General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 1017 |
Name | CDK2 |
Synonymous | CDKN2|p33(CDK2);cyclin-dependent kinase 2;CDK2;cyclin-dependent kinase 2 |
Definition | cdc2-related protein kinase|cell division protein kinase 2|p33 protein kinase |
Position | 12q13 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ANAPC10 | REACTOME; |
in same component |
ANAPC11 | REACTOME; |
in same component |
ANAPC1 | REACTOME; |
in same component |
ANAPC2 | REACTOME; |
in same component |
ANAPC4 | REACTOME; |
in same component |
ANAPC5 | REACTOME; |
in same component |
ANAPC7 | REACTOME; |
in same component |
ATM | REACTOME; |
in same component |
CABLES1 | REACTOME; |
in same component |
CCNA2 | NCI_NATURE; |
in same component |
CCNE1 | CELL_MAP; |
in same component |
CCNE1 | NCI_NATURE; |
in same component |
CCNE1 | REACTOME; |
in same component |
CCNE2 | REACTOME; |
in same component |
CDC16 | REACTOME; |
in same component |
CDC23 | REACTOME; |
in same component |
CDC26 | REACTOME; |
in same component |
CDC27 | REACTOME; |
in same component |
CDC45 | REACTOME; |
in same component |
CDC6 | REACTOME; |
in same component |
CDC7 | REACTOME; |
in same component |
CDKN1A | NCI_NATURE; |
in same component |
CDKN1B | NCI_NATURE; |
in same component |
CEBPA | NCI_NATURE; |
in same component |
CKS1B | REACTOME; |
in same component |
CLSPN | REACTOME; |
in same component |
CUL1 | REACTOME; |
in same component |
DBF4 | REACTOME; |
in same component |
E2F4 | REACTOME; |
in same component |
FZR1 | REACTOME; |
in same component |
MCM10 | REACTOME; |
in same component |
MCM2 | REACTOME; |
in same component |
MCM3 | REACTOME; |
in same component |
MCM4 | REACTOME; |
in same component |
MCM5 | REACTOME; |
in same component |
MCM6 | REACTOME; |
in same component |
MCM7 | REACTOME; |
in same component |
MLH1 | REACTOME; |
in same component |
MLH3 | REACTOME; |
in same component |
ORC1 | REACTOME; |
in same component |
ORC2 | REACTOME; |
in same component |
ORC3 | REACTOME; |
in same component |
ORC4 | REACTOME; |
in same component |
ORC5 | REACTOME; |
in same component |
ORC6 | REACTOME; |
in same component |
RB1 | REACTOME; |
in same component |
RBL1 | REACTOME; |
in same component |
RBL2 | REACTOME; |
in same component |
RPA1 | REACTOME; |
in same component |
RPA2 | REACTOME; |
in same component |
RPA3 | REACTOME; |
in same component |
RPA4 | REACTOME; |
in same component |
SKP1 | REACTOME; |
in same component |
SKP2 | REACTOME; |
in same component |
UBE2C | REACTOME; |
in same component |
UBE2D1 | REACTOME; |
in same component |
UBE2E1 | REACTOME; |
in same component |
WEE1 | REACTOME; |
interacts with |
BCCIP | BIOGRID; |
interacts with |
BCCIP | HPRD; |
interacts with |
BCL2 | HPRD; |
interacts with |
BIRC5 | BIOGRID; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
BRCA2 | HPRD; |
interacts with |
CASP4 | BIOGRID; |
interacts with |
