Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1969

Name

EPHA2

Synonymous

ARCC2|CTPA|CTPP1|CTRCT6|ECK;EPH receptor A2;EPHA2;EPH receptor A2

Definition

ephrin type-A receptor 2|epithelial cell receptor protein tyrosine kinase|soluble EPHA2 variant 1|tyrosine-protein kinase receptor ECK

Position

1p36

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

EPHA2(h) --> Eck(h) (expression).
EPHA2(h) --> Eck(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

99N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
407N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
435N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
570Phosphoserine.Swiss-Prot 53.0
588Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
594Phosphotyrosine (by autocatalysis).Swiss-Prot 53.0
772Phosphotyrosine (by autocatalysis).Swiss-Prot 53.0
897Phosphoserine.Swiss-Prot 53.0
898Phosphothreonine.Swiss-Prot 53.0
901Phosphoserine.Swiss-Prot 53.0
921Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
930Phosphotyrosine.Swiss-Prot 53.0
772Phosphotyrosine15951569Phospho.ELM 6.0
930Phosphotyrosine15951569Phospho.ELM 6.0
921Phosphotyrosine15951569Phospho.ELM 6.0
588Phosphotyrosine15951569Phospho.ELM 6.0
594Phosphotyrosine15951569Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 16354651 - 16356651Agilent_014791

chr1

Promoter: 16354651 - 16356651GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 16354651 - 16356651GSE27584

chr1

Promoter: 16354651 - 16356651Agilent_014791_44K


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