| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8841 |
Name | HDAC3 |
Synonym | HD3|RPD3|RPD3-2;histone deacetylase 3;HDAC3;histone deacetylase 3 |
Definition | SMAP45 |
Position | 5q31 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 8271 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Regulation of retinoblastoma protein;PID Curated;200191 |
Pathway | Signaling events mediated by HDAC Class II;PID Curated;200019 |
Pathway | Signaling events mediated by HDAC Class I;PID Curated;200070 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells;PID BioCarta;100048 |
Pathway | Retinoic acid receptors-mediated signaling;PID Curated;200142 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | acetylation and deacetylation of rela in nucleus;PID BioCarta;100043 |
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Disease | Infection;FunDO |
Disease | Cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 8841 |
Links to all GeneRIF Items | 8841 |
Links to iHOP | 8841 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8841 : length: 1287 atggccaagaccgtggcctatttctacgaccccgacgtgggcaacttccactacggagct ggacaccctatgaagccccatcgcctggcattgacccatagcctggtcctgcattacggt ctctataagaagatgatcgtcttcaagccataccaggcctcccaacatgacatgtgccgc ttccactccgaggactacattgacttcctgcagagagtcagccccaccaatatgcaaggc ttcaccaagagtcttaatgccttcaacgtaggcgatgactgcccagtgtttcccgggctc tttgagttctgctcgcgttacacaggcgcatctctgcaaggagcaacccagctgaacaac aagatctgtgatattgccattaactgggctggtggtctgcaccatgccaagaagtttgag gcctctggcttctgctatgtcaacgacattgtgattggcatcctggagctgctcaagtac caccctcgggtgctctacattgacattgacatccaccatggtgacggggttcaagaagct ttctacctcactgaccgggtcatgacggtgtccttccacaaatacggaaattacttcttc cctggcacaggtgacatgtatgaagtcggggcagagagtggccgctactactgtctgaac gtgcccctgcgggatggcattgatgaccagagttacaagcaccttttccagccggttatc aaccaggtagtggacttctaccaacccacgtgcattgtgctccagtgtggagctgactct ctgggctgtgatcgattgggctgctttaacctcagcatccgagggcatggggaatgcgtt gaatatgtcaagagcttcaatatccctctactcgtgctgggtggtggtggttatactgtc cgaaatgttgcccgctgctggacatatgagacatcgctgctggtagaagaggccattagt gaggagcttccctatagtgaatacttcgagtactttgccccagacttcacacttcatcca gatgtcagcacccgcatcgagaatcagaactcacgccagtatctggaccagatccgccag acaatctttgaaaacctgaagatgctgaaccatgcacctagtgtccagattcatgacgtg cctgcagacctcctgacctatgacaggactgatgaggctgatgcagaggagaggggtcct gaggagaactatagcaggccagaggcacccaatgagttctatgatggagaccatgacaat gacaaggaaagcgatgtggagatttaa |
Protein Sequence |
>8841 : length: 428 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN DKESDVEI |