVSTGLPHMIQELQNHIHDEGLRATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNG DQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFIT VFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDM SVSADLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMF ELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQ DSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKD TPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKK CIEVLIDKQYIERSQASADEYSYVA |