| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2034 |
Name | EPAS1 |
Synonymous | ECYT4|HIF2A|HLF|MOP2|PASD2|bHLHe73;endothelial PAS domain protein 1;EPAS1;endothelial PAS domain protein 1 |
Definition | EPAS-1|HIF-1-alpha-like factor|HIF-1alpha-like factor|HIF-2-alpha|HIF2-alpha|PAS domain-containing protein 2|basic-helix-loop-helix-PAS protein MOP2|class E basic helix-loop-helix protein 73|endothelial PAS domain-containing protein 1|hypoxia-inducible fa |
Position | 2p21-p16 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
in same component |
ARNT | NCI_NATURE; |
in same component |
SIRT1 | NCI_NATURE; |
in same component |
TCEB1 | NCI_NATURE; |
in same component |
TCEB2 | NCI_NATURE; |
in same component |
VHL | NCI_NATURE; |
interacts with |
APC | BIOGRID; |
interacts with |
APC | INTACT; |
interacts with |
ARNT2 | BIOGRID; |
interacts with |
ARNT | BIOGRID; |
interacts with |
ARNTL2 | HPRD; |
interacts with |
ARNTL | BIOGRID; |
interacts with |
ARNTL | HPRD; |
interacts with |
EGLN1 | BIOGRID; |
interacts with |
EGLN1 | HPRD; |
interacts with |
EGLN2 | HPRD; |
interacts with |
EGLN3 | HPRD; |
interacts with |
EIF3E | HPRD; |
interacts with |
EP300 | HPRD; |
interacts with |
F12 | BIOGRID; |
interacts with |
MAX | BIOGRID; |
interacts with |
MAX | HPRD; |
interacts with |
MCM3 | BIOGRID; |
interacts with |
MCM7 | BIOGRID; |
interacts with |
MEF2C | BIOGRID; |
interacts with |
MEF2C | INTACT; |
interacts with |
PDK1 | MINT; |
interacts with |
PRKD1 | HPRD; |
interacts with |
PSMC3 | BIOGRID; |
interacts with |
Ruvbl1 | BIOGRID; |
interacts with |
SP1 | MINT; |
interacts with |
VHL | BIOGRID; |
interacts with |
VHL | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for EPAS1 | ||
Signaling Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
ARNT | NCI_NATURE; |
reacts with |
EPAS1 | NCI_NATURE; |
reacts with |
SIRT1 | NCI_NATURE; |
reacts with |
TCEB1 | NCI_NATURE; |
reacts with |
TCEB2 | NCI_NATURE; |
reacts with |
VHL | NCI_NATURE; |
state change |
APEX1 | NCI_NATURE; |
state change |
HIF1AN | NCI_NATURE; |