| General information | Literature | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8841 |
Name | HDAC3 |
Synonymous | HD3|RPD3|RPD3-2;histone deacetylase 3;HDAC3;histone deacetylase 3 |
Definition | SMAP45 |
Position | 5q31 |
Gene type | protein-coding |
|
Title |
Abstract |
| High resolution physical mapping of human HDAC3, a potential tumor suppressor gene in the 5q31 region. | Histone deacetylases have been described as crucial cofactors of mammalian transcriptional complexes. We have recently identified human histone deacetylase HDAC3 on chromosome 5q31 by fluorescence in situ hybridization (FISH) in a region commonly deleted in malignant myeloid disease. Since HDAC3 carries strong potential to be a tumor suppressor gene, we report herein its exact position between the CD14 and GRIA1 genes within the 5q31.1 subband. |