Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8453

Name

CUL2

Synonymous

-;cullin 2;CUL2;cullin 2

Definition

CUL-2|cullin-2

Position

10p11.21

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Cul-2(h) + Murr1(h) <==> Cul-2(h):Murr1(h) (binding)
VHL(h) + Cul-2(h) <==> VHL(h):Cul-2(h) (binding)
Cul-2(h) + PDI(h) <==> Cul-2(h):PDI(h) (binding)
Cul-2(h) + MO25(h) <==> Cul-2(h):MO25(h) (binding)
TFEA(h) + Cul-2(h) <==> TFEA(h):Cul-2(h) (binding)
Cul-2(h) + TIM13(h) <==> Cul-2(h):TIM13(h) (binding)
Cul-2(h) + STOM(h) <==> Cul-2(h):STOM(h) (binding)
SAP102(h) + Cul-2(h) <==> SAP102(h):Cul-2(h) (binding)
Cul-2(h) + 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3(h) <==> Cul-2(h):6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3(h) (binding)
Cul-2(h) + CMBL(h) <==> Cul-2(h):CMBL(h) (binding)
Cul-2(h) + HC90(h) <==> Cul-2(h):HC90(h) (binding)
Cul-2(h) + KCTD5(h) <==> Cul-2(h):KCTD5(h) (binding)
CUL2(h) --> Cul-2(h) (expression).
CUL2(h) --> Cul-2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

689Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in NEDD8).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 35418800 - 35420800Agilent_014791

chr10

Promoter: 35418800 - 35420800GSE27584

chr10

Promoter: 35418800 - 35420800Agilent_014791_44K


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