Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1326

Name

MAP3K8

Synonymous

AURA2|COT|EST|ESTF|MEKK8|TPL2|Tpl-2|c-COT;mitogen-activated protein kinase kinase kinase 8;MAP3K8;mitogen-activated protein kinase kinase kinase 8

Definition

Ewing sarcoma transformant|augmented in rheumatoid arthritis 2|cot (cancer Osaka thyroid) oncogene|proto-oncogene c-Cot|proto-oncogene serine/threoine protein kinase|tumor progression locus 2

Position

10p11.23

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AKT1NCI_NATURE;

in same component

 MAP3K14REACTOME;

in same component

 NFKB1REACTOME;

in same component

 PDPK1REACTOME;

in same component

 TNIP2REACTOME;

interacts with

 AKT1BIOGRID;

interacts with

 AKT1HPRD;

interacts with

 BMPR2HPRD;

interacts with

 CD40HPRD;

interacts with

 CHUKBIOGRID;

interacts with

 CHUKHPRD;

interacts with

 DDX3XHPRD;

interacts with

 GLG1HPRD;

interacts with

 GTF2IHPRD;

interacts with

 KSR2BIOGRID;

interacts with

 MAP2K1BIOGRID;

interacts with

 MAP2K4BIOGRID;

interacts with

 MAP2K4HPRD;

interacts with

 MAP3K14BIOGRID;

interacts with

 MAP3K14HPRD;

interacts with

 NFKB1BIOGRID;

interacts with

 NFKB1CELL_MAP;

interacts with

 NFKB1HPRD;

interacts with

 NFKB1MINT;

interacts with

 NFKB2BIOGRID;

interacts with

 NFKB2CELL_MAP;

interacts with

 NFKB2HPRD;

interacts with

 NFKB2MINT;

interacts with

 NFKBIAHPRD;

interacts with

 NFKBIBHPRD;

interacts with

 PAPOLAHPRD;

interacts with

 RELABIOGRID;

interacts with

 RELACELL_MAP;

interacts with

 RELAHPRD;

interacts with

 RELBHPRD;

interacts with

 RELBIOGRID;

interacts with

 RELCELL_MAP;

interacts with

 RELHPRD;

interacts with

 RELMINT;

interacts with

 RIPK1HPRD;

interacts with

 RPL6HPRD;

interacts with

 TNIP2BIOGRID;

interacts with

 TNIP2CELL_MAP;

interacts with

 TNIP2HPRD;

interacts with

 TNIP2MINT;

interacts with

 TRAF2BIOGRID;

interacts with

 TRAF2HPRD;

interacts with

 TRAF6HPRD;

Metabolic Interaction   [Top]

There is no record for MAP3K8

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AKT1NCI_NATURE;

reacts with

 MAP3K14REACTOME;

reacts with

 MAP3K8NCI_NATURE;

reacts with

 MAP3K8REACTOME;

reacts with

 NFKB1REACTOME;

reacts with

 PDPK1REACTOME;

reacts with

 TNIP2REACTOME;

state change

 MAP3K8REACTOME;

state change

 PDPK1REACTOME;

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