CCNA1 | BIOGRID; |
interacts with |
CCNA2 | BIOGRID; |
interacts with |
CCNA2 | CELL_MAP; |
interacts with |
CCNA2 | HPRD; |
interacts with |
CCNA2 | NCI_NATURE; |
interacts with |
CCNB1 | BIOGRID; |
interacts with |
CCNB2 | HPRD; |
interacts with |
CCNB2 | MINT; |
interacts with |
CCNB3 | BIOGRID; |
interacts with |
CCNB3 | HPRD; |
interacts with |
CCND1 | HPRD; |
interacts with |
CCNE1 | BIOGRID; |
interacts with |
CCNE1 | CELL_MAP; |
interacts with |
CCNE1 | HPRD; |
interacts with |
CCNE1 | INTACT; |
interacts with |
CCNE1 | MINT; |
interacts with |
CCNE2 | BIOGRID; |
interacts with |
CCNE2 | HPRD; |
interacts with |
CCNH | HPRD; |
interacts with |
CCNK | HPRD; |
interacts with |
CCP110 | HPRD; |
interacts with |
CDC25A | BIOGRID; |
interacts with |
CDC25A | HPRD; |
interacts with |
CDC25B | BIOGRID; |
interacts with |
CDC37 | HPRD; |
interacts with |
CDC5L | BIOGRID; |
interacts with |
CDC5L | HPRD; |
interacts with |
CDC6 | BIOGRID; |
interacts with |
CDC6 | HPRD; |
interacts with |
CDC7 | HPRD; |
interacts with |
CDK15 | BIOGRID; |
interacts with |
CDK20 | HPRD; |
interacts with |
CDK2AP1 | BIOGRID; |
interacts with |
CDK2AP1 | HPRD; |
interacts with |
CDK6 | BIOGRID; |
interacts with |
CDK7 | HPRD; |
interacts with |
CDKN1A | BIOGRID; |
interacts with |
CDKN1A | CELL_MAP; |
interacts with |
CDKN1A | HPRD; |
interacts with |
CDKN1A | MINT; |
interacts with |
CDKN1B | BIOGRID; |
interacts with |
CDKN1B | HPRD; |
interacts with |
CDKN1B | MINT; |
interacts with |
CDKN3 | BIOGRID; |
interacts with |
CDKN3 | HPRD; |
interacts with |
CDKN3 | MINT; |
interacts with |
CDT1 | BIOGRID; |
interacts with |
CDT1 | HPRD; |
interacts with |
CDX2 | HPRD; |
interacts with |
CEBPA | BIOGRID; |
interacts with |
CEBPA | HPRD; |
interacts with |
CHAF1A | BIOGRID; |
interacts with |
CHAF1A | HPRD; |
interacts with |
CHAF1A | MINT; |
interacts with |
CHAF1B | HPRD; |
interacts with |
CKS1B | BIOGRID; |
interacts with |
CKS1B | MINT; |
interacts with |
CKS1 | BIOGRID; |
interacts with |
CNOT7 | BIOGRID; |
interacts with |
CNOT7 | HPRD; |
interacts with |
CNTN2 | BIOGRID; |
interacts with |
COIL | HPRD; |
interacts with |
E2F1 | BIOGRID; |
interacts with |
E2F1 | HPRD; |
interacts with |
E2F4 | HPRD; |
interacts with |
EP300 | HPRD; |
interacts with |
EP300 | MINT; |
interacts with |
EPB41 | BIOGRID; |
interacts with |
ESR1 | HPRD; |
interacts with |
EZH2 | BIOGRID; |
interacts with |
FAM113A | BIOGRID; |
interacts with |
FBL | BIOGRID; |
interacts with |
FEN1 | BIOGRID; |
interacts with |
FEN1 | HPRD; |
interacts with |
FOXM1 | BIOGRID; |
interacts with |
FZR1 | HPRD; |
interacts with |
HIRA | HPRD; |
interacts with |
HIST1H1A | BIOGRID; |
interacts with |
HIST1H1B | HPRD; |
interacts with |
ID2 | CELL_MAP; |
interacts with |
ID2 | HPRD; |
interacts with |
ID3 | CELL_MAP; |
interacts with |
ID3 | HPRD; |
interacts with |
Ifi205b | MINT; |
interacts with |
IKBKG | BIOGRID; |
interacts with |
INCA1 | BIOGRID; |
interacts with |
INCA1 | HPRD; |
interacts with |
KAT2B | BIOGRID; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | HPRD; |
interacts with |
MCM3 | HPRD; |
interacts with |
MCM3 | MINT; |
interacts with |
MCM4 | BIOGRID; |
interacts with |
MCM4 | HPRD; |
interacts with |
MNDA | HPRD; |
interacts with |
MS4A3 | BIOGRID; |
interacts with |
MS4A3 | HPRD; |
interacts with |
Mybl2 | BIOGRID; |
interacts with |
MYBL2 | BIOGRID; |
interacts with |
MYBL2 | HPRD; |
interacts with |
MYOD1 | HPRD; |
interacts with |
NAA25 | BIOGRID; |
interacts with |
NEDD8 | BIOGRID; |
interacts with |
NFYA | HPRD; |
interacts with |
NOV | BIOGRID; |
interacts with |
NPAT | HPRD; |
interacts with |
NPDC1 | BIOGRID; |
interacts with |
NPDC1 | HPRD; |
interacts with |
OGT | BIOGRID; |
interacts with |
ORC1 | BIOGRID; |
interacts with |
ORC1 | HPRD; |
interacts with |
ORC2 | BIOGRID; |
interacts with |
ORC2 | HPRD; |
interacts with |
ORC2 | MINT; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
PIN1 | HPRD; |
interacts with |
POLA1 | BIOGRID; |
interacts with |
POLA1 | HPRD; |
interacts with |
POLD1 | HPRD; |
interacts with |
POLL | HPRD; |
interacts with |
PPM1B | BIOGRID; |
interacts with |
PPP2CA | BIOGRID; |
interacts with |
PPP2CB | HPRD; |
interacts with |
PRC1 | HPRD; |
interacts with |
PRKAR1A | HPRD; |
interacts with |
PRKCH | BIOGRID; |
interacts with |
PRKCH | HPRD; |
interacts with |
PTHLH | HPRD; |
interacts with |
PTP4A3 | BIOGRID; |
interacts with |
RADIL | BIOGRID; |
interacts with |
RB1 | BIOGRID; |
interacts with |
RB1 | HPRD; |
interacts with |
RB1 | INTACT; |
interacts with |
RBL1 | BIOGRID; |
interacts with |
RBL1 | CELL_MAP; |
interacts with |
RBL1 | HPRD; |
interacts with |
RBL2 | BIOGRID; |
interacts with |
RBL2 | HPRD; |
interacts with |
RBM4 | BIOGRID; |
interacts with |
REL | BIOGRID; |
interacts with |
RMP | HPRD; |
interacts with |
RRN3 | BIOGRID; |
interacts with |
SKP2 | BIOGRID; |
interacts with |
SKP2 | HPRD; |
interacts with |
SORT1 | BIOGRID; |
interacts with |
SP1 | BIOGRID; |
interacts with |
SPDYA | BIOGRID; |
interacts with |
SPDYA | HPRD; |
interacts with |
STAP1 | HPRD; |
interacts with |
TFDP1 | HPRD; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TP73 | HPRD; |
interacts with |
TSC22D1 | BIOGRID; |
interacts with |
TSPYL2 | BIOGRID; |
interacts with |
TSPYL2 | HPRD; |
interacts with |
UBE2A | BIOGRID; |
interacts with |
UBE2M | BIOGRID; |
interacts with |
UBTF | HPRD; |
interacts with |
UHRF2 | HPRD; |
interacts with |
VHL | BIOGRID; |
interacts with |
WEE1 | HPRD; |
interacts with |
WRAP73 | BIOGRID; |
interacts with |
XRCC6 | BIOGRID; |
Metabolic Interaction [Top] | ||
There is no record for CDK2 |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ANAPC10 | REACTOME; |
reacts with |
ANAPC11 | REACTOME; |
reacts with |
ANAPC1 | REACTOME; |
reacts with |
