| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8797 |
Name | TNFRSF10A |
Synonym | APO2|CD261|DR4|TRAILR-1|TRAILR1;tumor necrosis factor receptor superfamily, member 10a;TNFRSF10A;tumor necrosis factor receptor superfamily, member 10a |
Definition | TNF-related apoptosis-inducing ligand receptor 1|TRAIL receptor 1|TRAIL-R1|cytotoxic TRAIL receptor|death receptor 4|tumor necrosis factor receptor superfamily member 10A|tumor necrosis factor receptor superfamily member 10a variant 2 |
Position | 8p21 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16837 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | TRAIL signaling pathway;PID Curated;200056 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Disease | CANCER;GAD |
Disease | Emphysema;FunDO |
Disease | Pancreatitis;FunDO |
Disease | breast cancer;GAD |
Disease | leukemia, chronic lymphocytic;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | Adenovirus infection;FunDO |
Disease | Asthma;FunDO |
Disease | Cancer;FunDO |
Disease | chronic lymphocytic leukaemia;GAD |
Disease | Leukoencephalopathy;FunDO |
|
External Links |
|
Links to Entrez Gene | 8797 |
Links to all GeneRIF Items | 8797 |
Links to iHOP | 8797 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8797 : length: 1407 atggcgccaccaccagctagagtacatctaggtgcgttcctggcagtgactccgaatccc gggagcgcagcgagtgggacagaggcagccgcggccacacccagcaaagtgtggggctct tccgcggggaggattgaaccacgaggcgggggccgaggagcgctccctacctccatggga cagcacggacccagtgcccgggcccgggcagggcgcgccccaggacccaggccggcgcgg gaagccagccctcggctccgggtccacaagaccttcaagtttgtcgtcgtcggggtcctg ctgcaggtcgtacctagctcagctgcaaccatcaaacttcatgatcaatcaattggcaca cagcaatgggaacatagccctttgggagagttgtgtccaccaggatctcatagatcagaa catcctggagcctgtaaccggtgcacagagggtgtgggttacaccaatgcttccaacaat ttgtttgcttgcctcccatgtacagcttgtaaatcagatgaagaagagagaagtccctgc accacgaccaggaacacagcatgtcagtgcaaaccaggaactttccggaatgacaattct gctgagatgtgccggaagtgcagcagagggtgccccagagggatggtcaaggtcaaggat tgtacgccctggagtgacatcgagtgtgtccacaaagaatcaggcaatggacataatata tgggtgattttggttgtgactttggttgttccgttgctgttggtggctgtgctgattgtc tgttgttgcatcggctcaggttgtggaggggaccccaagtgcatggacagggtgtgtttc tggcgcttgggtctcctacgagggcctggggctgaggacaatgctcacaacgagattctg agcaacgcagactcgctgtccactttcgtctctgagcagcaaatggaaagccaggagccg gcagatttgacaggtgtcactgtacagtccccaggggaggcacagtgtctgctgggaccg gcagaagctgaagggtctcagaggaggaggctgctggttccagcaaatggtgctgacccc actgagactctgatgctgttctttgacaagtttgcaaacatcgtgccctttgactcctgg gaccagctcatgaggcagctggacctcacgaaaaatgagatcgatgtggtcagagctggt acagcaggcccaggggatgccttgtatgcaatgctgatgaaatgggtcaacaaaactgga cggaacgcctcgatccacaccctgctggatgccttggagaggatggaagagagacatgca agagagaagattcaggacctcttggtggactctggaaagttcatctacttagaagatggc acaggctctgccgtgtccttggagtga |
Protein Sequence |
>8797 : length: 468 MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMG QHGPSARARAGRAPGPRPAREASPRLRVHKTFKFVVVGVLLQVVPSSAATIKLHDQSIGT QQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPC TTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHNI WVILVVTLVVPLLLVAVLIVCCCIGSGCGGDPKCMDRVCFWRLGLLRGPGAEDNAHNEIL SNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADP TETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLMKWVNKTG RNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE |