Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8742

Name

TNFSF12

Synonymous

APO3L|DR3LG|TWEAK;tumor necrosis factor (ligand) superfamily, member 12;TNFSF12;tumor necrosis factor (ligand) superfamily, member 12

Definition

APO3 ligand|APO3/DR3 ligand|TNF-related WEAK inducer of apoptosis|tumor necrosis factor ligand superfamily member 12

Position

17p13

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

TNFSF12(h) --> TWEAK(h) (expression).
TWEAK(h) --/ TRAF2(h) (decrease of abundance)
TWEAK(h) --/ TRAF2(m) (decrease of abundance)
TNFSF12(h) --> TWEAK(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

139N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr17

Promoter: 7391599 - 7393599Agilent_014791

chr17

Promoter: 7391599 - 7393599GSE27584


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