Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8742

Name

TNFSF12

Synonym

APO3L|DR3LG|TWEAK;tumor necrosis factor (ligand) superfamily, member 12;TNFSF12;tumor necrosis factor (ligand) superfamily, member 12

Definition

APO3 ligand|APO3/DR3 ligand|TNF-related WEAK inducer of apoptosis|tumor necrosis factor ligand superfamily member 12

Position

17p13

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

16859

TUSON P-value

1

Pathways and Diseases

Pathway

Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060

Pathway

induction of apoptosis through dr3 and dr4/5 death receptors;PID BioCarta;100189

External Links

Links to Entrez Gene

8742

Links to all GeneRIF Items

8742

Links to iHOP

8742

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>8742 : length: 750
atggccgcccgtcggagccagaggcggagggggcgccggggggagccgggcaccgccctg
ctggtcccgctcgcgctgggcctgggcctggcgctggcctgcctcggcctcctgctggcc
gtggtcagtttggggagccgggcatcgctgtccgcccaggagcctgcccaggaggagctg
gtggcagaggaggaccaggacccgtcggaactgaatccccagacagaagaaagccaggat
cctgcgcctttcctgaaccgactagttcggcctcgcagaagtgcacctaaaggccggaaa
acacgggctcgaagagcgatcgcagcccattatgaagttcatccacgacctggacaggac
ggagcgcaggcaggtgtggacgggacagtgagtggctgggaggaagccagaatcaacagc
tccagccctctgcgctacaaccgccagatcggggagtttatagtcacccgggctgggctc
tactacctgtactgtcaggtgcactttgatgaggggaaggctgtctacctgaagctggac
ttgctggtggatggtgtgctggccctgcgctgcctggaggaattctcagccactgcggcg
agttccctcgggccccagctccgcctctgccaggtgtctgggctgttggccctgcggcca
gggtcctccctgcggatccgcaccctcccctgggcccatctcaaggctgcccccttcctc
acctacttcggactcttccaggttcactga

Protein Sequence

>8742 : length: 249
MAARRSQRRRGRRGEPGTALLVPLALGLGLALACLGLLLAVVSLGSRASLSAQEPAQEEL
VAEEDQDPSELNPQTEESQDPAPFLNRLVRPRRSAPKGRKTRARRAIAAHYEVHPRPGQD
GAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLD
LLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFL
TYFGLFQVH



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