| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8554 |
Name | PIAS1 |
Synonym | DDXBP1|GBP|GU/RH-II|ZMIZ3;protein inhibitor of activated STAT, 1;PIAS1;protein inhibitor of activated STAT, 1 |
Definition | AR interacting protein|DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1|DEAD/H box-binding protein 1|E3 SUMO-protein ligase PIAS1|RNA helicase II-binding protein|gu-binding protein|protein inhibitor of activated STAT protein 1|protein inhibitor of activ |
Position | 15q |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 12755 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | Hedgehog signaling events mediated by Gli proteins;PID Curated;200147 |
Pathway | Small cell lung cancer;KEGG PATHWAY;hsa05222 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | Sumoylation by RanBP2 regulates transcriptional repression;PID Curated;200097 |
Pathway | Interferon-gamma signaling pathway;PANTHER;P00035 |
Pathway | Coregulation of Androgen receptor activity;PID Curated;200038 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | JAK/STAT signaling pathway;PANTHER;P00038 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | IFN-gamma pathway;PID Curated;200110 |
Pathway | sumoylation by ranbp2 regulates transcriptional repression;PID BioCarta;100053 |
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External Links |
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Links to Entrez Gene | 8554 |
Links to all GeneRIF Items | 8554 |
Links to iHOP | 8554 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8554 : length: 1956 atggcggacagtgcggaactaaagcaaatggttatgagccttagagtttctgaactccaa gtactgttgggctacgccgggagaaacaagcacggacgcaaacacgaacttctcacaaaa gccctgcatttgctaaaggctggctgtagtcctgctgtgcaaatgaaaattaaggaactc tataggcggcggttcccacagaaaatcatgacgcctgcagacttgtccatccccaacgta cattcaagtcctatgccagcaactttgtctccatctaccattccacaactcacttacgat ggtcaccctgcatcatcgccattactccctgtttctcttctgggacctaaacatgaactg gaactcccacatcttacatcagctcttcacccagtccatccggatataaaacttcaaaaa ttaccattttatgatttactggatgaactgataaaacccaccagtctagcatcagacaac agtcagcgctttcgagaaacctgttttgcatttgccttgacaccacaacaagtgcagcaa atcagtagttccatggatatttctgggaccaaatgtgacttcacagtacaggtccagtta aggttttgtttatcagaaaccagttgtccacaagaagatcacttcccacccaatctttgt gtgaaagtgaatacaaaaccttgcagccttccaggttaccttccacctacaaaaaatggc gtggaaccaaagcgacccagccgaccaattaatatcacctcacttgtccgactgtccaca acagtaccaaacacgattgttgtttcttggactgcagaaattggaagaaactattccatg gcagtatatcttgtaaaacagttgtcctcaacagttcttcttcagaggttacgagcaaag ggaataaggaatccggatcattctagagctttaattaaagagaagttgactgcggatcca gacagtgaaatagctacaaccagcctaagggtttctctactatgtccacttggtaaaatg cggctgacaattccgtgtcgggcccttacatgttctcatctacaatgttttgacgcaact ctttacattcagatgaatgagaaaaaaccaacctgggtttgtcctgtctgtgataagaag gctccatatgaacaccttattattgatggcttgtttatggaaatcctaaagtactgtaca gactgtgatgaaatacaatttaaggaggatggcacttgggcaccgatgagatcaaaaaag gaagtacaggaagtttctgcctcttacaatggagtcgatggatgcttgagctccacattg gagcatcaggtagcgtctcaccaccagtcctcaaataaaaacaagaaagtagaagtgatt gacctaaccatagacagttcatctgatgaagaggaagaagagccatctgccaagaggacc tgtccttccctatctcccacatcaccactaaataataaaggcattttaagtcttccacat caagcatctccagtatcccgcaccccaagccttcctgctgtagacacaagctacattaat acctccctcatccaagactataggcatcctttccacatgacacccatgccttacgactta caaggattagatttctttcctttcttatcaggagacaatcagcattacaacacctccttg cttgccgctgcagcagcagcagtttcagatgatcaagacctcctacactcgtctcggttt ttcccgtatacctcctcacagatgtttcttgatcagttaagtgcaggaggcagtacttct ctgccaaccaccaatggaagcagtagtggcagtaacagcagcctggtttcttccaacagc ctaagggaaagccatagccacaccgtcacaaacaggagcagcacggacacggcatccatc tttggcatcataccagacattatttcattggactga |
Protein Sequence |
>8554 : length: 651 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD |