Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1027

Name

CDKN1B

Synonymous

CDKN4|KIP1|MEN1B|MEN4|P27KIP1;cyclin-dependent kinase inhibitor 1B (p27, Kip1);CDKN1B;cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Definition

cyclin-dependent kinase inhibitor 1B

Position

12p13.1-p12

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 CDK2NCI_NATURE;

in same component

 KPNA1NCI_NATURE;

in same component

 SKP2NCI_NATURE;

interacts with

 AKT1BIOGRID;

interacts with

 AKT1HPRD;

interacts with

 AKT1MINT;

interacts with

 AKT1NCI_NATURE;

interacts with

 ARHGDIABIOGRID;

interacts with

 ARHGDIAHPRD;

interacts with

 ARHGDIAMINT;

interacts with

 CASP8HPRD;

interacts with

 CCNA1BIOGRID;

interacts with

 CCNA2BIOGRID;

interacts with

 CCNA2HPRD;

interacts with

 CCNB1HPRD;

interacts with

 CCND1BIOGRID;

interacts with

 CCND1HPRD;

interacts with

 CCND2BIOGRID;

interacts with

 CCND2HPRD;

interacts with

 CCND2MINT;

interacts with

 CCND3BIOGRID;

interacts with

 CCND3HPRD;

interacts with

 CCNE1BIOGRID;

interacts with

 CCNE1HPRD;

interacts with

 CCNE2HPRD;

interacts with

 CDC34BIOGRID;

interacts with

 CDK2BIOGRID;

interacts with

 CDK2HPRD;

interacts with

 CDK2MINT;

interacts with

 CDK3HPRD;

interacts with

 CDK4BIOGRID;

interacts with

 CDK4HPRD;

interacts with

 CDK4MINT;

interacts with

 CDK6BIOGRID;

interacts with

 CKS1BBIOGRID;

interacts with

 COPS5BIOGRID;

interacts with

 COPS5HPRD;

interacts with

 CUL4ABIOGRID;

interacts with

 CUL4AHPRD;

interacts with

 DDB1BIOGRID;

interacts with

 KPNA2MINT;

interacts with

 KPNA3HPRD;

interacts with

 KPNA5HPRD;

interacts with

 LYNHPRD;

interacts with

 MCM7MINT;

interacts with

 NUP50BIOGRID;

interacts with

 NUP50HPRD;

interacts with

 PPP1CAHPRD;

interacts with

 PPP1CBHPRD;

interacts with

 PPP1CCHPRD;

interacts with

 RNF123BIOGRID;

interacts with

 SKP2BIOGRID;

interacts with

 SKP2HPRD;

interacts with

 SPDYABIOGRID;

interacts with

 SPDYAHPRD;

interacts with

 SRCHPRD;

interacts with

 STMN1HPRD;

interacts with

 TRAF2BIOGRID;

interacts with

 TRAF2HPRD;

interacts with

 TRAF2MINT;

interacts with

 TRIM21BIOGRID;

interacts with

 TSC1BIOGRID;

interacts with

 TSC2BIOGRID;

interacts with

 TSC2HPRD;

interacts with

 UBAC1BIOGRID;

interacts with

 UBE2BBIOGRID;

interacts with

 UBE2D2BIOGRID;

interacts with

 UBE3ABIOGRID;

interacts with

 UCHL1BIOGRID;

interacts with

 UCHL1HPRD;

interacts with

 XPO1BIOGRID;

interacts with

 XPO1HPRD;

interacts with

 YES1HPRD;

interacts with

 YWHABHPRD;

interacts with

 YWHAEHPRD;

interacts with

 YWHAGHPRD;

interacts with

 YWHAHHPRD;

interacts with

 YWHAQBIOGRID;

interacts with

 YWHAQHPRD;

interacts with

 YWHAQMINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 BRCA1NCI_NATURE;

metabolic catalysis

 CTNNB1NCI_NATURE;

metabolic catalysis

 E2F1NCI_NATURE;

metabolic catalysis

 FOSNCI_NATURE;

metabolic catalysis

 FOXA1NCI_NATURE;

metabolic catalysis

 FOXO1NCI_NATURE;

metabolic catalysis

 FOXO3NCI_NATURE;

metabolic catalysis

 HES1NCI_NATURE;

metabolic catalysis

 IFNGNCI_NATURE;

metabolic catalysis

 IRF1NCI_NATURE;

metabolic catalysis

 JUNNCI_NATURE;

metabolic catalysis

 MAXNCI_NATURE;

metabolic catalysis

 MYCNCI_NATURE;

metabolic catalysis

 SIRT1NCI_NATURE;

metabolic catalysis

 TRIM28NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CDK2NCI_NATURE;

reacts with

 CDKN1BNCI_NATURE;

reacts with

 KPNA1NCI_NATURE;

reacts with

 RB1NCI_NATURE;

reacts with

 SKP2NCI_NATURE;

state change

 AKT1NCI_NATURE;

state change

 ITGAVNCI_NATURE;

state change

 ITGB3NCI_NATURE;

state change

 RHOANCI_NATURE;

state change

 VTNNCI_NATURE;

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