ANAPC2 | REACTOME; |
reacts with |
ANAPC4 | REACTOME; |
reacts with |
ANAPC5 | REACTOME; |
reacts with |
ANAPC7 | REACTOME; |
reacts with |
ATM | REACTOME; |
reacts with |
BLM | REACTOME; |
reacts with |
BRCA2 | REACTOME; |
reacts with |
CABLES1 | REACTOME; |
reacts with |
CCNE1 | REACTOME; |
reacts with |
CCNE2 | REACTOME; |
reacts with |
CDC16 | REACTOME; |
reacts with |
CDC23 | REACTOME; |
reacts with |
CDC26 | REACTOME; |
reacts with |
CDC27 | REACTOME; |
reacts with |
CDC45 | REACTOME; |
reacts with |
CDC6 | REACTOME; |
reacts with |
CDC7 | REACTOME; |
reacts with |
CDK2 | NCI_NATURE; |
reacts with |
CDK2 | REACTOME; |
reacts with |
CDK4 | REACTOME; |
reacts with |
CDKN1A | NCI_NATURE; |
reacts with |
CDKN1B | NCI_NATURE; |
reacts with |
CEBPA | NCI_NATURE; |
reacts with |
CKS1B | REACTOME; |
reacts with |
CLSPN | REACTOME; |
reacts with |
CUL1 | REACTOME; |
reacts with |
DBF4 | REACTOME; |
reacts with |
E2F4 | REACTOME; |
reacts with |
FZR1 | REACTOME; |
reacts with |
MCM10 | REACTOME; |
reacts with |
MCM2 | REACTOME; |
reacts with |
MCM3 | REACTOME; |
reacts with |
MCM4 | REACTOME; |
reacts with |
MCM5 | REACTOME; |
reacts with |
MCM6 | REACTOME; |
reacts with |
MCM7 | REACTOME; |
reacts with |
MLH1 | REACTOME; |
reacts with |
MLH3 | REACTOME; |
reacts with |
MSH4 | REACTOME; |
reacts with |
MSH5 | REACTOME; |
reacts with |
ORC1 | REACTOME; |
reacts with |
ORC2 | REACTOME; |
reacts with |
ORC3 | REACTOME; |
reacts with |
ORC4 | REACTOME; |
reacts with |
ORC5 | REACTOME; |
reacts with |
ORC6 | REACTOME; |
reacts with |
RB1 | REACTOME; |
reacts with |
RBL1 | REACTOME; |
reacts with |
RBL2 | REACTOME; |
reacts with |
RPA1 | REACTOME; |
reacts with |
RPA2 | REACTOME; |
reacts with |
RPA3 | REACTOME; |
reacts with |
RPA4 | REACTOME; |
reacts with |
SKP1 | REACTOME; |
reacts with |
SKP2 | REACTOME; |
reacts with |
SMARCA2 | NCI_NATURE; |
reacts with |
TOP3A | REACTOME; |
reacts with |
UBE2C | REACTOME; |
reacts with |
UBE2D1 | REACTOME; |
reacts with |
UBE2E1 | REACTOME; |
reacts with |
WEE1 | REACTOME; |
state change |
ANAPC10 | REACTOME; |
state change |
ANAPC11 | REACTOME; |
state change |
ANAPC1 | REACTOME; |
state change |
ANAPC2 | REACTOME; |
state change |
ANAPC4 | REACTOME; |
state change |
ANAPC5 | REACTOME; |
state change |
ANAPC7 | REACTOME; |
state change |
ATRIP | REACTOME; |
state change |
CDC16 | REACTOME; |
state change |
CDC23 | REACTOME; |
state change |
CDC25A | REACTOME; |
state change |
CDC26 | REACTOME; |
state change |
CDC27 | REACTOME; |
state change |
CDK2 | REACTOME; |
state change |
CKS1B | REACTOME; |
state change |
CUL1 | REACTOME; |
state change |
FZR1 | REACTOME; |
state change |
PKMYT1 | REACTOME; |
state change |
RB1 | REACTOME; |
state change |
SKP1 | REACTOME; |
state change |
SKP2 | REACTOME; |
state change |
UBE2C | REACTOME; |
state change |
UBE2D1 | REACTOME; |
state change |
UBE2E1 | REACTOME; |