Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	3479
Name	IGF1
Synonymous	IGF-I\|IGF1A\|IGFI;insulin-like growth factor 1 (somatomedin C);IGF1;insulin-like growth factor 1 (somatomedin C)
Definition	IGF-IA\|IGF-IB\|MGF\|insulin-like growth factor I\|insulin-like growth factor IA\|insulin-like growth factor IB\|mechano growth factor\|somatomedin-C
Position	12q23.2
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	GRB10	NCI_NATURE;
in same component	IGF1R	IMID;
in same component	IGF1R	NCI_NATURE;
in same component	IRS1	NCI_NATURE;
in same component	NCK2	NCI_NATURE;
in same component	PTPN11	NCI_NATURE;
in same component	PTPN1	NCI_NATURE;
in same component	SHC1	NCI_NATURE;
in same component	SOS1	NCI_NATURE;
interacts with	IDE	BIOGRID;
interacts with	IGF1R	BIOGRID;
interacts with	IGFALS	BIOGRID;
interacts with	IGFBP2	BIOGRID;
interacts with	IGFBP3	BIOGRID;
interacts with	IGFBP4	BIOGRID;
interacts with	IGFBP5	BIOGRID;
interacts with	Igfbp5	MINT;
interacts with	IGFBP7	BIOGRID;
interacts with	IGSF1	BIOGRID;
interacts with	NOV	BIOGRID;
interacts with	TF	BIOGRID;

Metabolic Interaction [Top]
	There is no record for IGF1

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	GRB10	NCI_NATURE;
reacts with	IGF1	IMID;
reacts with	IGF1	NCI_NATURE;
reacts with	IGF1R	IMID;
reacts with	IGF1R	NCI_NATURE;
reacts with	IRS1	NCI_NATURE;
reacts with	NCK2	NCI_NATURE;
reacts with	PTPN11	NCI_NATURE;
reacts with	PTPN1	NCI_NATURE;
reacts with	SHC1	NCI_NATURE;
reacts with	SOS1	NCI_NATURE;
state change	CDH1	NCI_NATURE;
state change	CTNNA1	NCI_NATURE;
state change	CTNNB1	NCI_NATURE;
state change	CTNND1	NCI_NATURE;
state change	ESR1	NCI_NATURE;
state change	FN1	NCI_NATURE;
state change	ITGAV	NCI_NATURE;
state change	ITGB3	NCI_NATURE;
state change	PELP1	NCI_NATURE;
state change	SRC	NCI_NATURE;

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