General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 1969 |
Name | EPHA2 |
Synonymous | ARCC2|CTPA|CTPP1|CTRCT6|ECK;EPH receptor A2;EPHA2;EPH receptor A2 |
Definition | ephrin type-A receptor 2|epithelial cell receptor protein tyrosine kinase|soluble EPHA2 variant 1|tyrosine-protein kinase receptor ECK |
Position | 1p36 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ACP1 | NCI_NATURE; |
in same component |
EFNA1 | NCI_NATURE; |
in same component |
GIT1 | NCI_NATURE; |
in same component |
NCK1 | NCI_NATURE; |
in same component |
PIK3CA | NCI_NATURE; |
in same component |
PIK3R1 | NCI_NATURE; |
in same component |
SRC | NCI_NATURE; |
in same component |
TIAM1 | NCI_NATURE; |
interacts with |
ACP1 | BIOGRID; |
interacts with |
Caskin1 | MINT; |
interacts with |
CBL | HPRD; |
interacts with |
CDH5 | HPRD; |
interacts with |
CLDN4 | HPRD; |
interacts with |
EFNA1 | HPRD; |
interacts with |
EFNA1 | MINT; |
interacts with |
EFNA2 | HPRD; |
interacts with |
EFNA3 | HPRD; |
interacts with |
EFNA4 | HPRD; |
interacts with |
EFNA5 | HPRD; |
interacts with |
EFNB1 | HPRD; |
interacts with |
EGFR | HPRD; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R2 | HPRD; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTK2 | INTACT; |
interacts with |
PTPN11 | BIOGRID; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN11 | INTACT; |
interacts with |
RASA1 | HPRD; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
SLA | BIOGRID; |
interacts with |
SLA | HPRD; |
interacts with |
TIAM1 | HPRD; |
interacts with |
TNFAIP1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ACP1 | NCI_NATURE; |
reacts with |
EFNA1 | NCI_NATURE; |
reacts with |
EPHA2 | NCI_NATURE; |
reacts with |
GIT1 | NCI_NATURE; |
reacts with |
NCK1 | NCI_NATURE; |
reacts with |
PIK3CA | NCI_NATURE; |
reacts with |
PIK3R1 | NCI_NATURE; |
reacts with |
SRC | NCI_NATURE; |
reacts with |
TIAM1 | NCI_NATURE; |
state change |
CDH1 | NCI_NATURE; |
state change |
CTNNA1 | NCI_NATURE; |
state change |
CTNNB1 | NCI_NATURE; |
state change |
CTNND1 | NCI_NATURE; |